The RFX-Type Transcription Factor DAF-19 Regulates Sensory Neuron Cilium Formation in C. elegans [PDF]
, 2000 Peter Swoboda +2 more
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Mechanosensation and the primary cilium
The FASEB Journal, 2008 The primary cilium has come under increased scrutiny as a site for mechano‐ and chemosensation by cells. We have undertaken a program of study using mouse renal cell lines from the cortical collecting duct and to quantify how mechanical forces arising from fluid shear transduce to a cellular response.
openaire +1 more source
TRiC Is a Structural Component of Mammalian Sperm Axonemes
Cytoskeleton, EarlyView.ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown +3 more
wiley +1 more source
The Primary Cilium of Connective Tissue Cells: Imaging by Multiphoton Microscopy [PDF]
, 2008 Eve Donnelly +2 more
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Differential Interleukin-10 and Gamma Interferon mRNA Expression in Lungs of Cilium-Associated Respiratory Bacillus-Infected Mice [PDF]
, 2001 Lon V. Kendall +4 more
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Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
Cytoskeleton, EarlyView.ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
Modelling the Fluid Mechanics of Cilia and Flagella in Reproduction and Development
, 2012 Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag anisotropy of
Blake, John R. +4 more
core +1 more source
Functional Genomics of the Cilium, a Sensory Organelle [PDF]
, 2005 Oliver E. Blacque +18 more
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Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Developmental Dynamics, EarlyView.Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin +8 more
wiley +1 more source
Stepless shape morphing polymer
SmartMat, Volume 4, Issue 1, February 2023., 2023 Reversible stepless discretionary morphing polymer is produced by simply training commercial ultrahigh molecular weight polyethylene (UHMWPE) via thermal treatment associated stretching. The key issue is that the crystals of UHMWPE memorize lots of temporary shapes as independent switching phases.
Lei Min +6 more
wiley +1 more source