Results 91 to 100 of about 187,468 (290)

Diastereodivergent and Enantioselective [4+2] Annulations of γ-Butenolides with Cyclic 1-Azadienes

open access: yesMolecules, 2015
An asymmetric annulation reaction of γ-butenolides and cyclic 1-azadienes containing a 1,2-benzoisothiazole-1,1-dioxide motif has been studied, proceeding in a tandem Michael addition-aza-Michael addition sequence.
Chao Li, Kun Jiang, Ying-Chun Chen
doaj   +1 more source

Anion-π catalysis: Bicyclic products with four contiguous stereogenic centers from otherwise elusive diastereospecific domino reactions on π-acidic surfaces [PDF]

open access: yes, 2017
Anion–π interactions have been introduced recently to catalysis. The idea of stabilizing anionic intermediates and transition states on π-acidic surfaces is a new fundamental concept.
Cotelle, Yoann   +5 more
core   +4 more sources

Alkaloids unveiled: A comprehensive analysis of novel therapeutic properties, mechanisms, and plant-based innovations

open access: yesIntelligent Pharmacy
Alkaloids, naturally occurring compounds in a diverse range of plant species (Coffea spp., Erythroxylum coca, Cinchona spp. etc.), hold vast potential for biological, medicinal, and pharmacological applications. As the global focus shifts towards natural
Sarvananda Letchuman   +4 more
doaj   +1 more source

Towards an Asymmetric Organocatalytic α-Azidation of β-Ketoesters

open access: yesMolecules, 2018
Detailed investigations concerning the organocatalytic (asymmetric) α-azidation of prochiral β-ketoesters were carried out. It was shown that the racemic version of such a reaction can either be carried out under oxidative conditions using ...
Maximilian Tiffner   +4 more
doaj   +1 more source

Coadsorption of Cinchona Alkaloids on Supported Palladium: Nonlinear Effects in Asymmetric Hydrogenation and Resistance of Alkaloids Against Hydrogenation [PDF]

open access: yes, 2018
The transient behavior of the adsorption of cinchona alkaloid modifiers on Pd/TiO2 has been investigated in situ during the enantioselective hydrogenation of 4-methoxy-6-methyl-2-pyrone (1).
Baiker, A., Huck, W.-R, Mallat, T.
core  

Exploring Nanotechnologies for the Effective Therapy of Malaria using Plant-Based Medicines [PDF]

open access: yes, 2016
Malaria is a potentially lethal disease caused by species of the plasmodium parasite. Despite the advances in the interventions for its control and approaches to manage fatality, morbidity and mortality rates associated with malaria are still high.
Oga, Enoche Florence, Singh, Kamalinder
core   +1 more source

Optimizing ex vitro Acclimatization of Cinchona spp.: Towards the establishment of an industrial crop in Colombia

open access: yesRevista Colombiana de Biotecnología
Efforts to optimize ex vitro transfer techniques of un-rooted in vitro shoots of Cinchona spp. (Rubiaceae) a native tree of the andean forests, are crucial for promoting sustainable cultivation practices of this medicinal plant.
Juan David Saavedra Correa   +2 more
doaj   +1 more source

Catalytic and Photoluminescence Properties of the First‐ and Second‐Sphere Coordination of Lanthanide Complexes

open access: yesChemistry – A European Journal, Volume 31, Issue 61, November 3, 2025.
The Michael donor and the Michael acceptor are activated via hydrogen bonding interactions within the second‐sphere coordination of europium complexes. Abstract The efficient binding of receptors Lk (Lk = L5‐L8) to [Eu(hfac)3] (H‐hfac = 1,1,1,5,5,5‐hexafluoropentane‐2,4‐dione) allows (i) to gather the basic unit‐containing tridentate ligands Lk and the
Giau Le‐Hoang   +4 more
wiley   +1 more source

Controlling the stereochemistry in 2-oxo-aldehyde-derived Ugi adducts through the cinchona alkaloid-promoted electrophilic fluorination

open access: yesBeilstein Journal of Organic Chemistry, 2020
In this report, we introduce a new strategy for controlling the stereochemistry in Ugi adducts. Instead of controlling stereochemistry directly during the Ugi reaction we have attempted to stereodefine the chiral center at the peptidyl position through ...
Yuqing Wang   +9 more
doaj   +1 more source

Effect of Crocus sativus Stigma (saffron) alone or in combination with chloroquine on chloroquine sensitive strain of Plasmodium berghei in mice [PDF]

open access: yes, 2015
Introduction: In malaria treatment protocols, treatment failure or drug resistance of synthesized drugs like alkaloids related to quinine, and aminoquinolines are the main problems now.
Abedi-Madiseh, Somayeh.   +3 more
core   +1 more source

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