Results 1 to 10 of about 396,990 (333)
Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae
Cells, 2021 Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require ...
Shital Kumar Mishra +2 more
doaj +1 more source
Effect of Dupilumab on Sleep Apnea Severity in Patients With Chronic Rhinosinusitis [PDF]
Sleep Medicine Research, 2023 Patients with chronic rhinosinusitis (CRS) report improved sleep quality after dupilumab, an anti IL4/13 therapy. Concurrent CRS and obstructive sleep apnea (OSA) cases are not rare, and CRS seemingly raises nasal resistance.
Sang-Wook Kim +10 more
doaj +1 more source
Age-related changes in circadian regulation of the human plasma lipidome
Communications Biology, 2023 Aging alters the amplitude and phase of centrally regulated circadian rhythms. Here we evaluate whether peripheral circadian rhythmicity in the plasma lipidome is altered by aging through retrospective lipidomics analysis on plasma samples collected in ...
Shadab A. Rahman +11 more
doaj +1 more source
Nature Communications, 2022 A key property of circadian rhythms is that they can be reset in response to environmental time cues; this response is described by a Phase Response Curve (PRC).
Brianne A. Kent +6 more
doaj +1 more source
Computational Analysis Predicts Hundreds of Coding lncRNAs in Zebrafish
Biology, 2021 Recent studies have demonstrated that numerous long noncoding RNAs (ncRNAs having more than 200 nucleotide base pairs (lncRNAs)) actually encode functional micropeptides, which likely represents the next regulatory biology frontier.
Shital Kumar Mishra, Han Wang
doaj +1 more source
Detection of neuronal OFF periods as low amplitude neural activity segments
BMC Neuroscience, 2023 Background During non-rapid eye movement sleep (NREM), alternating periods of synchronised high (ON period) and low (OFF period) neuronal activity are associated with high amplitude delta band (0.5–4 Hz) oscillations in neocortical electrophysiological ...
Christian D. Harding +6 more
doaj +1 more source
Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice
Nature Communications, 2021 Sleep pressure and circadian rhythms influence one another. However, the regulatory mechanisms are unclear. Here, the authors show that adenosine A1/A2A receptor antagonists, such as caffeine, shift circadian rhythms and enhance the effects of light ...
Aarti Jagannath +20 more
doaj +1 more source
NREM Parasomnias: Retrospective Analysis of Treatment Approaches and Comorbidities
Clocks & Sleep, 2022 The aim of this retrospective analysis is to determine the most frequently prescribed medications for the treatment of NREM parasomnias and evaluate reported outcomes.
Naina Limbekar +6 more
doaj +1 more source
Circadian disturbances and frailty risk in older adults
Nature Communications, 2023 Frailty is characterized by diminished resilience to stressor events. It is associated with adverse future health outcomes and impedes healthy aging.
Ruixue Cai +8 more
doaj +1 more source
BMJ Medicine, 2023 Objective To determine whether long weekly work hours and shifts of extended duration (≥24 hours) are associated with adverse patient and physician safety outcomes in more senior resident physicians (postgraduate year 2 and above; PGY2+).Design ...
Christopher P Landrigan +5 more
doaj +1 more source