Changes in the cell shape and actin organization accompanying primary ciliogenesis in Xenopus epithelial cells [PDF]
Xenopus epithelial A6 cells produce primary cilia most readily when the confluent culture is serumdeprived, in contrast with various mammalian epithelial cells, which usually produce cilia in confluent cultures without serum starvation. Here, we observed
Riho Ishigami, Takako Kato-Minoura
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Cyclin-dependent kinase control of motile ciliogenesis
Cycling cells maintain centriole number at precisely two per cell in part by limiting their duplication to S phase under the control of the cell cycle machinery.
Eszter K Vladar+7 more
doaj +1 more source
Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. [PDF]
Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Agard, David A+3 more
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Signal transmission from the mechanical forces to the various intracellular activities is a fundamental process during tissue development. Despite their critical role, the mechanism of mechanical forces in the biological process is poorly understood.
Aya Miyazaki+12 more
semanticscholar +1 more source
Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome [PDF]
Defective primary ciliogenesis or cilium stability forms the basis of human ciliopathies, including Joubert syndrome (JS), with defective cerebellar vermis development.
Aza-Blac, P+44 more
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A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain [PDF]
Parkinson’s disease-associated LRRK2 kinase phosphorylates multiple Rab GTPases, including Rab8A and Rab10. We show here that LRRK2 kinase interferes with primary cilia formation in cultured cells, human LRRK2 G2019S iPS cells and in the cortex of LRRK2 ...
Alessi, Dario R.+8 more
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[Ciliogenesis in the mucous cells of the quail oviduct. II. Hormonal control] [PDF]
Daniel Sandoz+3 more
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ELECTRON MICROSCOPICAL OBSERVATIONS ON THE TRACHEAL EPITHELIUM OF THE ONE-HUMPED CAMEL (CAMELUS DROMEDARIUS) WITH SPECIAL REFERENCE TO CILIOGENESIS [PDF]
Yousria A. El-Rahman
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Use of ciliogenesis in the diagnosis of primary ciliary dyskinesia in a dog [PDF]
Cécile Clercx+7 more
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