Results 41 to 50 of about 404,197 (358)

The role of circadian clock in astrocytes: From cellular functions to ischemic stroke therapeutic targets

open access: yesFrontiers in Neuroscience, 2022
Accumulating evidence suggests that astrocytes, the abundant cell type in the central nervous system (CNS), play a critical role in maintaining the immune response after cerebral infarction, regulating the blood-brain barrier (BBB), providing nutrients ...
Yuxing Zhang   +11 more
doaj   +1 more source

A bioinformatic analysis identifies circadian expression of splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line [PDF]

open access: yes, 2019
The circadian clock regulates key cellular processes and its dysregulation is associated to several pathologies including cancer. Although the transcriptional regulation of gene expression by the clock machinery is well described, the role of the clock ...
Abreu, Mónica   +4 more
core   +1 more source

Hypoxia induces a time- and tissue-specific response that elicits intertissue circadian clock misalignment

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Circadian clocks are present in most cells of the body and act in concert to coordinate our daily physiology and behavior with the environment.
Gal Manella   +6 more
semanticscholar   +1 more source

Circadian Rhythms in the CNS and Peripheral Clock Disorders: Role of the Biological Clock in Cardiovascular Diseases

open access: yesJournal of Pharmacological Sciences, 2007
The cardiovascular diseases are closely related to circadian rhythm, which is under the control of the biological clock. Clock genes show circadian oscillation not only in the suprachiasmatic nucleus but also in peripheral tissues, suggesting the ...
Koji Maemura   +2 more
doaj   +1 more source

The Modification of Circadian Clock Components in Soybean During Domestication and Improvement

open access: yesFrontiers in Genetics, 2020
Agricultural production is greatly dependent on daylength, which is determined by latitude. Living organisms align their physiology to daylength through the circadian clock, which is made up of input sensors, core and peripheral clock components, and ...
Man-Wah Li, Hon-Ming Lam, Hon-Ming Lam
doaj   +1 more source

p38 Mitogen-activated Protein Kinase Regulates Oscillation of Chick Pineal Circadian Clock [PDF]

open access: yes, 2003
Extracellular signal-regulated kinase (ERK) and p38 are members of the mitogen-activated protein kinase (MAPK) family, and in some cases these kinases serve for closely related cellular functions within a cell. In a wide range of animal clock structures,
Fukada, Yoshitaka   +4 more
core   +1 more source

Gut Microbiota-Derived Short Chain Fatty Acids Induce Circadian Clock Entrainment in Mouse Peripheral Tissue

open access: yesScientific Reports, 2018
Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the fermentation of non-digestible fibre can communicate from the microbiome to host tissues and modulate homeostasis in mammals.
Y. Tahara   +9 more
semanticscholar   +1 more source

Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]

open access: yes, 2015
Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C   +2 more
core   +1 more source

The choroid plexus is an important circadian clock component

open access: yesNature Communications, 2018
Mammalian circadian clocks have a hierarchical organization, governed by the suprachiasmatic nucleus (SCN) in the hypothalamus. The brain itself contains multiple loci that maintain autonomous circadian rhythmicity, but the contribution of the non-SCN ...
J. Myung   +10 more
semanticscholar   +1 more source

The contribution of circadian clock to the biological processes

open access: yesFrontiers in Molecular Biosciences
All organisms have various circadian, behavioral, and physiological 24-h periodic rhythms, which are controlled by the circadian clock. The circadian clock controls various behavioral and physiological rhythms.
Beibei Luo   +17 more
doaj   +1 more source

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