Results 31 to 40 of about 26,516 (298)

ApoB48 as an Efficient Regulator of Intestinal Lipid Transport

Frontiers in Physiology, 2020
Fatty meals induce intestinal secretion of chylomicrons (CMs) containing apolipoprotein (Apo) B48. These CMs travel via the lymphatic system before entering the circulation.
Chunmin C. Lo, Karen T. Coschigano
doaj   +1 more source

Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36 [PDF]

, 2016
Cluster of differentiation 36 (CD36) variants influence fasting lipids and risk of metabolic syndrome, but their impact on postprandial lipids, an independent risk factor for cardiovascular disease, is unclear. We determined the effects of SNPs within a ~
Abumrad, Nada A, Allum, Fiona, Arnett, Donna K, Aslibekyan, Stella, Borecki, Ingrid B, Deloukas, Panos, Duan, Yanan, Grundberg, Elin, Hedman, Asa K, Hopkins, Paul N, Kraja, Aldi T, Love-Gregory, Latisha, McCarthy, Mark I, Ordovas, Jose M   +13 more
core   +2 more sources

Prandial Hypertriglyceridemia in Metabolic Syndrome Is Due to an Overproduction of Both Chylomicron and VLDL Triacylglycerol

Diabetes, 2013
The aim was to determine whether fed VLDL and chylomicron (CM) triacylglycerol (TAG) production rates are elevated in metabolic syndrome (MetS). Eight men with MetS (BMI 29.7 ± 1.1) and eight lean age-matched healthy men (BMI 23.1 ± 0.4) were studied ...
F. Shojaee-Moradie, Yuying Ma, Shao-ying Lou, R. Hovorka, A. Umpleby   +4 more
semanticscholar   +1 more source

Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice [PDF]

, 1994
To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice overexpressing apoE in the liver.
Gotoda T, Harada K, Kawamura M, Namba Y, Ohsuga J, Shimada M, Shimano H, Yamada N, Yamamoto K, Yazaki Y, 山田 信博   +10 more
core   +1 more source

Effect of alipogene tiparvovec (AAV1-LPL(S447X)) on postprandial chylomicron metabolism in lipoprotein lipase-deficient patients.

Journal of Clinical Endocrinology and Metabolism, 2012
BACKGROUND Lipoprotein lipase-deficient (LPLD) individuals display marked chylomicronemia and hypertriglyceridemia associated with increased pancreatitis risk. The aim of this study was to determine the effect of i.m.
A. Carpentier, F. Frisch, Sébastien M. Labbé, R. Gagnon, J. de Wal, S. Greentree, H. Petry, J. Twisk, D. Brisson, D. Gaudet   +9 more
semanticscholar   +1 more source

Relation of C-reactive protein to body fat distribution and features of the metabolic syndrome in Europeans and South Asians.

, 2001
OBJECTIVE: To investigate the association between circulating C-reactive protein (CRP) concentrations and indices of body fat distribution and the insulin resistance syndrome in South Asians and Europeans. DESIGN: : Cross-sectional study.
NG Forouhi, N Sattar, PM McKeigue, PM Ridker, PM Ridker, F Haverkate, W Koenig, MA Mendall, RP Tracy, JC Pickup, JS Yudkin, A Festa, PM McKeigue, PM McKeigue, PM McKeigue, JC Seidell, JR Patsch, J Highton, JP Després, AS Greenberg, T Chajek-Shaul, P Bjorntorp, P Ebeling, U Saxena   +23 more
core   +1 more source

Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents [PDF]

, 2017
peer-reviewedThe gut hormone glucagon-like peptide (GLP)-1 and its analogues represent a new generation of anti-diabetic drugs, which have also demonstrated propensity to modulate host lipid metabolism.
Cryan, John F., Dinan, Timothy G., Kent, Robert M., Mandal, Rupasri, Murphy, Kiera, O’Connor, Paula M., Patterson, Elaine, Peterson, Veronica L., Ross, R Paul, Ryan, Paul M, Seeley, Randy J., Stack, Helena, STANTON, CATHERINE, Wishart, David S.   +13 more
core   +4 more sources

Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying

Journal of Lipid Research, 2012
Acyl CoA:diacylglycerol acyltransferase (DGAT) 1 catalyzes the final step of triglyceride (TG) synthesis. We show that acute administration of a DGAT1 inhibitor (DGAT1i) by oral gavage or genetic deletion of intestinal Dgat1 (intestine-Dgat1−/−) markedly
G. Ables, K. Yang, S. Vogel, A. Hernandez-Ono, Shuiqing Yu, Jason J. Yuen, S. Birtles, L. Buckett, A. Turnbull, I. Goldberg, W. Blaner, Li-Shin Huang, H. Ginsberg   +12 more
semanticscholar   +1 more source

Triglyceride-rich lipoproteins prevent septic death in rats. [PDF]

, 1995
Triglyceride-rich lipoproteins bind and inactive bacterial endotoxin in vitro and prevent death when given before a lethal dose of endotoxin in animals.
Calhoun, MC, Feingold, KR, Grunfeld, C, Kane, JP, Kumwenda, ZL, Rapp, JH, Read, TE   +6 more
core  

Birth outcome in relation to licorice consumption during pregnancy.

, 2001
A role for glucocorticoids is suspected in the etiology of low birth weight. The authors tested whether maternal consumption of glycyrrhizin (an inhibitor of cortisol metabolism) in licorice affects birth weight in humans. A sample of 1,049 Finnish women
Järvenpää, AL, McKeigue, PM, Strandberg, TE, Vanhanen, H   +3 more
core   +1 more source