Results 51 to 60 of about 10,514 (223)

Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma

Journal of Lipid Research, 1998
Triglyceride-rich lipoproteins (TRLs) that are modified during alimentary lipemia and their remnants are indicated to play an important role in the development of atherosclerosis.
Johan Björkegren, Fredrik Karpe, Ross W. Milne, Anders Hamsten   +3 more
doaj  

Intraepineurial Fat Fraction: A Novel MR Neurography‐Based Biomarker in Transthyretin Amyloidosis Polyneuropathy

European Journal of Neurology, Volume 32, Issue 4, April 2025.
ABSTRACT Introduction Hereditary transthyretin amyloid polyneuropathy (ATTRv‐PN) is a rare and progressive neurodegenerative disorder characterized by axonal neuropathy and amyloid deposits. Early detection of disease onset and progression is crucial for timely therapeutic intervention.
Eva Sole Cruz, Etienne Fortanier, Constance P. Michel, Emilien Delmont, Annie Verschueren, Marc‐Adrien Hostin, David Bendahan, Shahram Attarian   +7 more
wiley   +1 more source

Chylomicron catabolism differs between Hooded and albino laboratory rats.

Journal of Lipid Research, 1982
To extend previous reports that some aspects of lipid metabolism are different between Hooded and albino strains of laboratory rats, thoracic duct lymph chylomicrons were collected and their composition and metabolism were compared in this study ...
F Jeffery, T G Redgrave
doaj  

Potential Causal Relationship Between Extensive Lipid Profiles and Various Hair Loss Diseases: Evidence From Univariable and Multivariable Mendelian Randomization Analyses

Journal of Cosmetic Dermatology, Volume 24, Issue 4, April 2025.
ABSTRACT Background Hair loss disorders, including non‐cicatricial forms such as alopecia areata (AA) and androgenetic alopecia (AGA), as well as cicatricial forms, represent significant dermatological concerns influenced by various factors, including lipid metabolism.
Yuhan Xie, Ruimin Bai, Landong Ren, Hengtong Fan, Huihui Tuo, Longmei Duan, Xiaolin Zhou, Chengyu Fang, Ziyan Li, Yan Zheng   +9 more
wiley   +1 more source

Sitosterolemia—An Underdiagnosed and Heterogeneous Lipid Disorder. A Case Series From a Tertiary Care Centre in Australia

Journal of Paediatrics and Child Health, Volume 61, Issue 4, Page 635-638, April 2025.
ABSTRACT Aims Sitosterolemia, is a disorder of increased plant sterol levels leading to a variable presentation and haematological manifestations. Although considered rare, the prevalence is likely underestimated due to the variable phenotype and challenges in diagnosis. The delayed diagnosis may lead to cardiovascular complications.
Dilhara Gamage, Kerryn Chisholm, Tatjana Kilo, Siew Ean Ooi, Shubha Srinivasan   +4 more
wiley   +1 more source

Multiple processes are involved in the uptake of chylomicron remnants by mouse peritoneal macrophages

Journal of Lipid Research, 1998
The processes responsible for the uptake of chylomicron remnants by macrophages were investigated using freshly isolated cells from low density lipoprotein (LDL) receptor, very low density lipoprotein (VLDL) receptor and apolipoprotein E knockout mice ...
Yoshio Fujioka, Allen D. Cooper, Loren G. Fong   +2 more
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Role of PNPLA3 in Hepatic Stellate Cells and Hepatic Cellular Crosstalk

Liver International, Volume 45, Issue 4, April 2025.
ABSTRACT Aims Since its discovery, the patatin‐like phospholipase domain containing 3 (PNPLA3) (rs738409 C>G p.I148M) variant has been studied extensively to unravel its molecular function. Although several studies proved a causal relationship between the PNPLA3 I148M variant and MASLD development and particularly fibrosis, the pathological mechanisms ...
Maria Castanho Martins, Emmanuel Dauda Dixon, Giulia Lupo, Thierry Claudel, Michael Trauner, Krista Rombouts   +5 more
wiley   +1 more source

Simultaneous measurements of chylomicron lipolysis and remnant removal using a doubly labeled artificial lipid emulsion: studies in normolipidemic and hyperlipidemic subjects.

Journal of Lipid Research, 1994
An artificial chylomicron-like lipid emulsion doubly labeled with tri[(N)3H]oleoylglycerol ([3H]TO) and cholesteryl [1-14C]oleate ([14C]CO) was infused intravenously into human subjects with the purpose of simultaneously measuring the plasma ...
E R Nakandakare, S A Lottenberg, H C Oliveira, M C Bertolami, K S Vasconcelos, G Sperotto, E C Quintão   +6 more
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Disentangling Organ‐Specific Roles of Farnesoid X Receptor in Bile Acid and Glucolipid Metabolism

Liver International, Volume 45, Issue 4, April 2025.
ABSTRACT Background and Aims The farnesoid X receptor (FXR) is an attractive pharmaceutical target for metabolic dysfunction‐associated steatotic liver disease (MASLD). However, its tissue‐specific roles in energy metabolism remain controversial, hindering the development of effective therapies. To address this, new approaches are required.
Tingting Li, Chenyang Fu, Zhongzheng Tang, Changkun Li, Duanyi Hua, Bei Liu, Zheying Tao, Jie Yang, Li Zhang, Tingting Cheng, Shujie Wang, Guang Ning, Yanyun Gu   +12 more
wiley   +1 more source

Effects of cholesterol in chylomicron remnant models of lipid emulsions on apoE-mediated uptake and cytotoxicity of macrophages

Journal of Lipid Research, 2005
Chylomicron remnants have been suggested to be involved in the development of atherosclerosis. To investigate the mechanisms of chylomicron remnant-induced atherosclerosis, we prepared cholesterol (Chol)-containing emulsion particles as models for ...
Atsushi Sakurai, Shin-ya Morita, Kyoko Wakita, Yuko Deharu, Minoru Nakano, Tetsurou Handa   +5 more
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