Humán papillomavírus fertőzések = Human papillomavirus infections [PDF]
A survivin kifejeződése fontos lehet a méhnyakrák kialakulásában. A survivin és a HPV (human papillomavírus) közötti kapcsolatot vizsgálva megállapították, hogy a survivin promóter polimorfizmus nem jelent kockázati tényezőt a cervix carcinoma ...
Czeglédy, Judit +4 more
core
KSHV Targeted Therapy: An Update on Inhibitors of Viral Lytic Replication
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi’s sarcoma, primary effusion lymphoma and multicentric Castleman’s disease.
Natacha Coen +3 more
doaj +1 more source
Successful Treatment of Human Herpesvirus 6 Encephalomyelitis in Immunocompetent Patient
We report the case of human herpesvirus 6 (HHV-6) encephalomyelitis in an immunocompetent patient, which was confirmed by viral amplification from cerebrospinal fluid. Cidofovir was used followed by ganciclovir because of an adverse effect to probenecid.
Eric Denes +5 more
doaj +1 more source
Probable Donor-Derived Human Adenovirus Type 34 Infection in 2 Kidney Transplant Recipients From the Same Donor. [PDF]
Human adenovirus type 34 (HAdV-34) infection is a recognized cause of transplant-associated hemorrhagic cystitis and, in rare cases, tubulointerstitial nephritis.
Babu, Tara M. +9 more
core +1 more source
Symptomatic and asymptomatic viral recrudescence in solid-organ transplant recipients and its relationship with the antigen-specific CD8+ T-cell response [PDF]
Using ex vivo antigen-specific T-cell analysis, we found that symptomatic cytomegalovirus recrudescence in transplant recipients was coincident with reduced expression of gamma interferon (IFN-{gamma}) by virus-specific CD8+ T cells and an up-regulation ...
Crough, Tania +8 more
core +1 more source
Treating Adenovirus Infection in Transplant Populations: Therapeutic Options Beyond Cidofovir?
Adenovirus (AdV) infections can lead to significant morbidity and increased mortality in immunocompromised populations such as hematopoietic stem cell and solid organ transplant recipients. This review evaluates currently available and emerging therapies
Niyati Narsana, David Ha, Dora Y. Ho
doaj +1 more source
Primary treatment failure in acute retinal necrosis – A comprehensive review
Acute retinal necrosis (ARN) is a sight-threatening ophthalmic emergency that requires aggressive treatment to prevent irreversible vision loss. However, primary treatment failure (PTF), where the initial antiviral therapy is ineffective, is a common ...
Ankush Kawali +4 more
doaj +1 more source
BK Virus: Opportunity Makes a Pathogen [PDF]
More than 70% of the general population worldwide has serological evidence of exposure to Polyomavirus hominis type 1, better known as BK virus (BKV).
Hirsch, Hans H., Snydman, David R.
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Phosphonoamidate prodrugs of C5-substituted pyrimidine acyclic nucleosides for antiviral therapy [PDF]
Acyclic nucleoside phosphonates (ANPs) are nowadays one of the key drugs in the treatment of DNA virus and retrovirus infections. In this work, we report the synthesis and antiviral evaluation of phosphonoamidate and diamidates prodrugs of C5-pyrimidine ...
Albadry, Najmiyah +4 more
core +2 more sources
Development of CMX001 for the Treatment of Poxvirus Infections
CMX001 (phosphonic acid, [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]mono[3-(hexadecyloxy)propyl] ester) is a lipid conjugate of the acyclic nucleotide phosphonate, cidofovir (CDV).
George Painter +10 more
doaj +1 more source

