Results 11 to 20 of about 164,456 (390)

Bioinspired magnetic cilia: from materials to applications

Microsystems & Nanoengineering, 2023
Microscale and nanoscale cilia are ubiquitous in natural systems where they serve diverse biological functions. Bioinspired artificial magnetic cilia have emerged as a highly promising technology with vast potential applications, ranging from soft ...
Seongjin Park, Geonjun Choi, Minsu Kang, W. Kim, Jangho Kim, Hoon Eui Jeong   +5 more
semanticscholar   +1 more source

Composition and function of the C1b/C1f region in the ciliary central apparatus

Scientific Reports, 2021
Motile cilia are ultrastructurally complex cell organelles with the ability to actively move. The highly conserved central apparatus of motile 9 × 2 + 2 cilia is composed of two microtubules and several large microtubule-bound projections, including the ...
Ewa Joachimiak, Anna Osinka, Hanan Farahat, Bianka Świderska, Ewa Sitkiewicz, Martyna Poprzeczko, Hanna Fabczak, Dorota Wloga   +7 more
doaj   +1 more source

Tau tubulin kinase 1 and 2 regulate ciliogenesis and human pluripotent stem cells–derived neural rosettes

Scientific Reports, 2023
Primary cilia are key regulators of embryo development and tissue homeostasis. However, their mechanisms and functions, particularly in the context of human cells, are still unclear.
Lucia Binó, Lukáš Čajánek
doaj   +1 more source

The LisH Domain-Containing N-Terminal Fragment is Important for the Localization, Dimerization, and Stability of Katnal2 in Tetrahymena

Cells, 2020
Katanin-like 2 protein (Katnal2) orthologs have a tripartite domain organization. Two highly conserved regions, an N-terminal LisH (Lis-homology) domain and a C-terminal AAA catalytic domain, are separated by a less conserved linker.
Ewa Joachimiak, Ewa Waclawek, Michal Niziolek, Anna Osinka, Hanna Fabczak, Jacek Gaertig, Dorota Wloga   +6 more
doaj   +1 more source

Quantifying cilia beat frequency using high‐speed video microscopy: Assessing frame rate requirements when imaging different ciliated tissues

Physiological Reports, 2022
Motile cilia are found in numerous locations throughout our body and play a critical role in various physiological processes. The most commonly used method to assess cilia motility is to quantify cilia beat frequency (CBF) via video microscopy.
Luke Scopulovic, Deanne Francis, Elvis Pandzic, Richard Francis   +3 more
doaj   +1 more source

Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance The oviduct is essential for female fertility due to its two main functions: transport and nourishment. While the nourishment role is mainly fulfilled by secretory cells, the relative contribution to the transport function by ciliated cells ...
Shuiqiao Yuan, Zhuqing Wang, Hongying Peng, S. Ward, G. Hennig, Huili Zheng, Wei Yan   +6 more
semanticscholar   +1 more source

Magnetic cilia carpets with programmable metachronal waves

Nature Communications, 2020
Metachronal waves commonly exist in natural cilia carpets. These emergent phenomena, which originate from phase differences between neighbouring self-beating cilia, are essential for biological transport processes including locomotion, liquid pumping ...
Hongri Gu, Q. Boehler, Haoyang Cui, E. Secchi, Giovanni Savorana, Carmela de Marco, S. Gervasoni, Quentin Peyron, Tian-Yun Huang, S. Pané, A. Hirt, D. Ahmed, B. Nelson   +12 more
semanticscholar   +1 more source

Cfap91-Dependent Stability of the RS2 and RS3 Base Proteins and Adjacent Inner Dynein Arms in Tetrahymena Cilia

Cells, 2022
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 + 2 ...
Marta Bicka, Ewa Joachimiak, Paulina Urbanska, Anna Osinka, Anna Konopka, Ewa Bulska, Dorota Wloga   +6 more
doaj   +1 more source

The regulatory roles of motile cilia in CSF circulation and hydrocephalus

Fluids and Barriers of the CNS, 2021
Background Cerebrospinal fluid (CSF) is an ultra-filtrated colorless brain fluid that circulates within brain spaces like the ventricular cavities, subarachnoid space, and the spine.
Vijay Kumar, Z. Umair, Shiv Kumar, Ravi Shankar Goutam, Soochul Park, Jaebong Kim   +5 more
semanticscholar   +1 more source

Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

bioRxiv, 2021
Previously, we showed that cholinergic interneurons of the dorsal striatum lose cilia in mice harboring the Parkinson’s disease associated, kinase activating, R1441C LRRK2 mutation (Dhekne et al., 2018).
Shahzad S Khan, Yuriko Sobu, H. S. Dhekne, F. Tonelli, Kerryn Berndsen, D. Alessi, S. Pfeffer   +6 more
semanticscholar   +1 more source