Results 21 to 30 of about 87,578 (233)
Molecular determinants of pH regulation in the cardiac Na+-Ca2+ exchanger. [PDF]
, 2018 The cardiac Na+-Ca2+ exchanger (NCX) plays a critical role in the heart by extruding Ca2+ after each contraction and thus regulates cardiac contractility.
Goldhaber, Joshua I +4 more
core +1 more source
Frontiers in Chemistry, 2022 Enzyme function can be altered via modification of its amino acid residues, side chains and large-scale domain modifications. Herein, we have addressed the role of residue modification in catalytic activity and molecular recognition of an enzyme alpha ...
Pritam Biswas +13 more
doaj +1 more source
Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]
, 2000 The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard +3 more
core +1 more source
Enzymatic Pea Protein Hydrolysates Are Active Trypsin and Chymotrypsin Inhibitors
Foods, 2019 In this work, we report the potency of enzymatic hydrolysates of pea proteins against trypsin and chymotrypsin. Pea protein concentrate was digested with each of alcalase, chymotrypsin, pepsin, and trypsin, followed by membrane separation of the protein ...
Temitola Awosika, Rotimi E. Aluko
doaj +1 more source
Pharmaceutics, 2022 Till date, different types of conventional drugs have been used to fight tumors. However, they have significant flaws, including their usage being constrained because of their low bioavailability, poor supply, and serious side effects.
Amit Singh +3 more
doaj +1 more source
NMR solution structure of a chymotrypsin inhibitor from the Taiwan cobra Naja naja atra [PDF]
, 2013 The Taiwan cobra (Naja naja atra) chymotrypsin inhibitor (NACI) consists of 57 amino acids and is related to other Kunitz-type inhibitors such as bovine pancreatic trypsin inhibitor (BPTI) and Bungarus fasciatus fraction IX (BF9), another chymotrypsin ...
Chang, Long-Sen +3 more
core +2 more sources
Phylogenomic study of Burkholderia glathei-like organisms, proposal of 13 novel Burkholderia species and emended descriptions of Burkholderia sordidicola, Burkholderia zhejiangensis, and Burkholderia grimmiae [PDF]
, 2016 Partial gyrB gene sequence analysis of 17 isolates from human and environmental sources revealed 13 clusters of strains and identified them as Burkholderia glathei Glade (BGC) bacteria.
Cooper, Vaughn S +5 more
core +3 more sources
Angewandte Chemie, EarlyView.Structural water molecules in proteins are notoriously hard to detect in solution. Hyperpolarized water with UV radicals as polarizing agents provides the sensitivity and resolution to detect residue‐specific signatures of structural water with NMR spectroscopy.
Fabian Hecker +3 more
wiley +2 more sources
The regions of the sequence most exposed to the solvent within the amyloidogenic state of a protein initiate the aggregation process. [PDF]
, 2004 Formation of misfolded aggregates is an essential part of what proteins can do. The process of protein aggregation is central to many human diseases and any aggregating event needs to be prevented within a cell and in protein design.
AMORESANO, ANGELA +6 more
core +1 more source
Frontiers in Oncology, 2020 The Epithelial-Mesenchymal Transition (EMT) is an important concept in understanding the processes of oncogenesis, especially with respect to the relationship between cell proliferation and metastatic properties such as spontaneous cell motility ...
Trevor W. Stone
doaj +1 more source