Results 51 to 60 of about 4,425,847 (185)

Combined therapy with cytokine-induced killer cells and oncolytic adenovirus expressing IL-12 induce enhanced antitumor activity in liver tumor model. [PDF]

PLoS ONE, 2012
Both adoptive immunotherapy and gene therapy hold a great promise for treatment of malignancies. However, these strategies exhibit limited anti-tumor activity, when they are used alone.
Zhi Yang, Qianzhen Zhang, Ke Xu, Juanjuan Shan, Junjie Shen, Limei Liu, Yanmin Xu, Feng Xia, Ping Bie, Xia Zhang, Youhong Cui, Xiu-Wu Bian, Cheng Qian   +12 more
doaj   +1 more source

Inhibition of human gastric cancer growth by cytokine-induced killer cells plus chemotherapy with or without cadonilimab in a mouse xenograft tumor model

Frontiers in Immunology
BackgroundCytokine-induced killer (CIK) cell therapy has shown potent antitumor cytotoxicity. To date, no study has evaluated the efficacy and safety of combining CIK cell therapy with chemotherapy, with or without the immune checkpoint inhibitor (ICI ...
Wenwei Yang, Jingwei Liu, Tiantian Hou, Xu Lu, Lin Yang   +4 more
doaj   +1 more source

Combinatorial approach with Cytokine-Induced Killer (CIK) cells and immunotools to fight HER2-positive breast cancer. Culture optimization of CIK cell expansion and function.

, 2023
reservedTargeting HER2 molecules for HER2+ breast cancer has become the standard care for both early and advanced-stage disease, on the other hand the treatment of metastatic HER+ tumors that develop resistance and lead to a disease progression, remained
NGO, TRONG HIEU
core  

Bocking assay of CIK cells by anti-DNAM-1 and anti-NKG2D.

, 2023
The blocking assay was performed to explore the potential mechanism for the cytolytic activity of CIK cells from HCC patients via a DNAM-1 and NKG2D-dependent manner (N = 2).
Ching-Hsun Hu (14328999), Jian-He Fang (636526), Chun-Yen Lin (298233), Chan-Keng Yang (9548675), Tse-Ching Chen (146382), Yung-Chang Lin (636527), Chien-Hao Huang (298239)   +6 more
core   +1 more source

Comparative Proteomic Analysis of Lysine Acetylation in Fish CIK Cells Infected with Aquareovirus. [PDF]

Int J Mol Sci, 2017
Grass carp (Ctenopharyngodon idellus) is an important worldwide commercial freshwater culture species. However, grass carp reovirus (GCRV) causes serious hemorrhagic disease in fingerlings and yearlings of fishes. To understand the molecular pathogenesis of host cells during GCRV infection, intensive proteomic quantification analysis of lysine ...
Guo H, Zhang J, Wang Y, Bu C, Zhou Y, Fang Q.   +5 more
europepmc   +4 more sources

Comparison of phenotype between CIK and DC-CIK cells on day28.

, 2014
Compared with CIK cells, NKT cells were significantly increased in DC-CIK cells. However, there was no significant difference in the expression of CD3+, CD4+, CD8+ T cells and NK cells between CIK cells and DC-CIK cells.
Huiping Wang (436545), Lili Tao (547628), Rui Zhang (13940), Tianping Chen (436546), Ying Pan (90050), Qianshan Tao (436548), Shudao Xiong (337784), Zhimin Zhai (436551)   +7 more
core   +1 more source

Environmental Identification of Novel Enzymes for Polyurethane and Polyamide Degradation

Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.
Heteroatom‐containing plastics such as polyurethanes and nylons are produced at scale yet remain largely unrecycled. Biocatalysts offer a promising route to depolymerization under mild conditions. Here, we present a screening platform for the discovery of novel polyurethane‐ and nylon‐degrading enzymes from environmental samples and demonstrate ...
Malthe Kjær Bendtsen, Andreas Møllebjerg, Samuel Peña‐Díaz, Rosie Graham, Nicolai Claus Petersen, Bjørk Nolsøe Isaksen, Mathias Carstensen, Martin B. Johansen, Andreas Sommerfeldt, Allan R. Petersen, Iddi Khamisi Chuma, Cecilie Ryberg, Thomas Rea Wittenborn, Virginia Gichuru, Huabing Wang, Carsten Scavenius, Alexander Sandahl, Daniel E. Otzen   +17 more
wiley   +2 more sources

Improved Activation toward Primary Colorectal Cancer Cells by Antigen-Specific Targeting Autologous Cytokine-Induced Killer Cells

Clinical and Developmental Immunology, 2012
Adoptive therapy of malignant diseases with cytokine-induced killer (CIK) cells showed promise in a number of trials; the activation of CIK cells from cancer patients towards their autologous cancer cells still needs to be improved.
Claudia Schlimper, Andreas A. Hombach, Hinrich Abken, Ingo G. H. Schmidt-Wolf   +3 more
doaj   +1 more source

The destiny of the resistance/susceptibility against GCRV is controlled by epigenetic mechanisms in CIK cells. [PDF]

Sci Rep, 2017
AbstractHemorrhagic disease caused by grass carp reovirus (GCRV) has severely threatened the grass carp (Ctenopharyngodon idella) cultivation industry. It is noteworthy that the resistance against GCRV infection was reported to be inheritable, and identified at both individual and cellular levels.
Shang X, Yang C, Wan Q, Rao Y, Su J, Su J.   +5 more
europepmc   +5 more sources

Combination therapy of irreversible electroporation and cytokine-induced killer cells for treating mice bearing panc02 pancreatic-cancer xenografts

Biochemistry and Biophysics Reports, 2023
The current study aimed to investigate the antitumor effects and potent mechanism of cytokine-induced killer (CIK) cells combined with irreversible electroporation (IRE) via Panc02 cell-bearing mouse model in vivo.
Baohua Wang, Huiyang Wang, Lan Yue, Qiang Chen, Junjie Dong, Tian'an Jiang   +5 more
doaj   +1 more source