Results 161 to 170 of about 36,064 (332)

Long‐Term Particulate Matter Exposure May Increase Risk of Chronic Rhinosinusitis WIth Nasal Polyposis: Results from an Exposure‐Matched Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Particulate matter ⩽2.5 µm in diameter (PM2.5) and its role in chronic rhinosinusitis (CRS) pathogenesis have gained heightened attention. We previously demonstrated that PM2.5 exposure may bias the nasal mucosa in CRS toward a Type 2 inflammatory pathway.
Rory J. Lubner, Mason Krysinski, Ping Li, Rakesh K. Chandra, Justin H. Turner, Naweed I. Chowdhury   +5 more
wiley   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Unexpected encounter with an intracameral cilium postcataract surgery

The Pan-American Journal of Ophthalmology
Background: Cataract surgery, a routine and highly successful ophthalmic intervention, is not immune to unexpected challenges. While complications are infrequent, their diverse nature necessitates a thorough understanding to ensure optimal patient ...
Anchal Tripathi, Atul Bhirud, Mohini Agrawal, Avinash Mishra, Biresh Raj   +4 more
doaj   +1 more source

Renal Cystic Disease: The Role of the Primary Cilium/Centrosome Complex in Pathogenesis [PDF]

, 2006
Brian J. Siroky, Lisa M. Guay‐Woodford
openalex   +1 more source

Diosgenin ameliorates silica‐induced tuberculosis in rats

Animal Models and Experimental Medicine, EarlyView.
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu, Selase Ativui, Michael Ofori, George Owusu, Cynthia Amaning Danquah, Paul Poku Sampene Ossei   +5 more
wiley   +1 more source

Cell-wide arrangement of Golgi/RE units depends on the microtubule organization

Cell Structure and Function
We have previously shown that Golgi stacks and recycling endosomes (REs) exist as Golgi/RE units in sea urchin embryos. In this study, we showed that Golgi/RE units were scattered throughout the cytoplasm at early developmental stages but gathered to ...
Tatsuya Tago, Syara Fujii, Shogo Sasaki, Maki Shirae-Kurabayashi, Naoaki Sakamoto, Takashi Yamamoto, Makoto Maeda, Tatsuya Ueki, Takunori Satoh, Akiko K. Satoh   +9 more
doaj   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

CFAP410 has a bimodular architecture with a conserved surface patch on its N-terminal leucine-rich repeat motif for binding interaction partners

Frontiers in Cell and Developmental Biology
Cilia and flagella associated protein 410 (CFAP410) is a protein localized at the basal body of cilia/flagella and plays essential roles in ciliogenesis. Multiple single amino acid mutations in CFAP410 have been identified in patients.
Alexander Stadler, Alexander Stadler, Heloisa B. Gabriel, Laryssa V. De Liz, Santiago Alonso-Gil, Santiago Alonso-Gil, Xuan Deng, Robbie Crickley, Katharina Korbula, Katharina Korbula, Barbora Mikolaskova, Barbora Mikolaskova, Sue Vaughan, Kaiyao Huang, Bojan Žagrović, Bojan Žagrović, Jack D. Sunter, Gang Dong, Gang Dong   +18 more
doaj   +1 more source

Polycystic kidney disease and the renal cilium (Review Article) [PDF]

, 2007
James A. Deane, Sharon D. Ricardo
openalex   +1 more source

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

Advanced NanoBiomed Research, EarlyView.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou, Jiuhong Yi, Yunlu Dai, Iek Man Lei   +3 more
wiley   +1 more source