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Advancing CIK cell immunotherapy: highlights from the second international conference on DC-CIK and CAR-CIK approaches [PDF]
Cancer Immunology, ImmunotherapyOn April 7, 2025, the 2nd International CIK Cell Conference was held in Monza, Italy, marking the establishment of the International Society for CIK Cells (ISCC).
Amit Sharma +11 more
doaj +3 more sources
Dendritic Cell-Cytokine-Induced Killer Cells Co-Loaded with WT1/MUC1/Poly(I:C) Enhance Antitumor Immune Responses In Vitro and In Vivo [PDF]
BiomoleculesDendritic cell-cytokine-induced killer (DC-CIK) therapy faces limitations due to antigenic heterogeneity and suboptimal immune activation. In this study, we developed a multi-antigen-loaded DC-CIK (Ag-DC-CIK) system that co-targets Wilms’ tumor 1 (WT1 ...
Huimin Liu +6 more
doaj +2 more sources
Inhibition of human gastric cancer growth by cytokine-induced killer cells plus chemotherapy with or without cadonilimab in a mouse xenograft tumor model [PDF]
Frontiers in ImmunologyBackgroundCytokine-induced killer (CIK) cell therapy has shown potent antitumor cytotoxicity. To date, no study has evaluated the efficacy and safety of combining CIK cell therapy with chemotherapy, with or without the immune checkpoint inhibitor (ICI ...
Wenwei Yang +4 more
doaj +2 more sources
PLoS ONE, 2023 Background Cytokine-induced killer (CIK) cells are heterogeneous lymphocytes from human peripheral blood mononucleated cells (PBMCs) co-cultured with several cytokines.
Chan-Keng Yang +6 more
doaj +2 more sources
Cytokine-induced killer cell treatment is superior to chemotherapy alone in esophageal cancer
Pathology and Oncology Research, 2023 Background: The therapeutic efficacy of cytokine-induced killer (CIK) cells versus dendritic cells (DC) co-cultured with CIK cells (DC-CIK) in treating esophageal cancer (EC) remains unclear due to the absence of a direct comparison of these two regimens.
Jiayang Sun +3 more
doaj +1 more source
Frontiers in Immunology, 2021 Cytokine-induced killer (CIK) cells are an ex vivo expanded heterogeneous cell population with an enriched NK-T phenotype (CD3+CD56+). Due to the convenient and relatively inexpensive expansion capability, together with low incidence of graft versus host
Xiaolong Wu +7 more
doaj +1 more source
BMC Immunology, 2023 Background Dendritic Cell Cytokine-induced killer cell (DC-CIK) coculture treatment in cancer immunotherapy has been shown to be effective. However, the cost of DC- CIK therapy is prohibitive for many patients, and the lack of standard manufacturing ...
Yi-Yen Lee +8 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2023 Background The number of clinical studies evaluating the benefit of cytokine-induced killer cell (CIK) therapy, an adoptive immunotherapy, for colorectal cancer (CRC) is increasing.
Jun Li +9 more
doaj +1 more source
Jurnal Akuakultur Indonesia, 2009 Domestication and genetic improvement of shrimp are required towards production of superior broodstock. BBPBAP Jepara had performed study on evaluation of genetic diversity of black tiger and white shrimp broodstock and their progenies produced in ...
Bambang Widyo Prastowo +2 more
doaj +1 more source
Frontiers in Immunology, 2022 Cytokine-induced killer cells (CIK) in combination with dendritic cells (DCs) have shown favorable outcomes in renal cell carcinoma (RCC), yet some patients exhibit recurrence or no response to this therapy.
Ying Zhang +7 more
doaj +1 more source