Results 201 to 210 of about 109,508 (306)

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Circadian Clock: A Regulator of Immunity in Autoimmune Diseases. [PDF]

Immun Inflamm Dis
Wu YJ, Zhang SY, Chen HY, He XR, Yang GR.   +4 more
europepmc   +1 more source

CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine

Med Research, EarlyView.
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang, Suibi Yang, Jiajun Cai, Songzan Qian, Shuping Song, Jun Guo, Yang Wang, Jinyan Xing, Bo Zhang, Zhihao Wang, Shengze Wu, Xinhao Jin, Bowen Tan, Dongdong Yang, Yao Yan, Haoran Chen, Changlin Sun, Kang Zou, Yuxin Leng, Jingye Pan, Tianlong Zhang, Yiming Shao, Lina Xian, Hongjun Kang, Zhen Wang, Ruilan Wang, Nan Wang, Lvyin Yan, Kun Cheng, Songqiao Liu, Lin Chen, Caibao Hu, Fuhong Su, Qian Gao, Yi Yang, Zhongheng Zhang, On behalf of Chinese Multi‐omics Advances In Sepsis (CMAISE) Consortium   +36 more
wiley   +1 more source

Circadian clock genes and insomnia: molecular mechanisms and therapeutic implications. [PDF]

Ann Med
Ren Q, Gu M, Fan X.
europepmc   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Resveratrol and dexamethasone have cell-specific effects on the circadian clock but not on the rhythm of mitochondrial function in the fetal heart. [PDF]

J Physiol Biochem
Semenovykh D, Semenovykh K, Sládek M, Sumová A.   +3 more
europepmc   +1 more source

Regulatory mechanisms of reproduction in locusts and grasshoppers

New Plant Protection, EarlyView.
Regulatory networks composed of numerous coding and noncoding genes play crucial roles in the reproduction of locusts and grasshoppers. This review integrates mechanistic advances in reproductive regulation, highlighting environmentally adaptive pathways and providing prospective targets for eco‐friendly pesticides.
Jing He, Jiliang Wang, Xinran Wang
wiley   +1 more source

Loss of the liver circadian clock affects the expression of intrarenal renin-angiotensin system components. [PDF]

Sci Rep
Hassan SA, Stumpe M, Hui KY, Giraud MN, Albrecht U, Ripperger JA.   +5 more
europepmc   +1 more source

Defense heterosis as a novel plant protection strategy: From theory to breeding practice

New Plant Protection, EarlyView.
Defense heterosis, the enhanced disease resistance of hybrids compared to their parents, has evolved from early observations of hybrid vigor to a novel research concept. Advances are now clarifying its diverse genetic and molecular mechanisms across various plant–pathogen interactions.
Kaiqi Xu, Xue Li, Fangfang Li
wiley   +1 more source

Research progress on the mutual regulatory mechanism of circadian clock genes and autophagy. [PDF]

Front Cell Dev Biol
Ma Y, Yu R, Zheng X, Rao J, Shi G, Ding Y.   +5 more
europepmc   +1 more source