Results 181 to 190 of about 36,533 (268)

SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley   +1 more source

Functions and mechanisms of circular RNAs in cancer stem cells and therapy resistance. [PDF]

Front Cell Dev Biol
Yuan Y, Zhang D, Wang J, Jiang X, Duan L.   +4 more
europepmc   +1 more source

The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia

International Journal of Cancer, Volume 158, Issue 8, Page 2003-2012, 15 April 2026.
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch, Ana Carolina Rodrigues, Priscila Elias Ferreira Stricker, Alexandre Luiz Korte Azevedo, Daniel Pacheco Bruschi, Jaqueline Carvalho de Oliveira   +5 more
wiley   +1 more source

Circular RNA as emerging precision therapeutics: from RNA regulation to peptide translation. [PDF]

Precis Clin Med
Wu N, Amalraj J, Yang BB.
europepmc   +1 more source

Circular RNAs in cancer: Its biogenesis, functions, relationships with cancer progression, applications in immunotherapy and biomarker potentials. [PDF]

Cancer Immunol Immunother
Gao Y, Xu L, Sun R, Gao L, Yan P, Yang X, Wang G, Xian Y, Zhang J, Zhu D.   +9 more
europepmc   +1 more source

Synthetically designed circRNA can be used to target cardiovascular relevant microRNAs to improve cellular function. [PDF]

Sci Rep
Böttcher S, Kalies K, Knöpp K, Koch S, Pilowski C, Hüttelmaier S, Sedding D.   +6 more
europepmc   +1 more source

Discovery of novel circular RNAs of the apoptosis-related BAX gene in breast cancer, by combining nanopore and next-generation sequencing. [PDF]

Mol Genet Genomics
Katsaraki K, Vatsellas G, Kontos CK.
europepmc   +1 more source

Circular RNAs: An Under-Recognized Part in Different Scenarios of Host-Parasite Interrelationships. [PDF]

Pathogens
Sharaf MS, Ashour DS, Othman AA.
europepmc   +1 more source

A comprehensive landscape of the <i>Gossypium arboreum</i> circRNAome under multiple abiotic stresses. [PDF]

Front Plant Sci
Fei L, Zhou Y, Huang T, Wang K.
europepmc   +1 more source

Landscape of circular RNAs in acute myeloid leukemia and their clinical significance. [PDF]

NPJ Precis Oncol
Nguyen TH, Nguyen MH, Nguyen HN, Erkers T, Östling P, Bohlin A, Österroos A, Jafari R, Orre LM, Lehtiö J, Lehmann S, Kallioniemi O, Pawitan Y, Vu TN.   +13 more
europepmc   +1 more source