Results 31 to 40 of about 55,913 (181)

Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer

open access: yesJournal of Immunology Research, 2019
Background. PADI4 has extensive expression in many tumors. This study applied PADI4 as a tumor marker to stimulate DC- (dendritic cell-) CIK (cytokine-induced killer), an immunotherapy approach. Methods. A PADI4 expression plasmid was transfected into EC-
Chunyan Liu   +6 more
doaj   +1 more source

Cytokine-induced killer cell delivery enhances the antitumor activity of oncolytic reovirus. [PDF]

open access: yesPLoS ONE, 2017
Oncolytic viruses (OV) have recently emerged as a promising therapeutic modality in cancer treatment. OV selectively infect and kill tumor cells, while sparing untransformed cells.
Xing Zhao   +5 more
doaj   +1 more source

Cytokine-induced killer (CIK) cell therapy for patients with hepatocellular carcinoma: efficacy and safety

open access: yesExperimental Hematology & Oncology, 2012
Purpose To evaluate the efficacy of cytokine-induced killer (CIK) cell therapy in the treatment of hepatocellular carcinoma. Materials and methods Randomized phase II and III trials on CIK cell-based therapy were identified by electronic searches using a
Ma Yue   +5 more
doaj   +1 more source

CIK: A Path to GVL without GVHD? [PDF]

open access: yesBiology of Blood and Marrow Transplantation, 2011
In allogeneic hematopoietic cell transplantation (HCT), the benefit of graft-versus-leukemia (GVL) effects often comes with the harm of graft-versushost disease (GVHD). In this issue of BBMT, Laport et al. [1] map a possible path toward GVL with a reduced risk of GVHD. GVL effects in humans were originally documented in observational studies by showing
openaire   +2 more sources

Development of the Collective Interaction Klystron (CIK) [PDF]

open access: yesProceedings of the 1989 IEEE Particle Accelerator Conference, . 'Accelerator Science and Technology, 2003
The CIK is a microwave source which relies on the negative mass instability for electron bunching, as opposed to the linear-drift ballistic bunching of conventional klystrons. A proof-of-principle (POP) CIK is being tested to verify the predictions of analyses, which indicate that the CIK is feasible in the 2-10-GHz region at megawatt to gigawatt power
J.A. Pasour, T.P. Hughes, K. Thomason
openaire   +1 more source

Combined therapy with cytokine-induced killer cells and oncolytic adenovirus expressing IL-12 induce enhanced antitumor activity in liver tumor model. [PDF]

open access: yesPLoS ONE, 2012
Both adoptive immunotherapy and gene therapy hold a great promise for treatment of malignancies. However, these strategies exhibit limited anti-tumor activity, when they are used alone.
Zhi Yang   +12 more
doaj   +1 more source

Innovative Clinical Perspectives for CIK Cells in Cancer Patients [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Cytokine-induced killer (CIK) cells are T lymphocytes that have acquired, in vitro, following extensive manipulation by Interferon gamma (IFN-γ), OKT3 and Interleukin 2 (IL-2) addition, the expression of several Natural Killer (NK) cell-surface markers.
Introna, Martino, Correnti, Fabio
openaire   +2 more sources

Non-minimal Einstein-Yang-Mills-Higgs theory: Associated, color and color-acoustic metrics for the Wu-Yang monopole model

open access: yes, 2007
We discuss a non-minimal Einstein-Yang-Mills-Higgs model with uniaxial anisotropy in the group space associated with the Higgs field. We apply this theory to the problem of propagation of color and color-acoustic waves in the gravitational background ...
A. B. Balakin   +13 more
core   +1 more source

Galerkin and Runge–Kutta methods: unified formulation, a posteriori error estimates and nodal superconvergence [PDF]

open access: yes, 2011
. We unify the formulation and analysis of Galerkin and Runge–Kutta methods for the time discretization of parabolic equations. This, together with the concept of reconstruction of the approximate solutions, allows us to establish a posteriori ...
A. Lozinski   +21 more
core   +5 more sources

Growth of Human Colorectal Cancer SW1116 Cells Is Inhibited by Cytokine-Induced Killer Cells

open access: yesClinical and Developmental Immunology, 2011
Previous reports have suggested that treatment with cytokine-induced killer (CIK) cells may benefit patients with various types of tumor. The aim of this study was to evaluate the antitumor effects of CIK cells against the colorectal cancer line SW1116 ...
Yao Wang   +6 more
doaj   +1 more source

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