Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells
Adoptive cell therapy (ACT) using autologous cytokine-induced killer (CIK) cells is a promising treatment for metastatic carcinomas. In this study, we investigated the impact of RetroNectin on the proliferation, phenotype alternation, cytokine secretion,
Lu Han +3 more
doaj +1 more source
Background This study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).
Hansong Du, Jia Yang, Ying Zhang
doaj +1 more source
CIK Cell Therapy for Solid Tumor [PDF]
In recent years, the clinical trials on applying cytokine induced killer (CIK) cells to solid tumor therapy have been launched worldwide. CIK cells are a heterogeneous subset of ex-vivo expanded T lymphocytes, they present a mixed T-NK phenotype and are endowed with a MHC-unrestricted antitumor activity, which have showed great advantages in clinical ...
Jingjing Zhang, Yao Yang, Hualin Fu
openaire +2 more sources
Environmental Identification of Novel Enzymes for Polyurethane and Polyamide Degradation
Heteroatom‐containing plastics such as polyurethanes and nylons are produced at scale yet remain largely unrecycled. Biocatalysts offer a promising route to depolymerization under mild conditions. Here, we present a screening platform for the discovery of novel polyurethane‐ and nylon‐degrading enzymes from environmental samples and demonstrate ...
Malthe Kjær Bendtsen +17 more
wiley +2 more sources
Free Energies of Reaction for Aqueous Glycine Condensation Chemistry at Extreme Temperatures
This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Matthew Kroonblawd, Nir Goldman
wiley +1 more source
Phenotypic characterization and anticancer capacity of CD8+ cytokine-induced killer cells after antigen-induced expansion. [PDF]
Cytokine-induced killer cells (CIK) have been used in clinic for adoptive immunotherapy in a variety of malignant tumors and have improved the prognosis of cancer patients.
Jianhua Liu +4 more
doaj +1 more source
Background. PADI4 has extensive expression in many tumors. This study applied PADI4 as a tumor marker to stimulate DC- (dendritic cell-) CIK (cytokine-induced killer), an immunotherapy approach. Methods. A PADI4 expression plasmid was transfected into EC-
Chunyan Liu +6 more
doaj +1 more source
Development of the Collective Interaction Klystron (CIK) [PDF]
The CIK is a microwave source which relies on the negative mass instability for electron bunching, as opposed to the linear-drift ballistic bunching of conventional klystrons. A proof-of-principle (POP) CIK is being tested to verify the predictions of analyses, which indicate that the CIK is feasible in the 2-10-GHz region at megawatt to gigawatt power
J.A. Pasour, T.P. Hughes, K. Thomason
openaire +1 more source
CIK: A Path to GVL without GVHD? [PDF]
In allogeneic hematopoietic cell transplantation (HCT), the benefit of graft-versus-leukemia (GVL) effects often comes with the harm of graft-versushost disease (GVHD). In this issue of BBMT, Laport et al. [1] map a possible path toward GVL with a reduced risk of GVHD. GVL effects in humans were originally documented in observational studies by showing
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Cytokine-induced killer cell delivery enhances the antitumor activity of oncolytic reovirus. [PDF]
Oncolytic viruses (OV) have recently emerged as a promising therapeutic modality in cancer treatment. OV selectively infect and kill tumor cells, while sparing untransformed cells.
Xing Zhao +5 more
doaj +1 more source

