Results 31 to 40 of about 10,514 (223)
Defective lymphatic vasculature in obesity
Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley +1 more source
Hepatic lipase treatment of chylomicron remnants increases exposure of apolipoprotein E.
The consequences of hepatic lipase treatment of chylomicron remnants were studied. Rats were fed corn oil to induce production and secretion of chylomicrons and were then injected with polyclonal antiserum raised against hepatic lipase to specifically ...
DL Brasaemle+2 more
doaj
Causes and Consequences of Hypertriglyceridemia
Elevations in plasma triglyceride are the result of overproduction and impaired clearance of triglyceride-rich lipoproteins—very low-density lipoproteins (VLDL) and chylomicrons. Hypertriglyceridemia is characterized by an accumulation in the circulation
Chris J. Packard+2 more
doaj +1 more source
Abstract In health, the liver is a metabolically flexible organ that plays a key role in regulating systemic lipid and glucose concentrations. There is a constant flux of fatty acids (FAs) to the liver from multiple sources, including adipose tissue, dietary, endogenously synthesized from non‐lipid precursors, intrahepatic lipid droplets and recycling ...
Kieran Smith+2 more
wiley +1 more source
To ascertain whether chylomicron constituents would be transferred to low density lipoprotein (LDL, d 1.019-1.063 g/ml) and high density lipoprotein (HDL, d 1.063-1.21 g/ml) density fractions during lipolysis in the absence of other lipoproteins, the in ...
E J Schaefer+5 more
doaj
Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li+3 more
wiley +1 more source
Differences in the processing of chylomicron remnants and beta-VLDL by macrophages.
To gain a detailed understanding of those factors that govern the processing of dietary-derived lipoprotein remnants by macrophages we examined the uptake and degradation of rat triacylglycerol-rich chylomicron remnants and rat cholesterol-rich beta-very
JL Ellsworth+3 more
doaj
Mechanisms of chylomicron uptake into lacteals [PDF]
Right from birth, the lymphatics play a crucial role in dietary functions. A majority of the lipid absorbed from the newborn's lipid‐rich diet enters the blood circulation through the lymphatic system, which transports triglyceride‐loaded particles known as chylomicrons from the villi of the small intestine to the venous circulation near the heart.
openaire +2 more sources
Lipaemia retinalis: A question of chylomicrons? [PDF]
Lipaemia retinalis is a rarely described condition which occurs in certain types of both primary and secondary hyperlipidaemia. It presents with a striking fundal appearance. We report 7 cases of lipaemia retinalis and ocular manifestations in hyperlipidaemia which presented over a 12 year period to our hospitals.
G M Thompson+3 more
openaire +3 more sources
Safety, efficacy, and pharmacokinetics of oral testosterone undecanoate in males with hypogonadism
Abstract Background Testosterone deficiency results from insufficient testosterone production. Testosterone therapy may require dose titration to reach eugonadal serum testosterone concentrations. Objective The primary objective was the efficacy of oral testosterone undecanoate (TLANDO; Antares Pharma Inc.) in male patients with documented hypogonadism.
Martin Miner+8 more
wiley +1 more source