Results 51 to 60 of about 55,801 (184)

Effect of dendritic cell-cytokine-induced killer cells in patients with advanced colorectal cancer combined with first-line treatment

World Journal of Surgical Oncology, 2017
Background Surgical resection combined with adjuvant chemotherapy is considered as the gold-standard treatment for advanced colorectal cancer patients. These patients have a poor 5-year survival rate of 5% or less.
Yunqing Xie, Lijie Huang, Luchuan Chen, Xiaowei Lin, Li Chen, Qiuhong Zheng   +5 more
doaj   +1 more source

Mechanism Design without Money via Stable Matching [PDF]

, 2011
Mechanism design without money has a rich history in social choice literature. Due to the strong impossibility theorem by Gibbard and Satterthwaite, exploring domains in which there exist dominant strategy mechanisms is one of the central questions in ...
Chen, Ning, Gravin, Nick, Lu, Pinyan
core  

Modeling Trophic Structure and Ecosystem Functioning of the Small Fish‐Dominated Largest Lake of Bangladesh

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Kaptai Lake is a developing ecosystem with a linear food web and thereby vulnerable to external influences. The apex predator, Catfish (TL‐3.364), occupied the top trophic niches, while the overabundant (B: 3.264 t/km2) Clupeid (TL‐2.56) dominated the lower trophic level in the food web. The higher values of ecotrophic efficiency for most of the groups
Debashis Kumar Mondal, Chengjie Yin, Kangshun Zhao, Muhammad Farooq, Md. Abdul Halim, Ruilong Wang, Jun Xu   +6 more
wiley   +1 more source

The role of photorespiration in abiotic stress conditions [PDF]

, 2019
Fotorespiracija je metabolički proces potaknut reakcijom oksigenacije enzima ribuloza-1,5- bisfosfat karboksilaze/oksigenaze. U toj se reakciji umjesto ugljikova dioksida, na ribulozu- 1,5-bisfosfat veže molekularni kisik.
Cik, Klara
core  

Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions

MedComm, Volume 7, Issue 3, March 2026.
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song, Yazhi Mo, Si Chen, Yuemei Chen, Chunying Zhang, Shanying Deng, Juan Liao, Yi He, Wei Wang, Weidong Zheng, Tingting Zeng   +10 more
wiley   +1 more source

Cytokine-induced killer (CIK) cells inhibit Plasmodium falciparum parasitemia through cytolytic effector activity in vitro

Immunobiology
Cytokine-induced killer (CIK) cells, with dual traits resembling natural killer (NK) and T cells, have shown a promising clinical efficacy against cancer in clinical application leading to licensing of CIK cells in many countries.
Rohulla Vaseq, Berthila Ferkamchwi, Hans Weiher, Veronika Lukacs-Kornek, Nahid Mahleqa, Marc P. Hübner, Amit Sharma, Ingo G.H. Schmidt-Wolf   +7 more
doaj   +1 more source

Dendritic cells decreased the concomitant expanded Tregs and Tregs related IL-35 in cytokine-induced killer cells and increased their cytotoxicity against leukemia cells.

PLoS ONE, 2014
Regulatory T cells (Tregs) are potent immunosuppressive cells and essential for inducing immune tolerance. Recent studies have reported that Tregs and Tregs related cytokines can inhibit the antitumor activity of cytokine-induced killer (CIK) cells, but ...
Ying Pan, Qianshan Tao, Huiping Wang, Shudao Xiong, Rui Zhang, Tianping Chen, Lili Tao, Zhimin Zhai   +7 more
doaj   +1 more source

Autologous Cytokine-Induced Killer Cell Immunotherapy Enhances Chemotherapy Efficacy against Multidrug-Resistant Tuberculosis

Journal of Immunology Research, 2022
Objective. Multidrug-resistant tuberculosis (MDR-TB) causes persistent infection and challenges tuberculosis control worldwide. T cell-mediated immunity plays a critical role in controlling Mycobacterium tuberculosis (Mtb) infection, and therefore ...
Peijun Tang, Xingnian Chen, Junchi Xu, Yunlong Hu, Zhijian Ye, Xiafang Wang, Yumei Xiao, Xinghua Shen, Jianping Zhang, Yanjun Feng, Cuilin Shi, Xin Yu, Lixian Yi, Xinchun Chen, Binfeng Lu, Ping Xu, Zhongwen Sun, Meiying Wu   +17 more
doaj   +1 more source

Efficacy of Cytokine-Induced Killer Cell Immunotherapy for Patients With Pathologically Pure Glioblastoma

Frontiers in Oncology, 2022
The most common malignant central nervous system tumor is glioblastoma multiforme (GBM). Cytokine-induced killer (CIK) cell therapy is a promising type of adoptive cell immunotherapy for various cancers.
Myung-Hoon Han, Jae Min Kim, Jin Hwan Cheong, Je Il Ryu, Yu Deok Won, Gun He Nam, Choong Hyun Kim   +6 more
doaj   +1 more source

CIKS/Act1-Mediated Signaling by IL-17 Cytokines in Context: Implications for How a CIKS Gene Variant May Predispose to Psoriasis [PDF]

The Journal of Immunology, 2012
Abstract Psoriasis is a relapsing skin disease characterized by abnormal keratinocyte proliferation and differentiation and by an influx of inflammatory immune cells. Recently, IL-17 cytokines have been strongly implicated as critical for the pathogenesis of this disease.
Søren Ulrik, Sønder, Andrea, Paun, Hye-Lin, Ha, Peter F, Johnson, Ulrich, Siebenlist   +4 more
openaire   +2 more sources