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Circular RNAs in cholangiocarcinoma
Cancer Letters, 2023Cholangiocarcinoma (CCA) is the most common primary biliary malignancy with an adverse prognosis. Although its incidence is relatively low, early diagnosis is difficult due to the lack of specific symptoms. Current treatment options for CCA are limited, resulting in a low curative rate.
Wenwei Liao +5 more
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AtCircDB: a tissue-specific database for Arabidopsis circular RNAs
Briefings in Bioinformatics, 2019 © The Author 2017. Published by Oxford University Press. All rights reserved. Circular RNAs are widely existing in eukaryotes. However, there is as yet no tissue-specific Arabidopsis circular RNA database, which hinders the study of circular RNA in ...
Lin Wang, Hongwei Zhao, Xiaoyong Sun
exaly +2 more sources
2021
Circular RNAs (circRNAs) are a class of endogenous ncRNAs with covalently closed-loop structures, lacking of 5' caps and 3' tails. These novel ncRNAs are ubiquitously expressing in eukaryotes, exhibiting expression patterns of specific cell types, tissues, or developmental stages.
Peijing, Zhang, Ming, Chen
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Circular RNAs (circRNAs) are a class of endogenous ncRNAs with covalently closed-loop structures, lacking of 5' caps and 3' tails. These novel ncRNAs are ubiquitously expressing in eukaryotes, exhibiting expression patterns of specific cell types, tissues, or developmental stages.
Peijing, Zhang, Ming, Chen
openaire +2 more sources
Circular RNAs in atherosclerosis
Clinica Chimica Acta, 2022Atherosclerosis (AS) is a chronic inflammatory lesion of the arterial vessel wall caused by a variety of complex factors. Furthermore, it is a major cause of cardiovascular disease and a leading cause of death. Circular RNAs (circRNAs) are a new family of endogenous non-coding RNAs with unique covalently closed loops that have sparked interest due to ...
Xiaoni, Huang +3 more
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Cancer Letters, 2017
Circular RNAs (circRNAs) are a type of non-coding RNA molecules that lack a 5'-terminal cap and 3'-terminal poly A tail. A large number of circRNAs have been identified through biological experiments, computational methods and high-throughput sequencing. CircRNA sequence composition determines if a given circRNA is exonic, intronic or retained-intronic.
Jun He +4 more
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Circular RNAs (circRNAs) are a type of non-coding RNA molecules that lack a 5'-terminal cap and 3'-terminal poly A tail. A large number of circRNAs have been identified through biological experiments, computational methods and high-throughput sequencing. CircRNA sequence composition determines if a given circRNA is exonic, intronic or retained-intronic.
Jun He +4 more
openaire +2 more sources
2018
Circular RNAs (circRNAs) are a novel family of non-coding endogenous RNAs discovered in all eukaryotic cells and generated through a particular mechanism of alternative splicing called "back-splicing". These molecules show multiple functions, by acting as modulators of gene and miRNA expression, and may have a role in several biological processes, such
Daniele Fanale +3 more
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Circular RNAs (circRNAs) are a novel family of non-coding endogenous RNAs discovered in all eukaryotic cells and generated through a particular mechanism of alternative splicing called "back-splicing". These molecules show multiple functions, by acting as modulators of gene and miRNA expression, and may have a role in several biological processes, such
Daniele Fanale +3 more
openaire +3 more sources
2018
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for viroids in plants. Since then several additional types of circular RNAs in many species have been described such as the circular single-stranded ...
Nicole, Eger +4 more
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Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for viroids in plants. Since then several additional types of circular RNAs in many species have been described such as the circular single-stranded ...
Nicole, Eger +4 more
openaire +2 more sources
Role of circular RNAs in retinoblastoma
Functional & Integrative Genomics, 2022Retinoblastoma (RB), the most common malignant retinal tumor among children under 3 years old, is lethal if left untreated. Early diagnosis, together with timely and effective treatment, is important to improve retinoblastoma-related outcomes. Circular RNAs (circRNAs), a new class of non-coding RNAs with the capacity to regulate cellular activities ...
Fei, Li +4 more
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Characterization of Circular RNAs
2016Accumulated lines of evidence have revealed that a large number of circular RNAs are produced in transcriptomes from fruit fly to mouse and human. Unlike linear RNAs shaped with 5' cap and 3' tail, circular RNAs are characterized by covalently closed loop structures without open terminals, thus required specific treatments for their identification and ...
Yang, Zhang, Li, Yang, Ling-Ling, Chen
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Clinica Chimica Acta
Glioblastoma multiforme (GBM) is the most malignant and common form of brain cancer in adults. The molecular mechanisms underlying GBM progression and resistance are complex and poorly understood. Circular RNAs (circRNAs) are a new class of non-coding RNAsformed by covalently closed loopstructures with no free ends.
Elham, Ghadami +4 more
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Glioblastoma multiforme (GBM) is the most malignant and common form of brain cancer in adults. The molecular mechanisms underlying GBM progression and resistance are complex and poorly understood. Circular RNAs (circRNAs) are a new class of non-coding RNAsformed by covalently closed loopstructures with no free ends.
Elham, Ghadami +4 more
openaire +2 more sources