Results 181 to 190 of about 41,549 (330)

Treatment of Coronary Perforation in a Bifurcation: Two‐Stent Strategies With Fenestrated Covered Stents

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Coronary perforations are a dreaded complication for any interventional cardiologist. The treatment of this complication is exceptionally difficult when it occurs in a coronary bifurcation. While a conservative approach or a balloon occlusion might be sufficient in some cases, additional treatment is sometimes necessary.
Jakob U. Lindner, Janine Pöss, Holger Thiele, Dmitry S. Sulimov   +3 more
wiley   +1 more source

Primary Cilium Disassembly in Mammalian Cells Occurs Predominantly by Whole-Cilium Shedding [PDF]

, 2018
Mary Mirvis, Kathleen A. Siemers, W. James Nelson, Tim Stearns   +3 more
openalex   +1 more source

LZTS2 Negatively Regulates Centrosomal CEP135 Levels and Microtubule Nucleation

Cytoskeleton, EarlyView.
ABSTRACT The microtubule cytoskeleton is a fundamental functional component of the cell. In vertebrate proliferating cells, centrosomes are the primary microtubule organizing center (MTOC), and their dysregulation has been linked to genomic instability and cancer.
Catarina Peneda, Joana N. Bugalhao, Marco Antonio Dias Louro, Andreia Henriques‐Soares, Monica Bettencourt‐Dias   +4 more
wiley   +1 more source

Cilium-by-cilium: unveiling hidden proteomic diversity and the molecular basis of ciliopathies. [PDF]

Signal Transduct Target Ther
Chiong M, Li H, Lavandero S.
europepmc   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Brain vascular stability relies on PAK2-cilia-PDGF-BB-HSPGs on basolateral side of endothelium. [PDF]

Life Sci Alliance
Prabhudesai S, Thirugnanam K, Song X, Yang H, Errede M, Girolamo F, Neumann T, Marzullo A, Bafti S, Vanderhoef K, Rarick KR, Spearman AD, Pan AY, Alvarez CA, Yang J, Zhang F, Dordick JS, Virgintino D, Wang L, Ramchandran R.   +19 more
europepmc   +1 more source

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

Cytoskeleton, EarlyView.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

The ciliopathy gene product Cep290 is required for primary cilium formation and microtubule network organization

, 2018
Elif Nur Firat‐Karalar
openalex   +1 more source

Bi-allelic Mutations in FAM149B1 Cause Abnormal Primary Cilium and a Range of Ciliopathy Phenotypes in Humans [PDF]

, 2019
Ranad Shaheen, Nan Jiang, Fatema Alzahrani, Nour Ewida, Tarfa Al‐Sheddi, Eman Alobeid, Damir Musaev, Valentina Stanley, Mais Hashem, Niema Ibrahim, Firdous Abdulwahab, Abduljabbar Alshenqiti, Fatma Müjgan Sönmez, Nadia Saqati, Hamad Alzaidan, Mohammad M. Al‐Qattan, Futwan Al‐Mohanna, Joseph G. Gleeson, Fowzan S. Alkuraya   +18 more
openalex   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source