Results 41 to 50 of about 402,265 (407)

Circadian Organization in Hemimetabolous Insects [PDF]

open access: yes, 2004
The circadian system of hemimetabolous insects is reviewed in respect to the locus of the circadian clock and multioscillatory organization. Because of relatively easy access to the nervous system, the neuronal organization of the clock system in ...
Abe Y.   +17 more
core   +1 more source

Characterization and expression analysis of circadian clock genes in the diploid woodland strawberry Fragaria vesca

open access: yesBiologia Plantarum, 2018
Strawberry is an economically important fruit crop worldwide. Circadian clock genes are endogenous timers that regulate a wide range of metabolic processes and consequently plant development.
X. D. Chen, J. Wang, M. Z. Zhao, F. Zhao
doaj   +1 more source

Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period.

open access: yesPLoS Biology, 2020
A ubiquitous feature of the circadian clock across life forms is its organization as a network of cellular oscillators, with individual cellular oscillators within the network often exhibiting considerable heterogeneity in their intrinsic periods.
K L Nikhil, Sandra Korge, Achim Kramer
doaj   +1 more source

Circadian Clock Genes and the Transcriptional Architecture of the Clock Mechanism.

open access: yesJournal of Molecular Endocrinology, 2018
The mammalian circadian clock has evolved as an adaptation to the 24-hour light/dark cycle on earth. Maintaining cellular activities in synchrony with the activities of the organism (such as eating and sleeping) helps different tissue and organ systems ...
K. H. Cox, J. Takahashi
semanticscholar   +1 more source

Identification of PCBP1 as a Novel Modulator of Mammalian Circadian Clock

open access: yesFrontiers in Genetics, 2021
The circadian clock governs our daily cycle of behavior and physiology. Previous studies have identified a handful of core clock components and hundreds of circadian modifiers.
Yaling Wu   +11 more
doaj   +1 more source

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock.

open access: yesCancer Discovery, 2019
Glioblastomas are highly lethal cancers, containing self-renewing glioblastoma stem cells (GSCs). Here, we show that GSCs, differentiated glioblastoma cells (DGCs), and non-malignant brain cultures all displayed robust circadian rhythms, yet GSCs alone ...
Zhen Dong   +19 more
semanticscholar   +1 more source

The Circadian Clock in the Kidney [PDF]

open access: yesJournal of the American Society of Nephrology, 2011
Circadian variations in renal function were first described in the 19th century, and GFR, renal blood flow, urine production, and electrolyte excretion exhibit daily oscillations. These clinical observations are well established, but the underlying mechanisms that govern circadian fluctuations in kidney are not fully understood. Here we provide a brief
Michelle L. Gumz, Lisa R. Stow
openaire   +3 more sources

FLOWERING LOCUS C -dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathways [PDF]

open access: yes, 2006
Background The circadian system drives pervasive biological rhythms in plants. Circadian clocks integrate endogenous timing information with environmental signals, in order to match rhythmic outputs to the local day/night cycle.
Amasino, Richard M.   +5 more
core   +4 more sources

Circadian Clocks: Evolution in the Shadows [PDF]

open access: yesCurrent Biology, 2009
As scientists, we strive for highly controlled conditions. The real world, however, is noisy. Complex networks are a coping mechanism for an erratic environment.
Marc F.P.M. Maas, Martha Merrow
openaire   +4 more sources

Circadian Clock Regulates Inflammation and the Development of Neurodegeneration

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The circadian clock regulates numerous key physiological processes and maintains cellular, tissue, and systemic homeostasis. Disruption of circadian clock machinery influences key activities involved in immune response and brain function.
Xiao-Lan Wang, Lianjian Li, Lianjian Li
doaj   +1 more source

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