Results 31 to 40 of about 187,468 (290)

The Activity of NADP(H) Oxidoreductase of Elicitated Cell Culture of Cinchona ledgeriana Moens

Jurnal Ilmu Pertanian Indonesia, 2020
Cinchona ledgeriana Moens is an industrial plant producing secondary metabolite quinoline alkaloids. To maintain and moreover, to increase the quinoline production especially quinine, in vitro culture system through cell culture could be a potential ...
Maulidiyah Utami, Diah Ratnadewi, Dyah Iswantini, Trivadila   +3 more
doaj   +1 more source

In vitro and in vivo cancer cell apoptosis triggered by competitive binding of Cinchona alkaloids to the RING domain of TRAF6

Bioscience, biotechnology and biochemistry, 2019
TRAF6 is highly expressed in many tumors and plays an important role in the immune system. The aim of this study is to confirm anti-tumor activities of all naturally occurring Cinchona alkaloids that have been screened using computational docking program,
Yonghao Qi, Xuan Zhao, Jiaying Chen, A. Pradipta, Jing Wei, Haihua Ruan, Lijun Zhou, R. Hsung, Katsunori Tanaka   +8 more
semanticscholar   +1 more source

CARACTERIZACIÓN TAXONÓMICA Y FITOQUÍMICA DE Cinchona pubescens Y Ladenbergia oblongifolia EN EL ÁMBITO DEL VALLE ALTO HUALLAGA – REGIÓN HUÁNUCO

REBIOL, 2021
La familia Rubiaceae presenta especies que contienen alcaloides en la corteza, raíces, hojas, flores, frutos, semillas y polen. Muchas especies del género Cinchona y Ladenbergia, son fuentes de quina, remedio de origen natural para controlar la malaria ...
John R. Remuzgo Foronda, Jorge B. Alvarez Melo, Francisco Sales Dávila, Glauco Valdivieso Arenas   +3 more
doaj  

Smallholder farmers’ knowledge on management of Cinchona in the Democratic Republic of the Congo [PDF]

Plant Ecology and Evolution
Background and aims – Cinchona (Rubiaceae) tree bark is the key source of quinine alkaloids used as malaria treatment. Cinchona trees were introduced to Democratic Republic of the Congo (DRC) in the early 20th century. Currently, the eastern DRC accounts
Bezawit Mekonnen, Landry Cizungu, Julio Alegre, Haben Blondeel, Emiel De Lombaerde, Hans Verbeeck, Luc Duchateau, Eddie Schrevens, Kris Verheyen, Pascal Boeckx, Pieter De Frenne   +10 more
doaj   +3 more sources

Organocatalysis in total synthesis [PDF]

, 2015
Peer ...
Herrera, Raquel P., Marqués-López, Eugenia   +1 more
core   +2 more sources

Enhanced Production Level of Quinine in Cell Suspension Culture of Cinchona ledgeriana Moens by Paclobutrazol

Biotropia: The Southeast Asian Journal of Tropical Biology, 2013
Quinine is one of the major alkaloids in Cinchona spp., and it is used both as a medication and as a drink additive. The plant produces most of its alkaloids in the bark after 6–8 years of age.Repeated harvests can be performed until the plant dies ...
Diah Ratnadewi
doaj   +1 more source

The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio, René Slot Bitsch, Karl Anker Jørgensen   +2 more
wiley   +2 more sources

Vibrational Spectroscopic Study of the Cocrystal Products Formed by Cinchona Alkaloids with 5-Nitrobarbituric Acid

Journal of Spectroscopy, 2015
X-ray powder diffraction, differential scanning calorimetry, infrared absorption spectroscopy, and Raman spectroscopy have been used to study the phenomenon of cocrystal formation in the molecular complexes formed by 5-nitrobarbituric acid with four ...
Harry G. Brittain
doaj   +1 more source

Quinina: 470 anos de história, controvérsias e desenvolvimento Quinine: 470 years of history, controversy and science development

Química Nova, 2009
After 470 years, a history of development, international seed smuggling and scientific development that caused deep changes in our society, has reached an end. In 1638, the countess of Chinchón contracted a disease while in the Amazon rain forest and was
Alfredo Ricardo Marques de Oliveira, Daiane Szczerbowski   +1 more
doaj   +1 more source

COVID-19, Chloroquine Repurposing, and Cardiac Safety Concern: Chirality Might Help

Molecules, 2020
The desperate need to find drugs for COVID-19 has indicated repurposing strategies as our quickest way to obtain efficacious medicines. One of the options under investigation is the old antimalarial drug, chloroquine, and its analog, hydroxychloroquine ...
Giovanni Lentini, Maria Maddalena Cavalluzzi, Solomon Habtemariam   +2 more
doaj   +1 more source