Dimeric Cinchona alkaloids. [PDF]
Mol Divers, 2015 Nature is full of dimeric alkaloids of various types from many plant families, some of them with interesting biological properties. However, dimeric Cinchona alkaloids were not isolated from any species but were products of designed partial chemical synthesis.
Boratyński PJ.
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Electrochemical Behavior of Some Cinchona Alkaloids Using Screen-Printed Electrodes [PDF]
SensorsAn effective deposition of a cinchonine layer on a platinum metal surface can be easily achieved through the cathodic reduction of a cinchonine hydrochloride methanolic solution at a controlled potential of −220 mV vs. the silver standard electrode (SSE).
Tonino Caruso, Laura Palombi
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Stereoselective α-Chlorination of β-Keto Esters in the Presence of Hybrid Amide-Based Cinchona Alkaloids as Catalysts. [PDF]
J Org Chem, 2021 We report an enantioselective phase transfer α-chlorination of β-keto esters catalyzed by hybrid amide-based Cinchona derivatives. The chlorination process proceeds with proper quantitative yields (up to
Majdecki M, Grodek P, Jurczak J.
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One-Pot Synthesis of Novel Chiral β-Amino Acid Derivatives by Enantioselective Mannich Reactions Catalyzed by Squaramide Cinchona Alkaloids [PDF]
Molecules, 2013 An efficient one-pot synthesis of novel β-amino acid derivatives containing a thiadiazole moiety was developed using a chiral squaramide cinchona alkaloid as organocatalyst.
Kankan Zhang +8 more
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Highly Enantioselective Epoxidation of α,β-Unsaturated Ketones Using Amide-Based Cinchona Alkaloids as Hybrid Phase-Transfer Catalysts. [PDF]
Org Lett, 2020 A series of 20 one chiral epoxides were obtained with excellent yields (up to 99%) and enantioselectivities (up to >99% ee) using hybrid amide-based Cinchona alkaloids.
Majdecki M +2 more
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New Members of the Cinchona Alkaloids Family: Assembly of the Triazole Heterocycle at the 6′ Position [PDF]
Molecules, 2021 The substance class of the well-known Cinchona alkaloids is widened by 6′-Amino-cinchonine and 6′-Amino-cinchonidine, novel compounds which incorporate a primary amino function in the quinolinic ring system.
Catalin Vasile Maftei +3 more
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Cinchona alkaloids as natural fetal hemoglobin inducing agents in human erythroleukemia cells. [PDF]
RSC Adv, 2019 Pharmacologically mediated reactivation of γ-globin gene with an increase in fetal hemoglobin production, is a cost effective experimental therapeutic intervention for the management of β-hemoglobinopathies. Investigation of new pharmacological agents as
Iftikhar F, Ali H, Musharraf SG.
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New α- and β-cyclodextrin derivatives with cinchona alkaloids used in asymmetric organocatalytic reactions [PDF]
Beilstein Journal of Organic Chemistry, 2019 The preparation of new organocatalysts for asymmetric syntheses has become a key stage of enantioselective catalysis. In particular, the development of new cyclodextrin (CD)-based organocatalysts allowed to perform enantioselective reactions in water and
Iveta Chena Tichá +2 more
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In Silico Screening and Designing Synthesis of Cinchona Alkaloids Derivatives as Potential Anticancer [PDF]
Journal of Tropical Life Science, 2017 P-glycoprotein (P-gp) resistance in cancer cells decreases intracellular accumulation of various anticancer drugs. This multidrug resistance (MDR) protein can be modulated by a number of non-cytotoxic drugs.
Muhammad Hanafi +4 more
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Cinchona alkaloids - acid, anion-driven fluorescent INHIBIT logic gates with a receptor1-fluorophore-spacer-receptor2 format and PET and ICT mechanisms. [PDF]
RSC Adv, 2023 Agius N, Magri DC.
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