Circadian control of interferon-sensitive gene expression in murine skin. [PDF]
, 2020 The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation.
Andersen, Bogi +9 more
core +2 more sources
Tuning up an aged clock: Circadian clock regulation in metabolism and aging
Translational Medicine of Aging, 2022 Circadian rhythms provide temporal variation of a broad range of behavioral and physiological functions, which is precisely controlled by the internal molecular gear, the circadian clock.
Shogo Sato +3 more
doaj +1 more source
Accurate timekeeping is controlled by a cycling activator in Arabidopsis. [PDF]
, 2013 Transcriptional feedback loops are key to circadian clock function in many organisms. Current models of the Arabidopsis circadian network consist of several coupled feedback loops composed almost exclusively of transcriptional repressors.
Devisetty, Upendra K +2 more
core +1 more source
Dynamical analysis of the effects of circadian clock on the neurotransmitter dopamine
Mathematical Biosciences and Engineering, 2023 The circadian clock is an autonomous timing system that regulates the physiological and behavioral activities of organisms. Dopamine (DA) is an important neurotransmitter that is associated with many biological activities such as mood and movement ...
Ying Li +3 more
doaj +1 more source
Rodent models for the analysis of tissue clock function in metabolic rhythms research [PDF]
, 2017 The circadian timing system consists on a distributed network of cellular clocks that together coordinate 24-h rhythms of physiology and behavior. Clock function and metabolism are tightly coupled, from the cellular to the organismal level.
Astiz, Mariana +3 more
core +2 more sources
Circadian Rhythms in the CNS and Peripheral Clock Disorders: The Circadian Clock and Hyperlipidemia
Journal of Pharmacological Sciences, 2007 A circadian clock controls various physiological and behavioral rhythms. In mammals, a master circadian clock exists in the suprachiasmatic nucleus of the hypothalamus, and slave oscillators can be found in most tissues.
Takashi Kudo +2 more
doaj +1 more source
Parallel analysis of Arabidopsis circadian clock mutants reveals different scales of transcriptome and proteome regulation [PDF]
Open Biology, 2017 The circadian clock regulates physiological processes central to growth and survival. To date, most plant circadian clock studies have relied on diurnal transcriptome changes to elucidate molecular connections between the circadian clock and observable ...
Alexander Graf +6 more
doaj +1 more source
Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]
, 2018 Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco +3 more
core +1 more source
Circadian rhythms in the absence of the clock gene Bmal1
Science, 2020 Redundancy in circadian clocks? The transcription factor BMAL1 is a core component of the mammalian circadian clock; without it, circadian behaviors are abolished. However, Ray et al.
Sandipan Ray +6 more
semanticscholar +1 more source
Crosstalk between the circadian clock and innate immunity in Arabidopsis. [PDF]
PLoS Pathogens, 2013 The circadian clock integrates temporal information with environmental cues in regulating plant development and physiology. Recently, the circadian clock has been shown to affect plant responses to biotic cues.
Chong Zhang +10 more
doaj +1 more source