Results 171 to 180 of about 36,064 (332)
The mammalian Nek1 kinase is involved in primary cilium formation [PDF]
Ohad Shalom+3 more
openalex +1 more source
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo+2 more
wiley +1 more source
The primary cilium acts as a sensory organelle with diverse receptors and ion channels to detect extracellular cues and regulate cellular functions, including cell migration.
Mi Nam Lee+7 more
doaj
Disparity of turbinal bones in placental mammals
Abstract Turbinals are key bony elements of the mammalian nasal cavity, involved in heat and moisture conservation as well as olfaction. While turbinals are well known in some groups, their diversity is poorly understood at the scale of placental mammals, which span 21 orders.
Quentin Martinez+11 more
wiley +1 more source
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley +1 more source
Electron microscopic observation of the primary cilium in the pancreatic islets.
Masao Yamamoto, Katsuko Kataoka
openalex +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Localization of calcium-sensitive reversal mechanism in a cilium of paramecium.
Toshikazu Hamasaki, Yutaka Naitoh
openalex +2 more sources
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen+7 more
wiley +1 more source