Results 161 to 170 of about 40,574 (330)

Clinical and Molecular Genetic Characterization of Landau Kleffner Syndrome: An Observational Cohort and Experimental Study

open access: yesAnnals of Neurology, EarlyView.
Objective Landau–Kleffner syndrome (LKS), is a rare, poorly‐understood epileptic encephalopathy with spike–wave activation in sleep associated with mutations in GRIN2A, encoding the N‐Methyl‐D‐Aspartate receptor (NMDAR) GluN2A subunit. Physicians rely on empirical treatments, with scarce information on treatment efficacy and outcomes.
Adeline Ngoh   +15 more
wiley   +1 more source

The Meckel–Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation [PDF]

open access: bronze, 2006
Helen R. Dawe   +14 more
openalex   +1 more source

Perspective on Interdisciplinary Approaches on Chemotaxis

open access: yesAngewandte Chemie International Edition, EarlyView.
Chemotaxis is the movement of individual organisms towards or away from a chemical stimulus. This phenomenon is investigated in various disciplines, ranging from biology to physics and even engineering. This perspective aims to summarise recent developments in the field and encourage the unification of terminology to promote interdisciplinary knowledge
Juliane Simmchen   +18 more
wiley   +1 more source

Disparity of turbinal bones in placental mammals

open access: yesThe Anatomical Record, EarlyView.
Abstract Turbinals are key bony elements of the mammalian nasal cavity, involved in heat and moisture conservation as well as olfaction. While turbinals are well known in some groups, their diversity is poorly understood at the scale of placental mammals, which span 21 orders.
Quentin Martinez   +11 more
wiley   +1 more source

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

open access: yesThe Anatomical Record, EarlyView.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Deciphering vesicle-assisted transport mechanisms in cytoplasm to cilium trafficking

open access: yesFrontiers in Cellular Neuroscience
The cilium, a pivotal organelle crucial for cell signaling and proper cell function, relies on meticulous macromolecular transport from the cytoplasm for its formation and maintenance.
Mark Tingey   +3 more
doaj   +1 more source

The Kontsevich constants for the volume of the moduli of curves and topological recursion

open access: yes, 2010
We give an Eynard-Orantin type topological recursion formula for the canonical Euclidean volume of the combinatorial moduli space of pointed smooth algebraic curves. The recursion comes from the edge removal operation on the space of ribbon graphs. As an
Chapman, Kevin M.   +2 more
core  

Crossing the third‐level digital divide through digital literacy programs

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Digital literacy programs (DLPs) implemented by community‐anchored organizations have become a key focus toward achieving digital equity. However, there is a notable lack of quantitative empirical research that measures DLPs' effectiveness in supporting the achievement of tangible benefits of digital literacy (DL), beyond simply acquiring it ...
Yeweon Kim   +2 more
wiley   +1 more source

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