Results 11 to 20 of about 376,159 (303)
Circadian disturbances and frailty risk in older adults
Nature Communications, 2023 Frailty is characterized by diminished resilience to stressor events. It is associated with adverse future health outcomes and impedes healthy aging.
Ruixue Cai +8 more
doaj +1 more source
Circadian clocks and breast cancer [PDF]
, 2016 Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic expression of numerous genes.
Blakeman, V +3 more
core +2 more sources
Biomolecular Concepts, 2014 Abstract Daily rhythms of light/darkness, activity/rest and feeding/fasting are important in human physiology and their disruption (for example by frequent changes between day and night shifts) increases the risk of disease. Many of the diseases found to be associated with such disrupted circadian lifestyles, including cancer ...
Jensen Lasse Dahl +2 more
openaire +3 more sources
Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]
, 2018 Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco +3 more
core +1 more source
BMJ Medicine, 2023 Objective To determine whether long weekly work hours and shifts of extended duration (≥24 hours) are associated with adverse patient and physician safety outcomes in more senior resident physicians (postgraduate year 2 and above; PGY2+).Design ...
Christopher P Landrigan +5 more
doaj +1 more source
The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism [PDF]
, 2015 The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer ...
Arble, Deanna M. +10 more
core +2 more sources
Environmental Circadian Disruption Elevates the IL-6 Response to Lipopolysaccharide in Blood [PDF]
, 2013 The immune system is regulated by circadian clocks within the brain and immune cells. Environmental circadian disruption (ECD), consisting of a 6-h phase advance of the light:dark cycle once a week for 4 weeks, elevates the inflammatory response to ...
Adams, Kandis L. +3 more
core +2 more sources
IEEE Photonics Journal, 2018 It has been elucidated that the responses to light by the human eye influence not only color and brightness recognition but also physiological aspects such as hormones. Melatonin, which affects human circadian rhythms, is sensitive to the blue wavelength
Changwook Kim +3 more
doaj +1 more source
Endocrinology, Diabetes & Metabolism, 2021 Background Melatonin is a hormone secreted by the pineal gland in a circadian rhythmic manner with peak synthesis at night. Melatonin signalling was suggested to play a critical role in metabolism during the circadian disruption.
Cynthia Tchio +3 more
doaj +1 more source
Genetic basis of human circadian rhythm disorders. [PDF]
, 2013 Circadian rhythm disorders constitute a group of phenotypes that usually present as altered sleep-wake schedules. Until a human genetics approach was applied to investigate these traits, the genetic components regulating human circadian rhythm and sleep ...
Fu, Ying-Hui +3 more
core +2 more sources