Results 1 to 10 of about 291,898 (269)
Frontiers in Cell and Developmental Biology, 2021 Purpose: Monocarboxylate transporter 4 (MCT4) can influence the amount of lactate in the tumor microenvironment and further control cancer cell proliferation, migration, and angiogenesis.
Athina Markou +6 more
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Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models [PDF]
Current Medicinal Chemistry, 2018, 2021 In the present review, we describe three hot topics in cancer research such as circulating tumor cells, exosomes, and 3D environment models. The first section is dedicated to microfluidic platforms for detecting circulating tumor cells, including both affinity based methods that take advantage of antibodies and aptamers, and label free approaches ...
arxiv +1 more source
Scientific Reports, 2023 Liquid biopsy (LB) provides a unique minimally invasive tool to follow-up cancer patients over time, to detect minimal residual disease (MRD), to study metastasis-biology and mechanisms of therapy-resistance.
Dimitra Stergiopoulou +8 more
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Biomedicines, 2022 The PD-1/PD-L1 axis provides CTCs an escape route from the immune system. Phosphorylation of the ribosomal protein S6 is implicated in the same pathway, following mTOR activation. The aim of the study was to investigate the expression of PD-L1 and pS6 in
Evangelia Pantazaka +6 more
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Scientific Reports, 2021 Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients under osimertinib.
Aliki Ntzifa +5 more
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The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
Frontiers in Endocrinology, 2022 Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene ...
JinHua He +8 more
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Algorithmic asymptotic analysis: extending the arsenal of cancer immunology modeling [PDF]
Journal of Theoretical Biology Volume 534, 7 February 2022, 110975, 2021 The recent advances in cancer immunotherapy boosted the development of tumor-immune system models aiming to provide mechanistic understanding and indicate more efficient treatment regimes. However, the complexity of such models, their multi-scale dynamics and their overparameterized character renders them inaccessible for wide utilization. In this work,
arxiv +1 more source
Technology in Cancer Research & Treatment, 2023 Study design Circulating tumor cells is important in the clinical diagnosis of cancer and there are a number of circulating tumor cell detection systems associated with different isolation strategies being validated.
Zhou-Fang Mei MD +7 more
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The Value of Circulating Tumor Cells in the Prognosis and Treatment of Pancreatic Cancer
Frontiers in Oncology, 2022 In the past few decades, tumor diagnosis and treatment theory have developed in a variety of directions. The number of people dying from pancreatic cancer increases while the mortality rate of other common tumors decreases.
Kai Luo +5 more
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Real-time stain-free classification of cancer cells and blood cells using interferometric phase microscopy and machine learning [PDF]
Cytometry A 99: 511-523, 2021, 2021 We present a method for a real time visualization and automatic processing for detection and classification of untouched cancer cells in blood during stain free imaging flow cytometry using digital holographic microscopy and machine learning in throughput of 15 cells per second.
arxiv +1 more source