Results 201 to 210 of about 389,737 (359)
Circadian rhythmic kinase CK2α phosphorylates BMAL1 to regulate the mammalian clock [PDF]
Clock proteins govern circadian physiology and their function is regulated by a variety of signaling pathways. Here, we show that p45^PFK^, a previously reported circadian rhythmic kinase, corresponds to CK2[alpha].
Jun Hirayama+6 more
core
Abstract Background Restless Legs Syndrome (RLS) is a neurological disorder reported to be associated with impulsivity and impairments in interoception and emotional regulation. However, limited research has explored the combined influence of RLS severity, psychological factors, and chronotype on impulsive decision‐making and risk‐taking behavior in ...
Giacomo Carollo+5 more
wiley +1 more source
THE MAMMALIAN CIRCADIAN CLOCK: GENE REGULATORY NETWORK AND THEIR COMPUTER ANALYSIS
This paper presents the results of the reconstruction and analysis of gene regulatory network of the circadian clock in mammals. Application of graph theory methods makes it possible to analyze the structure of the gene network and identify the central ...
O. A. Podkolodnaya+2 more
doaj
Rest–Activity Disturbances Correlate with Core Features in Dementia with Lewy Bodies
Abstract Background Sleep–wake disturbances are a clinically important and poorly studied feature of dementia with Lewy bodies (DLB) due to the challenges of in‐laboratory polysomnography in this population. Objectives To compare rest–activity rhythms in DLB, Parkinson's disease (PD), and age‐matched controls using home‐based wrist actigraphy and ...
Jack Anderson+7 more
wiley +1 more source
ABSTRACT Background Thermoregulation is critical for preventing hyperthermia during physical activity. In Huntington's disease (HD), research on possible thermoregulatory alterations has received little attention. Objectives We aimed to investigate and compare skin temperature differences before and after exercise between HD patients and healthy ...
Lucía Simón‐Vicente+7 more
wiley +1 more source
Abstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well‐established therapy in advanced Parkinson's disease (PD) improving motor and non‐motor signs including sleep. The mechanisms of sleep improvement are insufficiently understood.
Julia Steinhardt+6 more
wiley +1 more source
Definition and Classification of Dystonia
Abstract Dystonia is a movement disorder with varied clinical features and diverse etiologies. Here we present a revision of the 2013 consensus definition and classification of dystonia in light of subsequent publications and experience with its application during the last decade.
Alberto Albanese+13 more
wiley +1 more source
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina+15 more
wiley +1 more source
This study investigates the photoperiod‐dependent effects of eight phenolic‐rich fruit extracts on postprandial blood triacylglyceride (TAG) levels and serum inflammatory markers in F344 rats, following an oral lipid tolerance test (OLTT) and a lipopolysaccharide (LPS)‐induced inflammatory challenge. Results showed that cherry and plum extracts reduced
Francesca Manocchio+6 more
wiley +1 more source
Nano‐biosensors offer real‐time monitoring of cognitive and emotional states through biomarkers like cortisol and dopamine. They enhance personalized learning, mental health interventions, and daily performance across sectors. Integrated into wearables and IoT, they promise a transformative impact while raising ethical, technological, and regulatory ...
Priscilla Adomako Gyasi+6 more
wiley +1 more source