Results 211 to 220 of about 25,680 (233)
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Role of lncRNAs and circRNAs in epilepsy
Ageing Research Reviews, 2022Epilepsy is a chronic disorder of with a high prevalence and extensive health burden in almost all age groups of the population. This condition is resulted from disturbance in the balance between excitatory and inhibitory factors in the brain. Genetic elements that affect synaptic connectivity, receptors functions or ion channels have been shown to ...
Soudeh Ghafouri-Fard +5 more
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The new function of circRNA: translation
Clinical and Translational Oncology, 2020Circular RNAs (circRNAs) have been considered a special class of non-coding RNAs without 5' caps and 3' tails which are covalently closed RNA molecules generated by back splicing of mRNA. For a long time, circRNAs have been considered to be directly involved in various biological processes as functional RNA.
Y. Shi, X. Jia, J. Xu
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CircRNA Synthesis and Applications
Circular RNA (circRNA) is becoming an increasingly popular field of study and topic of interest. With that, there is a renewed and heightened interest in generating circular RNA for both research and clinical use. CircRNA generation began in the 1990s using in vitro chemical ligation and has since expanded out to include in vitro enzymatic synthesis ...Adam, Greasley +3 more
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CRISPR–Cas13 targets circRNAs
Nature Reviews Genetics, 2020The CRISPR–Cas13 system can be used to knock down circular RNAs (circRNAs) without any impact on related mRNAs, reports a study in Nature Methods.
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CircRNAs in cancer therapy tolerance
Clinica Chimica ActaThe rapidly expanding field of circular RNA (circ-RNA) research has opened new avenues in cancer diagnostics and treatment, highlighting the role of serum circRNAs as potential biomarkers for assessing tumor therapy resistance. This review comprehensively compiles existing knowledge regarding the biogenesis, function, and clinical relevance of circRNAs,
Miao He +3 more
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Emerging important roles of circRNAs in human cancer and other diseases
Genes and Diseases, 2021Cai Zhang, Huang Yong, Hongtao Ren
exaly
The roles of circRNAs in cancers: Perspectives from molecular functions
Gene, 2021Wei Liqing, Jin-Yu Sun
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CircRNAs in lung cancer - Biogenesis, function and clinical implication
Cancer Letters, 2020Weimin Li, Yong Peng, Chengdi Wang
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Emerging roles of circRNAs in leukemia and the clinical prospects: An update
Immunity, Inflammation and Disease, 2023exaly