Results 11 to 20 of about 385,299 (305)
Non-coding RNAs Shaping Muscle [PDF]
Frontiers in Cell and Developmental Biology, 2020 In 1957, Francis Crick speculated that RNA, beyond its protein-coding capacity, could have its own function. Decade after decade, this theory was dramatically boosted by the discovery of new classes of non-coding RNAs (ncRNAs), including long ncRNAs ...
Julie Martone +3 more
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Role of non-coding RNAs and exosomal non-coding RNAs in retinoblastoma progression
Frontiers in Cell and Developmental Biology, 2022 Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the potential to affect vision, and can even be fatal in some children.
Nasrin Ahangar Davoodi +13 more
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Non-Coding RNAs in Retinoblastoma [PDF]
Frontiers in Genetics, 2019 Retinoblastoma (Rb) is the most common ocular pediatric malignancy that arises from the retina and is caused by a mutation of the two alleles of the tumor suppressor gene, RB1.
Meropi Plousiou, Ivan Vannini
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Non-coding RNAs and retroviruses [PDF]
Retrovirology, 2018 Retroviruses can cause severe diseases such as cancer and acquired immunodeficiency syndrome. A unique feature in the life cycle of retroviruses is that their RNA genome is reverse transcribed into double-stranded DNA, which then integrates into the host
Xu Zhang +4 more
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Non‐coding RNA and cholesteatoma [PDF]
Laryngoscope Investigative Otolaryngology, 2022 AbstractObjectiveCholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master regulators orchestrating disease progression are still unknown.
Ivan Jovanovic +3 more
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Human Molecular Genetics, 2006 The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a protein, but this does not mean that such RNAs do not contain information nor have function. Although it has been generally assumed that most genetic information is transacted by proteins, recent evidence suggests that the majority of the genomes of mammals and other ...
Mattick, John S., Makunin, Igor V.
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Non-coding RNA in cancer [PDF]
Essays in Biochemistry, 2021 Abstract Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, in this review, we mainly focus
Huiwen Yan, Pengcheng Bu
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Long Non-Coding RNA Epigenetics [PDF]
International Journal of Molecular Sciences, 2021 Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in ensuring cell functions and proper organism development by interacting with cellular compounds such as miRNA, mRNA, DNA and proteins. However, there is an additional level of lncRNA regulation, called lncRNA epigenetics, in gene expression control.
Marek Kazimierczyk, Jan Wrzesinski
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Non-coding RNA regulatory networks [PDF]
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 It is well established that the vast majority of human RNA transcripts do not encode for proteins and that non-coding RNAs regulate cell physiology and shape cellular functions. A subset of them is involved in gene regulation at different levels, from epigenetic gene silencing to post-transcriptional regulation of mRNA stability.
Panni S. +3 more
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