Results 131 to 140 of about 213,878 (305)

Guided conjugate Bayesian clustering for uncovering rhythmically expressed genes [PDF]

, 2006
Background: An increasing number of microarray experiments produce time series of expression levels for many genes. Some recent clustering algorithms respect the time ordering of the data and are, importantly, extremely fast. The focus of this paper is
Millar, A. J., Smith, J. Q., Anderson, Paul E., Edwards, Kieron D.   +3 more
core  

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Circadian rhythms of macrophages are altered by the acidic tumor microenvironment

EMBO Reports
Tumor-associated macrophages (TAMs) are prime therapeutic targets due to their pro-tumorigenic functions, but varying efficacy of macrophage-targeting therapies highlights our incomplete understanding of how macrophages are regulated within the tumor ...
Amelia M Knudsen-Clark, Daniel Mwangi, Juliana Cazarin, Kristina Morris, Cameron Baker, Lauren M Hablitz, Matthew N McCall, Minsoo Kim, Brian J Altman   +8 more
doaj   +1 more source

Monitoring and assessment for obstructive sleep apnea

FlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu, Feifei Lin, Shujiao Chen, Zhen You, Shujing Zhu, Weiwei Zhao, Qiang Zhao   +6 more
wiley   +1 more source

Bio‐inspired vision: From principle, material architectures to system‐level integration

FlexMat, EarlyView.
This review introduces the development and mechanism of electronic and ionic bio‐inspired vision devices respectively. Then, it explores the impact of structure on bio‐inspired visual performance from the scale of intrinsic materials and device. Finally, it concludes that only by combining advanced software and technology can more complex vision ...
Zewan Lin, Miaoyi Xu, Xianda Ma, Weifeng Yang, Yuanlong Shao   +4 more
wiley   +1 more source

Potential bidirectional communication between the liver and the central circadian clock in MASLD

npj Metabolic Health and Disease
Most aspects of physiology and behaviour fluctuate every 24 h in mammals. These circadian rhythms are orchestrated by an autonomous central clock located in the suprachiasmatic nuclei that coordinates the timing of cellular clocks in tissues throughout ...
Frédéric Gachon, Elisabetta Bugianesi, Gabriele Castelnuovo, Henrik Oster, Julie S. Pendergast, Sara Montagnese   +5 more
doaj   +1 more source

Sympathetic NPY controls glucose homeostasis, cold tolerance, and cardiovascular functions in mice

Cell Reports
Summary: Neuropeptide Y (NPY) is best known for its effects in the brain as an orexigenic and anxiolytic agent and in reducing energy expenditure. NPY is also co-expressed with norepinephrine (NE) in sympathetic neurons.
Raniki Kumari, Raluca Pascalau, Hui Wang, Sheetal Bajpayi, Maria Yurgel, Kwaku Quansah, Samer Hattar, Emmanouil Tampakakis, Rejji Kuruvilla   +8 more
doaj   +1 more source

Spatiotemporal engineering of dynamic color in alternating‐current‐driven light‐emitting devices

FlexMat, EarlyView.
This review presents a mechanism‐driven framework for spectral tuning in alternating‐current‐driven light‐emitting devices, systematically integrating emissive center engineering, device architecture design, and driving signal modulation. By linking microscopic carrier dynamics and electric‐field‐charge interactions with macroscopic spectral evolution,
Yuyue Yang, Chenhao Li, Jinyang Li, Fanglong Yuan   +3 more
wiley   +1 more source

Circadian Rhythm

Journal of Investigative Dermatology, 1983
Rubin, Norma H., Scheving, Lawrence E.
openaire   +2 more sources