Results 161 to 170 of about 21,394 (289)
Primary cilia and actin regulatory pathways in renal ciliopathies
Frontiers in NephrologyCiliopathies are a group of rare genetic disorders caused by defects to the structure or function of the primary cilium. They often affect multiple organs, leading to brain malformations, congenital heart defects, and anomalies of the retina or skeletal ...
Rita Kalot +6 more
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eLife, 2016 Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood.
Peter Walentek +5 more
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Exploring the role of fallopian ciliated cells in the pathogenesis of high-grade serous ovarian cancer [PDF]
, 2018 High-grade serous epithelial ovarian cancer (HGSOC) is the fifth leading cause of cancer death in women and the first among gynecological malignancies. Despite an initial response to standard chemotherapy, most HGSOC patients relapse.
Baldassarre G +9 more
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CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base [PDF]
, 2014 The transition zone (TZ) is a specialized compartment found at the base of cilia, adjacent to the centriole distal end, where axonemal microtubules (MTs) are heavily cross-linked to the surrounding membrane to form a barrier that gates the ciliary ...
Amack, Jeffrey D. +8 more
core +1 more source
Microvillar and ciliary defects in zebrafish lacking an actin-binding bioactive peptide amidating enzyme [PDF]
, 2018 © The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Scientific Reports 8 (2018): 4547, doi:10.1038/s41598-018-22732-9.The assembly of membranous ...
Eipper, Betty A. +6 more
core +2 more sources
Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis [PDF]
, 2019 Y. Yasuoka +3 more
openalex +1 more source
MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders [PDF]
, 2020 Angelisa Frasca +11 more
openalex +1 more source
Choanoflagellate Ciliogenesis Live Imaging v2
, 2023 This protocol removes the cilia/flagella from choanoflagellate cells and sets up the cells for live imaging of ciliogenesis. It has been developed for the species Salpingoeca rosetta, but may be portable into other choanoflagellate species. Cells begin to re-generate their cilia/flagella right after removal. The idea of using a cold shock with glycerol
openaire +1 more source
Frontiers in Cell and Developmental BiologyThe unicellular green alga, Chlamydomonas reinhardtii, has played a central role in discovering much of what is currently known about the composition, assembly, and function of cilia and flagella.
Wallace F. Marshall
doaj +1 more source
Nature Communications, 2018 Ciliogenesis is negatively regulated by the CP110-CEP97 complex, although the mechanism controlling mother centriole localization is poorly understood. Here, Huang et al.
Ning Huang +6 more
doaj +1 more source