Results 21 to 30 of about 18,861 (207)

Dietary fat induced chylomicron-mediated LPS translocation in a bicameral Caco-2cell model

Lipids in Health and Disease, 2023
Background There is increasing evidence that dietary fat, especially saturated fat, promotes the translocation of lipopolysaccharide (LPS) via chylomicron production in the gut.
Monic M. M. Tomassen, Coen Govers, A. Paul Vos, Nicole J. W. de Wit   +3 more
doaj   +1 more source

New insights into the role of dietary triglyceride absorption in obesity and metabolic diseases

Frontiers in Pharmacology, 2023
The incidence of obesity and associated metabolic diseases is increasing globally, adversely affecting human health. Dietary fats, especially triglycerides, are an important source of energy for the body, and the intestine absorbs lipids through a series
Xiaojing Li, Qiaohong Liu, Yuqing Pan, Si Chen, Yu Zhao, Yiyang Hu, Yiyang Hu   +6 more
doaj   +1 more source

Low and high responders to pharmacological doses of β-carotene: proportion in the population, mechanisms involved and consequences on β-carotene metabolism

Journal of Lipid Research, 1998
The aim of this study was to assess the interindividual variability of chylomicron β-carotene response to a pharmacological load of β-carotene in the population, to identify the mechanisms responsible for this variability, and to evaluate its ...
Patrick Borel, Pascal Grolier, Nadia Mekki, Yves Boirie, Yvanne Rochette, Brigitte Le Roy, Marie C. Alexandre-Gouabau, Denis Lairon, Véronique Azais-Braesco   +8 more
doaj   +1 more source

The Biogenesis of Chylomicrons [PDF]

Annual Review of Physiology, 2010
The absorption of dietary fat is of increasing concern given the rise of obesity not only in the United States but throughout the developed world. This review explores what happens to dietary fat within the enterocyte. Absorbed fatty acids and monoacylglycerols are required to be bound to intracellular proteins and/or to be rapidly converted to ...
Charles M, Mansbach, Shadab A, Siddiqi
openaire   +3 more sources

Chylomicron catabolism differs between Hooded and albino laboratory rats.

Journal of Lipid Research, 1982
To extend previous reports that some aspects of lipid metabolism are different between Hooded and albino strains of laboratory rats, thoracic duct lymph chylomicrons were collected and their composition and metabolism were compared in this study ...
F Jeffery, T G Redgrave
doaj   +1 more source

Rapid initial removal of chylomicron remnants by the mouse liver does not require hepatically localized apolipoprotein E

Journal of Lipid Research, 2000
Apolipoprotein E (apoE) is a ligand for the low density lipoprotein receptor (LDLR) and the low density lipoprotein receptor-related protein (LRP). The aim of the present study was to clarify the role of hepatically localized apoE in the rapid initial ...
Kenneth C-W. Yu, Yuan Jiang, Wei Chen, Allen D. Cooper   +3 more
doaj   +1 more source

Apolipoprotein CIII predicts cardiovascular events in patients with coronary artery disease: a prospective observational study

Lipids in Health and Disease, 2020
Background Apolipoprotein CIII (apoCIII) is associated with triglyceride-rich lipoprotein metabolism and has emerged as independent marker for risk of cardiovascular disease.
Julius L. Katzmann, Christian M. Werner, Tatjana Stojakovic, Winfried März, Hubert Scharnagl, Ulrich Laufs   +5 more
doaj   +1 more source

Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma

Journal of Lipid Research, 1998
Triglyceride-rich lipoproteins (TRLs) that are modified during alimentary lipemia and their remnants are indicated to play an important role in the development of atherosclerosis.
Johan Björkegren, Fredrik Karpe, Ross W. Milne, Anders Hamsten   +3 more
doaj   +1 more source

Postprandial chylomicrons [PDF]

Journal of Lipid Research, 2004
We examined whether postprandial (PP) chylomicrons (CMs) can serve as vehicles for transporting cholesterol from endogenous cholesterol-rich lipoprotein (LDL+HDL) fractions and cell membranes to the liver via lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester transfer protein (CETP) activities.
Byung-Hong Chung, Ping Liang, Steve Doran, B. H. Simon Cho, Frank Franklin   +4 more
openaire   +2 more sources

Effects of cholesterol in chylomicron remnant models of lipid emulsions on apoE-mediated uptake and cytotoxicity of macrophages

Journal of Lipid Research, 2005
Chylomicron remnants have been suggested to be involved in the development of atherosclerosis. To investigate the mechanisms of chylomicron remnant-induced atherosclerosis, we prepared cholesterol (Chol)-containing emulsion particles as models for ...
Atsushi Sakurai, Shin-ya Morita, Kyoko Wakita, Yuko Deharu, Minoru Nakano, Tetsurou Handa   +5 more
doaj   +1 more source