Results 11 to 20 of about 18,861 (207)

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Consumption of low doses of fat prevents the postprandial rise in chylomicron particle concentration and remnant accumulation in healthy normolipidaemic males

Journal of Nutritional Science, 2012
Chylomicron particles are continually synthesised and secreted from the intestine even in the absence of ingested fat. It is possible that following consumption of low doses of fat the basal level of chylomicron secretion and subsequent metabolism are ...
Anthony P. James, John C. Mamo
doaj   +1 more source

Metabolism of chylomicrons by the isolated rat liver

Journal of Lipid Research, 1967
Isolated livers perfused with washed corn oil chylomicrons labeled in vivo with palmitic acid-1-14C removed a large proportion of the chylomicrons. Slices from these livers oxidized chylomicron fatty acid esters to both carbon dioxide and acetoacetate ...
Joseph A. Ontko, D.B. Zilversmit
doaj   +1 more source

Hepatic lipase treatment of chylomicron remnants increases exposure of apolipoprotein E.

Journal of Lipid Research, 1993
The consequences of hepatic lipase treatment of chylomicron remnants were studied. Rats were fed corn oil to induce production and secretion of chylomicrons and were then injected with polyclonal antiserum raised against hepatic lipase to specifically ...
DL Brasaemle, K Cornely-Moss, A Bensadoun   +2 more
doaj   +1 more source

N-3 fatty acids and chylomicron metabolism in the rat

Journal of Lipid Research, 1997
Dietary n-3 fatty acids (FAs) reduce postprandial triacylglycerol concentrations in humans by unknown mechanisms. Our goals were to reproduce this phenomenon in the rat, and then to determine the mechanism.
W S Harris, B E Hustvedt, E Hagen, M H Green, G Lu, C A Drevon   +5 more
doaj   +1 more source

Regulation of the hepatic removal of chylomicron remnants and beta-very low density lipoproteins in the rat.

Journal of Lipid Research, 1992
The contribution of the low density lipoprotein (LDL) receptor to the removal of chylomicron remnants was determined in vitro and in vivo by using interventions that up- or down-regulate the LDL receptor but not the LDL receptor-related protein (LRP). In
S Jäckle, F Rinninger, J Greeve, H Greten, E Windler   +4 more
doaj   +1 more source

Differences in the processing of chylomicron remnants and beta-VLDL by macrophages.

Journal of Lipid Research, 1990
To gain a detailed understanding of those factors that govern the processing of dietary-derived lipoprotein remnants by macrophages we examined the uptake and degradation of rat triacylglycerol-rich chylomicron remnants and rat cholesterol-rich beta-very
JL Ellsworth, LG Fong, FB Kraemer, AD Cooper   +3 more
doaj   +1 more source

Chylomicrons promote intestinal absorption of lipopolysaccharides

Journal of Lipid Research, 2009
Recent data suggest that dietary fat promotes intestinal absorption of lipopolysaccharides (LPS) from the gut microflora, which might contribute to various inflammatory disorders.
Sarbani Ghoshal, Jassir Witta, Jian Zhong, Willem de Villiers, Erik Eckhardt   +4 more
doaj   +1 more source

Transfer of human lymph chylomicron constituents to other lipoprotein density fractions during in vitro lipolysis

Journal of Lipid Research, 1982
To ascertain whether chylomicron constituents would be transferred to low density lipoprotein (LDL, d 1.019-1.063 g/ml) and high density lipoprotein (HDL, d 1.063-1.21 g/ml) density fractions during lipolysis in the absence of other lipoproteins, the in ...
E J Schaefer, M G Wetzel, G Bengtsson, R O Scow, H B Brewer, Jr, T Olivecrona   +5 more
doaj   +1 more source

Intestinal basolateral lipid substrate transport is linked to chylomicron secretion and is regulated by apoC-III

Journal of Lipid Research, 2019
Chylomicron metabolism is critical for determining plasma levels of triacylglycerols (TAGs) and cholesterol, both of which are risk factors for CVD.
Diana Li, Cayla N. Rodia, Zania K. Johnson, Minkyung Bae, Angelika Muter, Amy E. Heussinger, Nicholas Tambini, Austin M. Longo, Hongli Dong, Ji-Young Lee, Alison B. Kohan   +10 more
doaj   +1 more source