Results 31 to 40 of about 56,100 (193)

CIK: A Path to GVL without GVHD? [PDF]

open access: yesBiology of Blood and Marrow Transplantation, 2011
In allogeneic hematopoietic cell transplantation (HCT), the benefit of graft-versus-leukemia (GVL) effects often comes with the harm of graft-versushost disease (GVHD). In this issue of BBMT, Laport et al. [1] map a possible path toward GVL with a reduced risk of GVHD. GVL effects in humans were originally documented in observational studies by showing
openaire   +2 more sources

Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer

open access: yesJournal of Immunology Research, 2019
Background. PADI4 has extensive expression in many tumors. This study applied PADI4 as a tumor marker to stimulate DC- (dendritic cell-) CIK (cytokine-induced killer), an immunotherapy approach. Methods. A PADI4 expression plasmid was transfected into EC-
Chunyan Liu   +6 more
doaj   +1 more source

Cytokine-induced killer cell delivery enhances the antitumor activity of oncolytic reovirus. [PDF]

open access: yesPLoS ONE, 2017
Oncolytic viruses (OV) have recently emerged as a promising therapeutic modality in cancer treatment. OV selectively infect and kill tumor cells, while sparing untransformed cells.
Xing Zhao   +5 more
doaj   +1 more source

Classified Stable Matching

open access: yes, 2009
We introduce the {\sc classified stable matching} problem, a problem motivated by academic hiring. Suppose that a number of institutes are hiring faculty members from a pool of applicants.
Huang, Chien-Chung
core   +2 more sources

Role of the adaptor protein CIKS in the activation of the IKK complex [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2003
Nuclear factor kappaB (NF-kappaB) plays a pivotal role in numerous cellular processes, including stress response, inflammation, and protection from apoptosis. Therefore, the activity of NF-kappaB needs to be tightly regulated. We have previously identified a novel gene, named CIKS (connection to IkappaB-kinase and SAPK), able to bind the regulatory sub-
MAURO C   +6 more
openaire   +6 more sources

The Efficacy of CIK-Based Immunotherapies for Advanced Solid Tumors [PDF]

open access: yesTechnology in Cancer Research & Treatment, 2016
Objective: To investigate the efficacy of cytokine-induced killer cell-based immunotherapies in patients with advanced malignant solid tumors and the difference in clinical efficiency among 3 kinds of cytokine-induced killer cell-based immunotherapies. Methods: One hundred forty-six cases with advanced solid tumor, 230 cycles of cytokine-induced killer
Hongjin, Chu   +7 more
openaire   +2 more sources

A theorem on topologically massive gravity [PDF]

open access: yes, 1996
We show that for three dimensional space-times admitting a hypersurface orthogonal Killing vector field Deser, Jackiw and Templeton's vacuum field equations of topologically massive gravity allow only the trivial flat space-time solution.
A N Aliev   +9 more
core   +3 more sources

Growth of Human Colorectal Cancer SW1116 Cells Is Inhibited by Cytokine-Induced Killer Cells

open access: yesClinical and Developmental Immunology, 2011
Previous reports have suggested that treatment with cytokine-induced killer (CIK) cells may benefit patients with various types of tumor. The aim of this study was to evaluate the antitumor effects of CIK cells against the colorectal cancer line SW1116 ...
Yao Wang   +6 more
doaj   +1 more source

Cytokine-induced killer (CIK) cell therapy for patients with hepatocellular carcinoma: efficacy and safety

open access: yesExperimental Hematology & Oncology, 2012
Purpose To evaluate the efficacy of cytokine-induced killer (CIK) cell therapy in the treatment of hepatocellular carcinoma. Materials and methods Randomized phase II and III trials on CIK cell-based therapy were identified by electronic searches using a
Ma Yue   +5 more
doaj   +1 more source

Combining antiangiogenic therapy with adoptive cell immunotherapy exerts better antitumor effects in non-small cell lung cancer models. [PDF]

open access: yesPLoS ONE, 2013
INTRODUCTION: Cytokine-induced killer cells (CIK cells) are a heterogeneous subset of ex-vivo expanded T lymphocytes which are characterized with a MHC-unrestricted tumor-killing activity and a mixed T-NK phenotype.
Shujing Shi   +5 more
doaj   +1 more source

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