Results 31 to 40 of about 396,990 (333)
The retinal ipRGC-preoptic circuit mediates the acute effect of light on sleep
Nature Communications, 2021 The preoptic area (POA) is critical for sleep regulation but its role in acute, non-circadian, light effects on sleep are unclear. The authors show that intrinsically photosensitive retinal ganglion cells provide substantial input into the POA and ...
Ze Zhang +3 more
doaj +1 more source
Environmental Circadian Disruption Elevates the IL-6 Response to Lipopolysaccharide in Blood [PDF]
, 2013 The immune system is regulated by circadian clocks within the brain and immune cells. Environmental circadian disruption (ECD), consisting of a 6-h phase advance of the light:dark cycle once a week for 4 weeks, elevates the inflammatory response to ...
Adams, Kandis L. +3 more
core +2 more sources
Chronotype and self-reported sleep, alertness, and mental health in U.S. sailors
Military Medical Research, 2021 Service members are at risk for sleep and psychological conditions affecting their readiness. Chronotype (“morningness” or “eveningness”) is strongly associated with sleep, health and performance.
Elizabeth M. Harrison +4 more
doaj +1 more source
Clocks & Sleep, 2023 The main aim of this study was to explore how melatonin onset timing and phase angle to bedtime in healthy older adults are impacted by prior light exposure.
Arturo Arrona-Palacios +3 more
doaj +1 more source
Making Memories: Why Time Matters [PDF]
, 2018 In the last decade advances in human neuroscience have identified the critical importance of time in creating long-term memories. Circadian neuroscience has established biological time functions via cellular clocks regulated by photosensitive retinal ...
Evans, M. D. R. +2 more
core +2 more sources
Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]
, 2015 Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C +2 more
core +1 more source
Wellcome Open Research, 2017 Background: Disruption of rhythms in activity and rest occur in many diseases, and provide an important indicator of healthy physiology and behaviour. However, outside the field of sleep and circadian rhythm research, these rhythmic processes are rarely ...
Laurence A. Brown +3 more
doaj +1 more source
Extraordinary behavioral entrainment following circadian rhythm bifurcation in mice. [PDF]
, 2016 The mammalian circadian timing system uses light to synchronize endogenously generated rhythms with the environmental day. Entrainment to schedules that deviate significantly from 24 h (T24) has been viewed as unlikely because the circadian pacemaker ...
Gorman, Michael R +5 more
core +2 more sources
NREM delta power and AD-relevant tauopathy are associated with shared cortical gene networks
Scientific Reports, 2021 Reduced NREM sleep in humans is associated with AD neuropathology. Recent work has demonstrated a reduction in NREM sleep in preclinical AD, pointing to its potential utility as an early marker of dementia.
Joseph R. Scarpa +5 more
doaj +1 more source
Mutation of Arabidopsis SPLICEOSOMAL TIMEKEEPER LOCUS1 Causes Circadian Clock Defects [PDF]
, 2012 The circadian clock plays a crucial role in coordinating plant metabolic and physiological functions with predictable environmental variables, such as dusk and dawn, while also modulating responses to biotic and abiotic challenges.
Brown, John WS +5 more
core +1 more source