Results 21 to 30 of about 55,913 (181)

The possible molecular regulation mechanism of CIK cells inhibiting the proliferation of Human Lung Adenocarcinoma NCL-H157 Cells

open access: yesOpen Medicine, 2016
Cytokine-induced killer (CIK) cells were isolated and proliferation from human peripheral blood and cultured in appropriate growth medium. The biological characteristics of CIK cells were further determined by the characterization of surface markers by ...
Li Dengrui   +7 more
doaj   +1 more source

Adoptive immunotherapy of cytokine-induced killer cell therapy in the treatment of non-small cell lung cancer. [PDF]

open access: yesPLoS ONE, 2014
AIM:The aim of this study was to systemically evaluate the therapeutic efficacy of cytokine-induced killer (CIK) cells for the treatment of non-small cell lung cancer.
Min Wang   +10 more
doaj   +1 more source

Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells

open access: yesJournal of Immunology Research, 2016
Adoptive cell therapy (ACT) using autologous cytokine-induced killer (CIK) cells is a promising treatment for metastatic carcinomas. In this study, we investigated the impact of RetroNectin on the proliferation, phenotype alternation, cytokine secretion,
Lu Han   +3 more
doaj   +1 more source

Cytokine-induced killer cell/dendritic cell combined with cytokine-induced killer cell immunotherapy for treating advanced gastrointestinal cancer

open access: yesBMC Cancer, 2020
Background This study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).
Hansong Du, Jia Yang, Ying Zhang
doaj   +1 more source

Bayesian correlated clustering to integrate multiple datasets [PDF]

open access: yes, 2012
Motivation: The integration of multiple datasets remains a key challenge in systems biology and genomic medicine. Modern high-throughput technologies generate a broad array of different data types, providing distinct – but often complementary ...
Balasubramanian   +59 more
core   +2 more sources

CIK Cell Therapy for Solid Tumor [PDF]

open access: yesNano Biomedicine and Engineering, 2014
In recent years, the clinical trials on applying cytokine induced killer (CIK) cells to solid tumor therapy have been launched worldwide. CIK cells are a heterogeneous subset of ex-vivo expanded T lymphocytes, they present a mixed T-NK phenotype and are endowed with a MHC-unrestricted antitumor activity, which have showed great advantages in clinical ...
Jingjing Zhang, Yao Yang, Hualin Fu
openaire   +2 more sources

CIK Cells and HDAC Inhibitors in Multiple Myeloma [PDF]

open access: yesInternational Journal of Molecular Sciences, 2017
Multiple myeloma is the second most common hematological malignancy. Despite all the progress made in treating multiple myeloma, it still remains an incurable disease. Patients are left with a median survival of 4–5 years. The combined treatment of multiple myeloma with histone deacetylase inhibitors and cytokine-induced killer cells provides a ...
Stephan, David   +2 more
openaire   +3 more sources

An analytically solvable model of probabilistic network dynamics [PDF]

open access: yes, 2005
We present a simple model of network dynamics that can be solved analytically for uniform networks. We obtain the dynamics of response of the system to perturbations. The analytical solution is an excellent approximation for random networks. A comparison
Bar-Yam, Yaneer   +2 more
core   +2 more sources

Phenotypic characterization and anticancer capacity of CD8+ cytokine-induced killer cells after antigen-induced expansion. [PDF]

open access: yesPLoS ONE, 2017
Cytokine-induced killer cells (CIK) have been used in clinic for adoptive immunotherapy in a variety of malignant tumors and have improved the prognosis of cancer patients.
Jianhua Liu   +4 more
doaj   +1 more source

Primal-dual variable neighborhood search for the simple plant-location problem [PDF]

open access: yes, 2007
Copyright @ 2007 INFORMSThe variable neighborhood search metaheuristic is applied to the primal simple plant-location problem and to a reduced dual obtained by exploiting the complementary slackness conditions.
Brimberg, J   +3 more
core   +1 more source

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