Results 11 to 20 of about 178,041 (266)

Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae

Cells, 2021
Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require ...
Shital Kumar Mishra, Zhaomin Zhong, Han Wang   +2 more
doaj   +1 more source

Effect of Dupilumab on Sleep Apnea Severity in Patients With Chronic Rhinosinusitis [PDF]

Sleep Medicine Research, 2023
Patients with chronic rhinosinusitis (CRS) report improved sleep quality after dupilumab, an anti IL4/13 therapy. Concurrent CRS and obstructive sleep apnea (OSA) cases are not rare, and CRS seemingly raises nasal resistance.
Sang-Wook Kim, Scott A. Sands, Daniel Vena, Lauren B. Hess, Nicole A. Calianese, Robert James Konefal, Luigi Taranto-Montemurro, Ali Azarbarzin, Charles A. Czeisler, Tanya M. Laidlaw, Andrew Wellman   +10 more
doaj   +1 more source

Circadian rhythms [PDF]

Current Opinion in Neurobiology, 1993
The neurobiological substratum of circadian rhythmicity encompasses three levels of integration: firstly, generation of time signals by circadian pacemakers; secondly, entrainment of pacemakers by environmental influences; thirdly, coupling of circadian pacemakers among themselves and with target systems responsible for the expression of overt rhythms.
Aronson, B. D., Bell-Pederson, D., Block, G. D., Bos, N. P. A., Dunlap, J. C., Eskin, A., Garceau, N. Y., Geusz, M. E., Johnson, K. A., Khalsa, S. B. S., Koster-Van Hoffen, G. C., Koumenis, C., Lee, Theresa M., LeSauter, J., Lindgren, K. M., Liu, Qiuyun, Ruby, N. F., Silver, Rae, Turek, F. W., Zatz, M., Zucker, Irving   +20 more
openaire   +5 more sources

Age-related changes in circadian regulation of the human plasma lipidome

Communications Biology, 2023
Aging alters the amplitude and phase of centrally regulated circadian rhythms. Here we evaluate whether peripheral circadian rhythmicity in the plasma lipidome is altered by aging through retrospective lipidomics analysis on plasma samples collected in ...
Shadab A. Rahman, Rose M. Gathungu, Vasant R. Marur, Melissa A. St. Hilaire, Karine Scheuermaier, Marina Belenky, Jackson S. Struble, Charles A. Czeisler, Steven W. Lockley, Elizabeth B. Klerman, Jeanne F. Duffy, Bruce S. Kristal   +11 more
doaj   +1 more source

Circadian desynchronization [PDF]

Interface Focus, 2010
Abstract The suprachiasmatic nucleus (SCN) coordinates via multiple outputs physiological and behavioural circadian rhythms. The SCN is composed of a heterogeneous network of coupled oscillators that entrain to the daily light–dark cycles.
Adrián E, Granada, Trinitat, Cambras, Antoni, Díez-Noguera, Hanspeter, Herzel   +3 more
openaire   +2 more sources

Circadian lipid and hepatic protein rhythms shift with a phase response curve different than melatonin

Nature Communications, 2022
A key property of circadian rhythms is that they can be reset in response to environmental time cues; this response is described by a Phase Response Curve (PRC).
Brianne A. Kent, Shadab A. Rahman, Melissa A. St. Hilaire, Leilah K. Grant, Melanie Rüger, Charles A. Czeisler, Steven W. Lockley   +6 more
doaj   +1 more source

Computational Analysis Predicts Hundreds of Coding lncRNAs in Zebrafish

Biology, 2021
Recent studies have demonstrated that numerous long noncoding RNAs (ncRNAs having more than 200 nucleotide base pairs (lncRNAs)) actually encode functional micropeptides, which likely represents the next regulatory biology frontier.
Shital Kumar Mishra, Han Wang
doaj   +1 more source

Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice

Nature Communications, 2021
Sleep pressure and circadian rhythms influence one another. However, the regulatory mechanisms are unclear. Here, the authors show that adenosine A1/A2A receptor antagonists, such as caffeine, shift circadian rhythms and enhance the effects of light ...
Aarti Jagannath, Norbert Varga, Robert Dallmann, Gianpaolo Rando, Pauline Gosselin, Farid Ebrahimjee, Lewis Taylor, Dragos Mosneagu, Jakub Stefaniak, Steven Walsh, Teele Palumaa, Simona Di Pretoro, Harshmeena Sanghani, Zeinab Wakaf, Grant C. Churchill, Antony Galione, Stuart N. Peirson, Detlev Boison, Steven A. Brown, Russell G. Foster, Sridhar R. Vasudevan   +20 more
doaj   +1 more source

Detection of neuronal OFF periods as low amplitude neural activity segments

BMC Neuroscience, 2023
Background During non-rapid eye movement sleep (NREM), alternating periods of synchronised high (ON period) and low (OFF period) neuronal activity are associated with high amplitude delta band (0.5–4 Hz) oscillations in neocortical electrophysiological ...
Christian D. Harding, Mathilde C. C. Guillaumin, Lukas B. Krone, Martin C. Kahn, Cristina Blanco-Duque, Christian Mikutta, Vladyslav V. Vyazovskiy   +6 more
doaj   +1 more source

NREM Parasomnias: Retrospective Analysis of Treatment Approaches and Comorbidities

Clocks & Sleep, 2022
The aim of this retrospective analysis is to determine the most frequently prescribed medications for the treatment of NREM parasomnias and evaluate reported outcomes.
Naina Limbekar, Jonathan Pham, Rohit Budhiraja, Sogol Javaheri, Lawrence J. Epstein, Salma Batool-Anwar, Milena Pavlova   +6 more
doaj   +1 more source