Results 11 to 20 of about 25,606 (192)

Ameliorative effects of Brassica oleracea var. viridis ethanol extract and fractions on cimetidine-induced reproductive toxicity in male Wistar rats [PDF]

open access: yesFrontiers in Veterinary Science
BackgroundMale infertility is a global health issue, with pharmaceutical agents such as cimetidine contributing significantly to gonadotoxicity through antiandrogenic and oxidative mechanisms.
Emmanuel Orire Ikuomola   +5 more
doaj   +2 more sources

Evaluation of person-level heterogeneity of treatment effects in published multiperson N-of-1 studies: systematic review and reanalysis. [PDF]

open access: yes, 2018
OBJECTIVE:Individual patients with the same condition may respond differently to similar treatments. Our aim is to summarise the reporting of person-level heterogeneity of treatment effects (HTE) in multiperson N-of-1 studies and to examine the evidence ...
Balk, Ethan M   +8 more
core   +1 more source

Effects of temperature and wavelength choice on in-situ dissolution test of Cimetidine tablets

open access: yesJournal of Pharmaceutical Analysis, 2013
The effects of temperature and wavelength choice on in-situ dissolution test instrument of Cimetidine were studied. Absorbance (A)
Xin-Xia Li   +8 more
doaj   +1 more source

A DFT study of the chemical reactivity of cimetidine A, C and D in the gas, H2O, MeOH and EtOH solvents [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
% Fukui % DFT s KR nema In the present work, we have analyzed the chemical reactivity of cimetidine A, C and D in different solvents; through the evaluation of global and local DFT reactivity descriptors.
Mendoza Huizar Luis Humberto   +4 more
doaj   +1 more source

Formulation and Evaluation of Cimetidine as a Topical Preparation

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2007
Cimetidine is a H2 – receptor blocking drug, widely used for the treatment of stomach ulcer in addition to its immune response modifying activity. This study is carried out to formulate cimetidine in a stable topical preparation.The in vitro release of ...
Ali A Yas, Nidhal K. Marie
doaj   +1 more source

Cimetidine Does Not Inhibit 5-Aminolevulinic Acid Synthase or Heme Oxygenase Activity: Implications for Treatment of Acute Intermittent Porphyria and Erythropoietic Protoporphyria

open access: yesBiomolecules, 2023
Acute intermittent porphyria (AIP) is characterized by acute neurovisceral attacks that are precipitated by the induction of hepatic 5-aminolevulinic acid synthase 1 (ALAS1).
Makiko Yasuda   +5 more
doaj   +1 more source

Spinal cystic echinococcosis - a systematic analysis and review of the literature : part 2. treatment, follow-up and outcome [PDF]

open access: yes, 2013
Bone involvement in human cystic echinococcosis (CE) is rare, but affects the spine in approximately 50% of cases. Despite significant advances in diagnostic imaging techniques, surgical treatment and introduction of pharmacological therapy, spinal ...
Blum, Johannes   +4 more
core   +3 more sources

Cimetidine Pharmacodynamics and Pharmacokinetics in Healthy Subjects: A Comparison of Tablets and Suspension

open access: yesCanadian Journal of Gastroenterology, 1994
The objective of this study was to compare the effect of cimetidine 200 mg tablet with that of cimetidine suspension (200 mg/10 mL), a 20 mL suspension of 800 mg magnesium hydroxide and 912 mg aluminum hydroxide, and matching placebo on intragastric pH ...
ABR Thomson   +4 more
doaj   +1 more source

Pharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine

open access: yesPharmaceutics, 2018
A sensitive and simple chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to evaluate memantine in rat plasma. Memantine and propranolol (internal standard) in rat plasma was extracted using a methanol precipitation method.
Young A. Choi   +2 more
doaj   +1 more source

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats

open access: yesPharmaceutics, 2019
Previous observations demonstrated that cimetidine decreased the clearance of procainamide (PA) and/or N-acetylprocainamide (NAPA; the primary metabolite of PA) resulting in the increased systemic exposure and the decrease of urinary excretion.
Yoo-Seong Jeong   +4 more
doaj   +1 more source

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