Results 1 to 10 of about 120,096 (334)

Circadian clock control of ribosome composition promotes rhythmic translation and termination fidelity. [PDF]

Cell Rep
Lamb TM, Castillo KD, Porter R, Wu C, Purvine SO, Best G, Zink E, Preh EO, Shen L, Sachs MS, Bell-Pedersen D.   +10 more
europepmc   +2 more sources

Mood phenotypes in rodent models with circadian disturbances

Neurobiology of Sleep and Circadian Rhythms, 2022
Many physiological functions with approximately 24-h rhythmicity (circadian rhythms) are generated by an internal time-measuring system of the circadian clock.
Kiyomichi Imamura, Toru Takumi
doaj   +1 more source

Circadian Biology: Clocks within Clocks [PDF]

Current Biology, 2005
A small cluster of approximately 20,000 neurons in the ventral hypothalamus provide the body with key time-keeping signals and drive circadian rhythms. This circadian clock exhibits surprisingly complex substructures, with inputs from the retina, and outputs to other brain structures.
Piggins, Hugh D., Loudon, Andrew
openaire   +2 more sources

Circadian Clocks: Translation Lost [PDF]

Current Biology, 2005
One of the big questions in biological rhythms research is how a stable and precise circa-24 hour oscillation is generated on the molecular level. While increasing complexity seemed to be the key, a recent report suggests that circa-24 hour rhythms can be generated by just four molecules incubated in a test tube.
Roenneberg, T, Merrow, M
openaire   +1 more source

NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators. [PDF]

PLoS Genetics, 2016
Heterodimers of CLOCK and BMAL1 are the major transcriptional activators of the mammalian circadian clock. Because the paralog NPAS2 can substitute for CLOCK in the suprachiasmatic nucleus (SCN), the master circadian pacemaker, CLOCK-deficient mice ...
Dominic Landgraf, Lexie L Wang, Tanja Diemer, David K Welsh   +3 more
doaj   +1 more source

Circadian clock: a regulator of the immunity in cancer

Cell Communication and Signaling, 2021
The circadian clock is an endogenous timekeeper system that controls and optimizes biological processes, which are consistent with a master circadian clock and peripheral clocks and are controlled by various genes.
Zhen Zhang, Puhua Zeng, Wenhui Gao, Qing Zhou, Ting Feng, Xuefei Tian   +5 more
doaj   +1 more source

Circadian clock—A promising scientific target in oral science

Frontiers in Physiology, 2022
The oral and maxillofacial organs play vital roles in chewing, maintaining facial beauty, and speaking. Almost all physiological processes display circadian rhythms that are driven by the circadian clock, allowing organisms to adapt to the changing ...
Guangxia Feng, Guangxia Feng, Jiajia Zhao, Jiajia Zhao, Jiajia Zhao, Jinfeng Peng, Jinfeng Peng, Beibei Luo, Beibei Luo, Jiaqi Zhang, Jiaqi Zhang, Lili Chen, Lili Chen, Lili Chen, Zhi Xu, Zhi Xu, Zhi Xu   +16 more
doaj   +1 more source

Silybin A enhances circadian clock by targeting CRY1 and disrupting its interaction with CLOCK

Pharmacological Research - Modern Chinese Medicine, 2022
Circadian clock governs a large array of physiological and metabolic functions. The amplitude decline of circadian rhythm is associated with various chronic diseases. However, few clock enhancing-molecules are known. CRY1 is one of the main components of
Weijie Bian, Weilin Zhang, Hao Liang, Xiaowen Xie, Luhua Lai   +4 more
doaj   +1 more source

Circadian Clock and Nutrition

Nutrients, 2023
Rhythmicity is a fundamental characteristic of every living organism [...]
openaire   +3 more sources

Dynamical analysis of the effects of circadian clock on the neurotransmitter dopamine

Mathematical Biosciences and Engineering, 2023
The circadian clock is an autonomous timing system that regulates the physiological and behavioral activities of organisms. Dopamine (DA) is an important neurotransmitter that is associated with many biological activities such as mood and movement ...
Ying Li , Zhao Zhao, Yuan-yuan Tan , Xue Wang   +3 more
doaj   +1 more source