Results 41 to 50 of about 34,140 (239)
Chronic calcific periarthritis of the elbow treated by cimetidine administration: Five cases
Journal of Orthopaedic Surgery, 2017 Calcific periarthritis or calcific tendinitis occurs most frequently in the shoulder and rarely in the elbow. Cimetidine was previously reported to be effective for chronic calcific periarthritis of the shoulder.
Hiroo Kimura +6 more
doaj +1 more source
BMC Cancer, 2008 Background Cimetidine, a histamine type-2 receptor antagonist, has been reported to inhibit the growth of glandular tumors such as colorectal cancer, however the mechanism of action underlying this effect is unknown.
Sakashita Hideaki +2 more
doaj +1 more source
Cells, 2022 Despite potent anticancer activity, the clinical utilization of cisplatin is limited due to nephrotoxicity. As Organic Cation Transporter 2 (OCT2) has been shown to be one of the key transporters involved in the uptake of cisplatin into renal proximal ...
Hardik Mody +3 more
doaj +1 more source
Transport of six tyrosine kinase inhibitors: active or passive ? [PDF]
, 1995 Transport of erlotinib, gefitinib, sorafenib, sunitinib, dasatinib and crizotinib can be active or passive, which was studied by measuring uptake at low (4 °C; passive) and normal temperature (37 °C; active and passive) and by the use of specific organic
J. Honeywell, Richard +3 more
core +6 more sources
Animal Models and Experimental Medicine, 2019 Background The increasing incidence of chemically induced infertility is both a social threat and a threat to the continuation of life itself. Treatment or management therapy is often expensive. This study investigated the effects of acetone extract of a
Ngozi Joy Onwuemene +2 more
doaj +1 more source
Impacts of compound properties and sediment characteristics on the sorption behaviour of pharmaceuticals in aquatic systems [PDF]
, 2016 Sorption is a key factor in determining the persistence, attenuation and bioavailability of sediment-associated contaminants. However, our understanding of the sorption behaviour of pharmaceuticals in sediments is poor. In this study, we investigated the
Al-Khazrajy, Omar S A +1 more
core +1 more source
Interactions of Human- and Rat-Organic Anion Transporters With Pravastatin and Cimetidine
Journal of Pharmacological Sciences, 2004 We have elucidated the interactions of human and rat organic anion transporters (hOATs and rOATs) with pravastatin and cimetidine. Pravastatin inhibited hOAT1/rOAT1, hOAT2/rOAT2, hOAT3/rOAT3, and hOAT4. The mode of inhibition was noncompetitive for hOAT1
Suparat Khamdang +8 more
doaj +1 more source
Tubular secretion of creatinine and kidney function: an observational study. [PDF]
, 2020 BackgroundPrior papers have been inconsistent regarding how much creatinine clearance (CrCl) overestimates glomerular filtration rate (GFR). A recent cross-sectional study suggested that measurement error alone could entirely account for the longstanding
Hsu, Chi-Yuan +5 more
core
Cyclosporin a hepatotoxicity in 66 renal allograft recipients [PDF]
, 1981 Liver functional abnormalities were seen in 13 (19.7%) of 66 recipients of cadaveric renal homografts treated with cyclosporin A and prednisone. However, such presumed hepatotoxicity was a minor problem in the use of cyclosporin A.
Iwatsuki, S, Klintmalm, GBG, Starzl, TE
core +1 more source
Journal of Pharmacological Sciences, 2003 The effects of cimetidine on rat adjuvant arthritis (AA) and rat osteoclast differentiation were studied. For the in vivo experiments, AA was induced by injections of Mycobacterium tuberculosis H37RA either subcutaneously into the base of the tail or ...
Katsunori Yamaura +4 more
doaj +1 more source