FLOWERING LOCUS C -dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathways [PDF]
, 2006 Background The circadian system drives pervasive biological rhythms in plants. Circadian clocks integrate endogenous timing information with environmental signals, in order to match rhythmic outputs to the local day/night cycle.
Amasino, Richard M. +5 more
core +6 more sources
Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal [PDF]
, 2006 Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be dusrupted.
Ding, Jian M. +9 more
core +5 more sources
Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases [PDF]
Frontiers in Molecular Neuroscience, 2019 Circadian rhythms regulate many biological processes and play fundamental roles in behavior, physiology, and metabolism. Such periodicity is critical for homeostasis because disruption or misalignment of the intrinsic rhythms is associated with the onset
Hyo Kyeong Cha +4 more
doaj +2 more sources
Barley Hv CIRCADIAN CLOCK ASSOCIATED 1 and Hv PHOTOPERIOD H1 Are Circadian Regulators That Can Affect Circadian Rhythms in Arabidopsis. [PDF]
PLoS ONE, 2015 Circadian clocks regulate many aspects of plant physiology and development that contribute to essential agronomic traits. Circadian clocks contain transcriptional feedback loops that are thought to generate circadian timing.
Jelena Kusakina +7 more
doaj +8 more sources
Mood phenotypes in rodent models with circadian disturbances
Neurobiology of Sleep and Circadian Rhythms, 2022 Many physiological functions with approximately 24-h rhythmicity (circadian rhythms) are generated by an internal time-measuring system of the circadian clock.
Kiyomichi Imamura, Toru Takumi
doaj +1 more source
NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators. [PDF]
PLoS Genetics, 2016 Heterodimers of CLOCK and BMAL1 are the major transcriptional activators of the mammalian circadian clock. Because the paralog NPAS2 can substitute for CLOCK in the suprachiasmatic nucleus (SCN), the master circadian pacemaker, CLOCK-deficient mice ...
Dominic Landgraf +3 more
doaj +1 more source
Circadian clock—A promising scientific target in oral science
Frontiers in Physiology, 2022 The oral and maxillofacial organs play vital roles in chewing, maintaining facial beauty, and speaking. Almost all physiological processes display circadian rhythms that are driven by the circadian clock, allowing organisms to adapt to the changing ...
Guangxia Feng +16 more
doaj +1 more source
Circadian clock: a regulator of the immunity in cancer
Cell Communication and Signaling, 2021 The circadian clock is an endogenous timekeeper system that controls and optimizes biological processes, which are consistent with a master circadian clock and peripheral clocks and are controlled by various genes.
Zhen Zhang +5 more
doaj +1 more source
Silybin A enhances circadian clock by targeting CRY1 and disrupting its interaction with CLOCK
Pharmacological Research - Modern Chinese Medicine, 2022 Circadian clock governs a large array of physiological and metabolic functions. The amplitude decline of circadian rhythm is associated with various chronic diseases. However, few clock enhancing-molecules are known. CRY1 is one of the main components of
Weijie Bian +4 more
doaj +1 more source
Circadian control of interferon-sensitive gene expression in murine skin. [PDF]
, 2020 The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation.
Andersen, Bogi +9 more
core +2 more sources