Results 121 to 130 of about 476,463 (387)

The genetics of circadian rhythms, sleep and health

Human Molecular Genetics, 2017
Circadian rhythms are 24-h rhythms in physiology and behaviour generated by molecular clocks, which serve to coordinate internal time with the external world.
A. Jagannath, Lewis Taylor, Zeinab Wakaf, S. Vasudevan, R. Foster   +4 more
semanticscholar   +1 more source

A Microfiber‐Reinforced Janus Hydrogel E‐Skin With Recyclable Feature for Multimodal Sensing and Gender‐Specific Physiological Monitoring

Advanced Science, EarlyView.
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding, Yufeng Li, Shaozhe Tan, Jiachun Sun, Xu Yang, Xuesi Zhang, Zhenhua Lin, Zhenyu Li, Yue Hao, Yannan Liu, Yingchun Li, Jingjing Chang   +11 more
wiley   +1 more source

Epigenetic Mechanisms in the Transcriptional Regulation of Circadian Rhythm in Mammals

Biology
Almost all organisms, from the simplest bacteria to advanced mammals, havea near 24 h circadian rhythm. Circadian rhythms are highly conserved across different life forms and are regulated by circadian genes as well as by related transcription factors ...
Wei Mao, Xingnan Ge, Qianping Chen, Jia-Da Li   +3 more
doaj   +1 more source

Rhythmic potassium transport regulates the circadian clock in human red blood cells

Nature Communications, 2017
Circadian rhythms usually rely on cyclic variations in gene expression. Red blood cells, however, display circadian rhythms while being devoid of nuclear DNA.
Erin A. Henslee, Priya Crosby, Stephen J. Kitcatt, Jack S. W. Parry, Andrea Bernardini, Rula G. Abdallat, Gabriella Braun, Henry O. Fatoyinbo, Esther J. Harrison, Rachel S. Edgar, Kai F. Hoettges, Akhilesh B. Reddy, Rita I. Jabr, Malcolm von Schantz, John S. O’Neill, Fatima H. Labeed   +15 more
doaj   +1 more source

Multivariate Contrastive Predictive Coding with Sliding Windows for Disease Prediction from Electronic Health Records

Advanced Intelligent Systems, EarlyView.
Adaptive multi‐indicator contrastive predictive coding is introduced as a self‐supervised pretraining framework for multivariate EHR time series. An adaptive sliding‐window algorithm and 2D convolutional neural network encoder capture localized temporal patterns and global indicator dependencies, enabling label‐efficient disease prediction that ...
Hongxu Yuan, Xiaozhu Jing, Yuzheng Yan, Wuman Luo   +3 more
wiley   +1 more source

Circadian Rhythms of the Liver and Their Sexual Dimorphism: Current State of the Problem

Инновационная медицина Кубани
The rhythmicity of life functioning processes at the cellular, organ, and system levels is one of the fundamental properties of living things. Among the wide range of biorhythms, circadian rhythms are the most important for mammals. In mammals, circadian
D. A. Areshidze, L. V. Kakturskiy
doaj   +1 more source

Circadian Regulation of Synaptic Plasticity

Biology, 2016
Circadian rhythms refer to oscillations in biological processes with a period of approximately 24 h. In addition to the sleep/wake cycle, there are circadian rhythms in metabolism, body temperature, hormone output, organ function and gene expression ...
Marcos G. Frank
doaj   +1 more source

Rodent models for the analysis of tissue clock function in metabolic rhythms research [PDF]

, 2017
The circadian timing system consists on a distributed network of cellular clocks that together coordinate 24-h rhythms of physiology and behavior. Clock function and metabolism are tightly coupled, from the cellular to the organismal level.
Astiz, Mariana, Leinweber, Brinja, Oster, Henrik, Tsang, Anthony H.   +3 more
core   +2 more sources

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

Annals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji, Christian J. Rampal, Esteban C. Rodríguez, Virginie Petel Légaré, Alexandra Lissouba, Sabrina Semmler, Meijiang Liao, Jay P. Ross, Guy A. Rouleau, Christine Vande Velde, Gary A.B. Armstrong   +10 more
wiley   +1 more source

Circadian rhythm and clinical characteristics in patients with acute myocardial infarction combined with obstructive sleep apnea

, 2022
Fang Zhao, Xiaoyun Zhao, Liheng Yang, Yuechuan Li   +3 more
openalex   +1 more source