Results 31 to 40 of about 404,197 (358)
Cancer and the Circadian Clock.
Cancer Research, 2019 The circadian clock is a master regulator of mammalian physiology, regulating daily oscillations of crucial biological processes and behaviors. Notably, circadian disruption has recently been identified as an independent risk factor for cancer and ...
Ayesha A. Shafi, K. Knudsen
semanticscholar +1 more source
Biologia Plantarum, 2018 Strawberry is an economically important fruit crop worldwide. Circadian clock genes are endogenous timers that regulate a wide range of metabolic processes and consequently plant development.
X. D. Chen, J. Wang, M. Z. Zhao, F. Zhao
doaj +1 more source
Circadian Clock Genes and the Transcriptional Architecture of the Clock Mechanism.
Journal of Molecular Endocrinology, 2018 The mammalian circadian clock has evolved as an adaptation to the 24-hour light/dark cycle on earth. Maintaining cellular activities in synchrony with the activities of the organism (such as eating and sleeping) helps different tissue and organ systems ...
K. H. Cox, J. Takahashi
semanticscholar +1 more source
Environmental memory from a circadian oscillator:the Arabidopsis thaliana clock differentially integrates perception of photic vs. thermal entrainment [PDF]
, 2011 The constraint of a rotating earth has led to the evolution of a circadian clock that drives anticipation of future environmental changes. During this daily rotation, the circadian clock of Arabidopsis thaliana (Arabidopsis) intersects with the diurnal ...
Amanda M. Davis +8 more
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Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock.
Cancer Discovery, 2019 Glioblastomas are highly lethal cancers, containing self-renewing glioblastoma stem cells (GSCs). Here, we show that GSCs, differentiated glioblastoma cells (DGCs), and non-malignant brain cultures all displayed robust circadian rhythms, yet GSCs alone ...
Zhen Dong +19 more
semanticscholar +1 more source
Identification of PCBP1 as a Novel Modulator of Mammalian Circadian Clock
Frontiers in Genetics, 2021 The circadian clock governs our daily cycle of behavior and physiology. Previous studies have identified a handful of core clock components and hundreds of circadian modifiers.
Yaling Wu +11 more
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Quantitative analysis of regulatory flexibility under changing environmental conditions [PDF]
, 2010 The circadian clock controls 24-h rhythms in many biological processes, allowing appropriate timing of biological rhythms relative to dawn and dusk. Known clock circuits include multiple, interlocked feedback loops.
Adrian W Thomson +12 more
core +4 more sources
Circadian and Circalunar Clock Interactions in a Marine Annelid
Cell Reports, 2013 Life is controlled by multiple rhythms. Although the interaction of the daily (circadian) clock with environmental stimuli, such as light, is well documented, its relationship to endogenous clocks with other periods is little understood.
Juliane Zantke +8 more
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Circadian Clock Regulates Inflammation and the Development of Neurodegeneration
Frontiers in Cellular and Infection Microbiology, 2021 The circadian clock regulates numerous key physiological processes and maintains cellular, tissue, and systemic homeostasis. Disruption of circadian clock machinery influences key activities involved in immune response and brain function.
Xiao-Lan Wang, Lianjian Li, Lianjian Li
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Circadian clocks and breast cancer [PDF]
, 2016 Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic expression of numerous genes.
Blakeman, V +3 more
core +2 more sources