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The expanding regulatory mechanisms and cellular functions of circular RNAs

Nature Reviews Molecular Cell Biology, 2020
Ling-Ling Chen, Chen Ling-Ling
exaly   +2 more sources

The biogenesis and emerging roles of circular RNAs

Nature Reviews Molecular Cell Biology, 2016
Ling-Ling Chen, Chen Ling-Ling
exaly   +2 more sources

Circular RNA Databases

2021
Circular RNAs (circRNAs) are a class of endogenous ncRNAs with covalently closed-loop structures, lacking of 5' caps and 3' tails. These novel ncRNAs are ubiquitously expressing in eukaryotes, exhibiting expression patterns of specific cell types, tissues, or developmental stages.
Peijing, Zhang, Ming, Chen
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Circular RNAs in cholangiocarcinoma

Cancer Letters, 2023
Cholangiocarcinoma (CCA) is the most common primary biliary malignancy with an adverse prognosis. Although its incidence is relatively low, early diagnosis is difficult due to the lack of specific symptoms. Current treatment options for CCA are limited, resulting in a low curative rate.
Wenwei Liao   +5 more
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Circular RNAs in atherosclerosis

Clinica Chimica Acta, 2022
Atherosclerosis (AS) is a chronic inflammatory lesion of the arterial vessel wall caused by a variety of complex factors. Furthermore, it is a major cause of cardiovascular disease and a leading cause of death. Circular RNAs (circRNAs) are a new family of endogenous non-coding RNAs with unique covalently closed loops that have sparked interest due to ...
Xiaoni, Huang   +3 more
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Circular RNA in Exosomes

2018
Circular RNAs (circRNAs) are a novel family of non-coding endogenous RNAs discovered in all eukaryotic cells and generated through a particular mechanism of alternative splicing called "back-splicing". These molecules show multiple functions, by acting as modulators of gene and miRNA expression, and may have a role in several biological processes, such
Daniele Fanale   +3 more
openaire   +3 more sources

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