Results 51 to 60 of about 347,727 (386)
Kernel Architecture of the Genetic Circuitry of the Arabidopsis Circadian System [PDF]
PLoS Comput. Biol. 12, e1004748 (2016), 2016 A wide range of organisms features molecular machines, circadian clocks, which generate endogenous oscillations with ~24 h periodicity and thereby synchronize biological processes to diurnal environmental fluctuations. Recently, it has become clear that plants harbor more complex gene regulatory circuits within the core circadian clocks than other ...
arxiv +1 more source
Identification of PCBP1 as a Novel Modulator of Mammalian Circadian Clock
Frontiers in Genetics, 2021 The circadian clock governs our daily cycle of behavior and physiology. Previous studies have identified a handful of core clock components and hundreds of circadian modifiers.
Yaling Wu +11 more
doaj +1 more source
A Level Set Kalman Filter Approach to Estimate the Circadian Phase and its Uncertainty from Wearable Data [PDF]
arXiv, 2022 The circadian clock is an internal timer that coordinates the daily rhythms of behavior and physiology, including sleep and hormone secretion. Accurately tracking the state of the circadian clock, or circadian phase, holds immense potential for precision medicine. Wearable devices present an opportunity to estimate the circadian phase in the real world,
arxiv
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Circadian clocks are present in most cells of the body and act in concert to coordinate our daily physiology and behavior with the environment.
Gal Manella +6 more
semanticscholar +1 more source
The Circadian Clock in the Kidney [PDF]
Journal of the American Society of Nephrology, 2011 Circadian variations in renal function were first described in the 19th century, and GFR, renal blood flow, urine production, and electrolyte excretion exhibit daily oscillations. These clinical observations are well established, but the underlying mechanisms that govern circadian fluctuations in kidney are not fully understood. Here we provide a brief
Michelle L. Gumz, Lisa R. Stow
openaire +3 more sources
Circadian and Circalunar Clock Interactions in a Marine Annelid
Cell Reports, 2013 Life is controlled by multiple rhythms. Although the interaction of the daily (circadian) clock with environmental stimuli, such as light, is well documented, its relationship to endogenous clocks with other periods is little understood.
Juliane Zantke +8 more
doaj +1 more source
A minimal model of peripheral clocks reveals differential circadian re-entrainment in aging [PDF]
arXiv, 2022 The mammalian circadian system comprises a network of cell-autonomous oscillators, spanning from the central clock in the brain to peripheral clocks in other organs. These clocks are tightly coordinated to orchestrate rhythmic physiological and behavioral functions.
arxiv
Circadian Clock Proteins and Immunity [PDF]
Immunity, 2014 Immune parameters change with time of day and disruption of circadian rhythms has been linked to inflammatory pathologies. A circadian-clock-controlled immune system might allow an organism to anticipate daily changes in activity and feeding and the associated risk of infection or tissue damage to the host. Responses to bacteria have been shown to vary
Curtis A. M. +3 more
openaire +5 more sources
Frontiers in Neuroscience, 2022 Accumulating evidence suggests that astrocytes, the abundant cell type in the central nervous system (CNS), play a critical role in maintaining the immune response after cerebral infarction, regulating the blood-brain barrier (BBB), providing nutrients ...
Yuxing Zhang +11 more
doaj +1 more source
Scientific Reports, 2018 Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the fermentation of non-digestible fibre can communicate from the microbiome to host tissues and modulate homeostasis in mammals.
Y. Tahara +9 more
semanticscholar +1 more source