Results 1 to 10 of about 10,779,422 (268)

Single-photon microscopy to study biomolecular condensates

Nature Communications, 2023
Biomolecular condensates serve as membrane-less compartments within cells, concentrating proteins and nucleic acids to facilitate precise spatial and temporal orchestration of various biological processes.
Eleonora Perego, Sabrina Zappone, Francesco Castagnetti, Davide Mariani, Erika Vitiello, Jakob Rupert, Elsa Zacco, Gian Gaetano Tartaglia, Irene Bozzoni, Eli Slenders, Giuseppe Vicidomini   +10 more
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Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer

Non-Coding RNA, 2020
Hypoxia is dangerous for oxygen-dependent cells, therefore, physiological adaption to cellular hypoxic conditions is essential. The transcription factor hypoxia-inducible factor (HIF) is the main regulator of hypoxic metabolic adaption reducing oxygen ...
Dominik A. Barth, Felix Prinz, Julia Teppan, Katharina Jonas, Christiane Klec, Martin Pichler   +5 more
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Involvement of Long Non-Coding RNAs (lncRNAs) in Tumor Angiogenesis

Non-Coding RNA, 2020
Long non-coding RNAs (lncRNAs) are defined as non-protein coding transcripts with a minimal length of 200 nucleotides. They are involved in various biological processes such as cell differentiation, apoptosis, as well as in pathophysiological processes ...
Julia Teppan, Dominik A. Barth, Felix Prinz, Katharina Jonas, Martin Pichler, Christiane Klec   +5 more
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Non-Coding RNAs and SARS-Related Coronaviruses

Viruses, 2020
The emergence of SARS-CoV-2 in 2019 has caused a major health and economic crisis around the globe. Gaining knowledge about its attributes and interactions with human host cells is crucial.
Hanna Henzinger, Dominik A. Barth, Christiane Klec, Martin Pichler   +3 more
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The deleted in oral cancer (DOC1 aka CDK2AP1) tumor suppressor gene is downregulated in oral squamous cell carcinoma by multiple microRNAs

Cell Death and Disease, 2023
Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1; also known as deleted in oral cancer or DOC1) is a tumor suppressor gene known to play functional roles in both cell cycle regulation and in the epigenetic control of embryonic stem cell ...
Roberto Stabile, Mario Román Cabezas, Mathijs P. Verhagen, Francesco A. Tucci, Thierry P. P. van den Bosch, Maria J. De Herdt, Berdine van der Steen, Alex L. Nigg, Meng Chen, Cristina Ivan, Masayoshi Shimizu, Senada Koljenović, Jose A. Hardillo, C. Peter Verrijzer, Robert J. Baatenburg de Jong, George A. Calin, Riccardo Fodde   +16 more
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Pseudogenes, RNAs and new reproducibility norms

eLife, 2020
The partial success of a study to reproduce experiments that linked pseudogenes and cancer proves that understanding RNA networks is more complicated than expected.
George A Calin
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Multiomic analysis of HER2-enriched and AR-positive breast carcinoma with apocrine differentiation and an oligometastatic course: a case report

Frontiers in Oncology, 2023
Breast carcinoma is the most prevalent cancer among women globally. It has variable clinical courses depending on the stage and clinical-biological features.
Brando Poggiali, Agostino Ponzetti, Marica Malerba, Fabio Landuzzi, Federica Furia, Debora Charrance, Sara Trova, Vittoria Perseghin, Patrizia A. Falcone, Valentina Alliod, Alessandra Malossi, Pierpaolo Carassai, Ubaldo Familiari, Manuela Vecchi, Stefano Gustincich, Marina Schena, Andrea Cavalli, Andrea Cavalli, Alessandro Coppe   +18 more
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Epigenetic regulation in myocardial infarction: Non-coding RNAs and exosomal non-coding RNAs

Frontiers in Cardiovascular Medicine, 2022
Myocardial infarction (MI) is one of the leading causes of deaths globally. The early diagnosis of MI lowers the rate of subsequent complications and maximizes the benefits of cardiovascular interventions.
Sara Fadaei, Fatemeh Zarepour, Fatemeh Zarepour, Mehrnoosh Parvaresh, Alireza Motamedzadeh, Seyed Saeed Tamehri Zadeh, Amirhossein Sheida, Amirhossein Sheida, Mohammad Shabani, Mohammad Shabani, Michael R. Hamblin, Mehdi Rezaee, Maryam Zarei, Hamed Mirzaei   +13 more
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The gene regulatory role of non-coding RNAs in non-obstructive azoospermia

Frontiers in Endocrinology, 2022
Non-coding RNAs are classified as small non-coding RNAs, long non-coding RNAs and circular RNAs, which are involved in a variety of biological processes, including cell differentiation, proliferation, apoptosis and pathological conditions of various ...
Guanqing Zhou, Guanqing Zhou, Mimi Zhang, Mimi Zhang, Jingzhi Zhang, Jingzhi Zhang, Jingzhi Zhang, Yaofeng Feng, Zhishen Xie, Siyi Liu, Detu Zhu, Detu Zhu, Detu Zhu, Yumei Luo, Yumei Luo, Yumei Luo   +15 more
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Role of non-coding RNAs and exosomal non-coding RNAs in retinoblastoma progression

Frontiers in Cell and Developmental Biology, 2022
Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the potential to affect vision, and can even be fatal in some children.
Nasrin Ahangar Davoodi, Sajad Najafi, Zari Naderi Ghale-Noie, Ashkan Piranviseh, Samaneh Mollazadeh, Sahar Ahmadi Asouri, Zatollah Asemi, Mohammadamin Morshedi, Mohammadamin Morshedi, Seyed Saeed Tamehri Zadeh, Michael R. Hamblin, Amirhossein Sheida, Amirhossein Sheida, Hamed Mirzaei   +13 more
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