Tissue Distribution and Metabolization of Ciguatoxins in an Herbivorous Fish following Experimental Dietary Exposure to Gambierdiscus polynesiensis [PDF]
Marine Drugs, 2023 Ciguatoxins (CTXs), potent neurotoxins produced by dinoflagellates of the genera Gambierdiscus and Fukuyoa, accumulate in commonly consumed fish species, causing human ciguatera poisoning.
Rachel J. Clausing +8 more
doaj +2 more sources
Sensitive Detection of Ciguatoxins Using a Neuroblastoma Cell-Based Assay with Voltage-Gated Potassium Channel Inhibitors [PDF]
ToxinsCiguatoxins (CTXs) are neurotoxins responsible for ciguatera poisoning (CP), which affects more than 50,000 people worldwide annually. The development of analytical methods to prevent CP is a pressing global issue, and the N2a assay is one of the most ...
Toshiaki Yokozeki +4 more
doaj +2 more sources
Management of Ciguatoxin Risk in Eastern Australia [PDF]
Toxins, 2017 Between 2014 and 2016, five cases of ciguatera fish poisoning (CFP), involving twenty four individuals, were linked to Spanish Mackerel (Scomberomorus commerson) caught in the coastal waters of the state of New South Wales (NSW) on the east coast of ...
Hazel Farrell +3 more
doaj +3 more sources
Detection of Ciguatoxins and Tetrodotoxins in Seafood with Biosensors and Other Smart Bioanalytical Systems. [PDF]
Foods, 2023 Reverté J +3 more
europepmc +3 more sources
Synthesis of the A-F Fragment of the Pacific Ciguatoxin CTX3C by Iterative Ring-Closing Metathesis and Tsuji-Trost Allylation. [PDF]
Chemistry, 2023 The fully functionalized A−F ring system of the Pacific ciguatoxin CTX3C suitable for coupling to the I−M fragment of the natural product, has been synthesized from a simple glucal derivative. A six‐step sequence that features ring‐closing metathesis and stereoselective palladium‐mediated allylation has been deployed in an iterative manner to construct
Triantafyllakis M +4 more
europepmc +2 more sources
First Confirmed Occurrence of Ciguatera Poisoning in the UK from Imported Pinjalo Snapper (Pinjalo pinjalo) [PDF]
Marine DrugsThree people in England consumed fish steaks labeled as Red Snapper (Lutjanus bohar) originating from the Indian Ocean. Within 12 h, all three experienced sickness including nausea, vomiting, diarrhea, as well as myalgia and paresthesia.
Andrew D. Turner +4 more
doaj +2 more sources
Establishing a Receptor Binding Assay for Ciguatoxins: Challenges, Assay Performance and Application. [PDF]
Toxins (Basel)Díaz-Asencio L +4 more
europepmc +3 more sources
Liver Genomic Responses to Ciguatoxin: Evidence for Activation of Phase I and Phase II Detoxification Pathways following an Acute Hypothermic Response in Mice [PDF]
, 2008 Ciguatoxins (CTX) are polyether neurotoxins that target voltage-gated sodium channels and are responsible for ciguatera, the most common fish-borne food poisoning in humans. This study characterizes the global transcriptional response of mouse liver to a
Jeanine S. Morey +7 more
openalex +4 more sources
CiguaMOD I: A conceptual model of ciguatoxin loading in the Greater Caribbean Region. [PDF]
Harmful Algae, 2023 Parsons ML +6 more
europepmc +3 more sources
Chemical Research in Toxicology, 2021 Ciguatoxins (CTX) are potent marine neurotoxins, which can bioaccumulate in seafood, causing a severe and prevalent human illness known as ciguatera poisoning (CP). Despite the worldwide impact of ciguatera, effective disease management is hindered by a lack of knowledge regarding the movement and biotransformation of CTX congeners in marine food webs,
Jessica Kay Gwinn +5 more
openalex +4 more sources