Results 61 to 70 of about 26,516 (298)
Metabolism of chylomicrons by the isolated rat liver
Isolated livers perfused with washed corn oil chylomicrons labeled in vivo with palmitic acid-1-14C removed a large proportion of the chylomicrons. Slices from these livers oxidized chylomicron fatty acid esters to both carbon dioxide and acetoacetate ...
Joseph A. Ontko, D.B. Zilversmit
doaj
Apolipoprotein A-IV regulates chylomicron metabolism-mechanism and function.
Dietary fat is an important mediator of atherosclerosis and obesity. Despite its importance in mediating metabolic disease, there is still much unknown about dietary fat absorption in the intestine and especially the detailed biological roles of ...
A. Kohan+7 more
semanticscholar +1 more source
ABSTRACT The primary features of the alpha‐gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with infusions of Cetuximab are specific for galactose alpha‐1,3‐galactose. (ii) In the USA, this IgE ab is induced by bites of the tick Amblyomma americanum. (iii) The anaphylactic reactions to food derived from non‐primate mammals
Thomas A. E. Platts‐Mills+3 more
wiley +1 more source
N-3 fatty acids and chylomicron metabolism in the rat
Dietary n-3 fatty acids (FAs) reduce postprandial triacylglycerol concentrations in humans by unknown mechanisms. Our goals were to reproduce this phenomenon in the rat, and then to determine the mechanism.
W S Harris+5 more
doaj
BackgroundAnderson's disease (AD) or chylomicron retention disease (CMRD) is a very rare hereditary lipid malabsorption syndrome. In order to discover novel mutations in the SAR1B gene and to evaluate the expression, as compared to healthy subjects, of ...
Amandine Georges+13 more
semanticscholar +1 more source
Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B. [PDF]
We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma cholesterol and triglyceride levels due to the disappearance of VLDL and LDL.
Gotoda Takanari+8 more
core +1 more source
Abstract In health, the liver is a metabolically flexible organ that plays a key role in regulating systemic lipid and glucose concentrations. There is a constant flux of fatty acids (FAs) to the liver from multiple sources, including adipose tissue, dietary, endogenously synthesized from non‐lipid precursors, intrahepatic lipid droplets and recycling ...
Kieran Smith+2 more
wiley +1 more source
The contribution of the low density lipoprotein (LDL) receptor to the removal of chylomicron remnants was determined in vitro and in vivo by using interventions that up- or down-regulate the LDL receptor but not the LDL receptor-related protein (LRP). In
S Jäckle+4 more
doaj
Role of the Gut in Diabetic Dyslipidemia
Type 2 diabetes (T2D) is associated with increased risk of cardiovascular disease (CVD). In insulin resistant states such as the metabolic syndrome, overproduction and impaired clearance of liver-derived very-low-density lipoproteins and gut-derived ...
Priska Stahel+3 more
doaj +1 more source
Omega‐3 fatty acids supplementation significantly reduced circulating levels of triglycerides (TG) (standardized mean difference [SMD] = −0.25, 95% confidence interval [CI] = −0.38 to −0.11) and total cholesterol (TC) (SMD = −0.12, 95% CI = −0.23 to −0.02), with no significant impact on the levels of high‐density lipoprotein cholesterol (HDL‐C), low ...
Chunyu Zhang+10 more
wiley +1 more source