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CircRNA Synthesis and Applications

Circular RNA (circRNA) is becoming an increasingly popular field of study and topic of interest. With that, there is a renewed and heightened interest in generating circular RNA for both research and clinical use. CircRNA generation began in the 1990s using in vitro chemical ligation and has since expanded out to include in vitro enzymatic synthesis ...
Adam, Greasley   +3 more
openaire   +2 more sources

CRISPR–Cas13 targets circRNAs

Nature Reviews Genetics, 2020
The CRISPR–Cas13 system can be used to knock down circular RNAs (circRNAs) without any impact on related mRNAs, reports a study in Nature Methods.
openaire   +2 more sources

CircRNAs in cancer therapy tolerance

Clinica Chimica Acta
The rapidly expanding field of circular RNA (circ-RNA) research has opened new avenues in cancer diagnostics and treatment, highlighting the role of serum circRNAs as potential biomarkers for assessing tumor therapy resistance. This review comprehensively compiles existing knowledge regarding the biogenesis, function, and clinical relevance of circRNAs,
Miao He   +3 more
openaire   +2 more sources

The emerging roles of circRNAs in cancer and oncology

Nature Reviews Clinical Oncology, 2021
Lasse Sommer Kristensen   +2 more
exaly  

Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities

Biochemical Pharmacology, 2022
Ali Vahabi   +2 more
exaly  

Emerging important roles of circRNAs in human cancer and other diseases

Genes and Diseases, 2021
Huang Yong, Cai Zhang, Jianli Xiong
exaly  

CircRNAs in lung cancer - Biogenesis, function and clinical implication

Cancer Letters, 2020
Chengdi Wang, Jingwei Li, Yong Peng
exaly  

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