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Circadian Clocks [PDF]

open access: yesCell, 2001
The circadian clock in all organisms is so intimately linked to light reception that it appears as if evolution has simply wired a timer into the mechanism that processes photic information. Several recent studies have provided new insights into the role of light input pathways in the circadian system of Arabidopsis.
Till Roenneberg, Martha Merrow
openaire   +4 more sources

NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators. [PDF]

open access: yesPLoS Genetics, 2016
Heterodimers of CLOCK and BMAL1 are the major transcriptional activators of the mammalian circadian clock. Because the paralog NPAS2 can substitute for CLOCK in the suprachiasmatic nucleus (SCN), the master circadian pacemaker, CLOCK-deficient mice ...
Dominic Landgraf   +3 more
doaj   +1 more source

The circadian clock and asthma [PDF]

open access: yesThorax, 2013
It is characteristic of asthma that symptoms worsen overnight, particularly in the early hours of the morning. Nocturnal symptoms in asthma are common and are an important indicator for escalation of treatment. An extensive body of research has demonstrated that nocturnal symptoms of cough and dyspnea are accompanied by circadian variations in airway ...
Durrington, Hannah J.   +3 more
openaire   +4 more sources

Circadian Biology: Clocks within Clocks [PDF]

open access: yesCurrent Biology, 2005
A small cluster of approximately 20,000 neurons in the ventral hypothalamus provide the body with key time-keeping signals and drive circadian rhythms. This circadian clock exhibits surprisingly complex substructures, with inputs from the retina, and outputs to other brain structures.
Piggins, Hugh D., Loudon, Andrew
openaire   +3 more sources

The Rice Circadian Clock Regulates Tiller Growth and Panicle Development Through Strigolactone Signaling and Sugar Sensing

open access: yesThe Plant Cell, 2020
The rice circadian clock integrates sugar signaling and regulates expression of strigolactone pathway genes to control tillering and panicle development.
F. Wang   +7 more
semanticscholar   +1 more source

Feeding and circadian clocks [PDF]

open access: yesReproduction Nutrition Development, 2006
The mammalian genome encodes at least a dozen of genes directly involved in the regulation of the feedback loops constituting the circadian clock. The circadian system is built up on a multitude of oscillators organized according to a hierarchical model in which neurons of the suprachiasmatic nuclei of the hypothalamus may drive the central circadian ...
Pardini, Lissia, Kaeffer, Bertrand
openaire   +3 more sources

Circadian clock: a regulator of the immunity in cancer

open access: yesCell Communication and Signaling, 2021
The circadian clock is an endogenous timekeeper system that controls and optimizes biological processes, which are consistent with a master circadian clock and peripheral clocks and are controlled by various genes.
Zhen Zhang   +5 more
doaj   +1 more source

Circadian clock—A promising scientific target in oral science

open access: yesFrontiers in Physiology, 2022
The oral and maxillofacial organs play vital roles in chewing, maintaining facial beauty, and speaking. Almost all physiological processes display circadian rhythms that are driven by the circadian clock, allowing organisms to adapt to the changing ...
Guangxia Feng   +16 more
doaj   +1 more source

The circadian clock of cyanobacteria [PDF]

open access: yesBioEssays, 2000
A circadian clock, with physiological characteristics similar to those of eukaryotes, functions in the photosynthetic prokaryote, cyanobacteria. The molecular mechanism of this clock has been efficiently dissected using a luciferase reporter gene that reports the status of the clock.
Masahiro Ishiura, Takao Kondo
openaire   +3 more sources

Circadian clocks in the ovary [PDF]

open access: yesTrends in Endocrinology & Metabolism, 2010
Clock gene expression has been observed in tissues of the hypothalamic-pituitary-gonadal (HPG) axis. Whereas the contribution of hypothalamic oscillators to the timing of reproductive biology is well known, the role of peripheral oscillators like those in the ovary is less clear.
Michael Menaker, Michael T. Sellix
openaire   +3 more sources

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