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Nuclear export of circular RNA
NatureCircular RNAs (circRNAs), which are increasingly being implicated in a variety of functions in normal and cancerous cells1-5, are formed by back-splicing of precursor mRNAs in the nucleus6-10. circRNAs are predominantly localized in the cytoplasm, indicating that they must be exported from the nucleus.
Linh H. Ngo +15 more
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Circular RNAs: Characterization, cellular roles, and applications
Cell, 2022Ling-Ling Chen, Chu-Xiao Liu
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The expanding regulatory mechanisms and cellular functions of circular RNAs
Nature Reviews Molecular Cell Biology, 2020Ling-Ling Chen
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Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia
Cancer Cell, 2023Sheree Bailey +2 more
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The biogenesis and emerging roles of circular RNAs
Nature Reviews Molecular Cell Biology, 2016Ling-Ling Chen
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Circular RNAs: Biogenesis and Functions
Circular RNAs (circRNAs) are noncoding RNAs (ncRNAs) that show conservation across evolutionary lines and display specific expression patterns in tissues. They perform distinctive cellular roles and are promising biomarkers in therapeutic contexts. An ever-growing area of circRNA types and biological functions is closely related to recent advancements ...openaire +2 more sources
The Biogenesis, Functions, and Challenges of Circular RNAs
Molecular Cell, 2018Li Yang, Ling-Ling Chen
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Circular RNAs promote transcription
Nature Reviews Molecular Cell Biology, 2015Eytan Zlotorynski
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