Results 101 to 110 of about 461,371 (240)

SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities [PDF]

, 2019
Myeloid-derived suppressor cells (MDSC) are well-known key negative regulators of the immune response during tumor growth, however scattered is the knowledge of their capacity to influence and adapt to the different tumor microenvironments and of the ...
Botti L., Cappetti B., Chiodoni C., Colombo M. P., Consonni F. M., Gulino A., Nicola M. D., Portararo P., Randon G., Sangaletti S., Sica A., Talarico G., Tripodo C.   +12 more
core   +2 more sources

Circulating Tumor Cells in Melanoma Patients

PLoS ONE, 2012
Circulating tumor cells (CTCs) are of recognized importance for diagnosis and prognosis of cancer patients. With melanoma, most studies do not show any clear relationship between CTC levels and stage of disease. Here, CTCs were enriched (∼400X) from blood of melanoma patients using a simple centrifugation device (OncoQuick), and 4 melanocyte target ...
Rogerio I. Neves, Eric T. Kimchi, Susan D. Patrick, Ping Xin, Kevin F. Staveley-O'Carroll, Ramdane Harouaka, Gary A. Clawson, Siyang Zheng, Diane Thiboutot, Todd D. Schell, Arthur Berg, Paul J. Mosca   +11 more
openaire   +5 more sources

Circulating tumor cells and clusters as liquid biomarkers for the diagnosis and prognosis of neuroblastoma

BMC Cancer
Background The clinical significance of circulating tumor cell (CTC) clusters in highly metastatic tumors hasn’t yet been revealed. Here, we demonstrated the diagnostic and prognostic value of CTC clusters in neuroblastoma (NB) which is the most ...
Huanli Xu, Nianhua Cao, Wenyan Dai, Caiwei Sima, Meng Yi, Senmin Chen, Xiaowen Chen, Chao Liu, Uet Yu, Huiping Lang, Zhedie Zhou, Nanlin Yang, Chunjing Wang, Xianping Jiang, Yungen Gan, Jianyao Wang, Yuanxiang Wang, Nuaner Yao, Lidan Xiao, Qing Zhang, Junjie Sun, Zhou Lin, Gongwei Zhang, Jiayue Zhang, Hongtao Feng, Jianming Song, Sixi Liu, Zongbin Liu, Feiqiu Wen, Xiuli Yuan   +29 more
doaj   +1 more source

Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer. [PDF]

, 2014
BackgroundSipuleucel-T is a US Food and Drug Administration-approved immunotherapy for asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Its mechanism of action is not fully understood.
Amling, Christopher L, Carroll, Peter, Chan, Stephen, Corman, John, Fong, Lawrence, Frohlich, Mark W, Lewis, Jera, Sheikh, Nadeem A, Simko, Jeffrey, Sims, Robert B, Small, Eric J, Stephenson, Robert A, Weinberg, Vivian   +12 more
core   +2 more sources

Efficient presentation of tumor idiotype to autologous T cells by CD83+ dendritic cells derived from highly purified circulating CD14+ monocytes in multiple myeloma patients [PDF]

, 2000
Marina Ratta, Antonio Curti, Miriam Fogli, Mirko Pantucci, G.C. Viscomi, Pier Luigi Tazzari, Francesco Fagnoni, Rosanna Vescovini, Paolo Sansoni, S Tura, Roberto M. Lemoli   +10 more
openalex   +1 more source

Unmasking circulating tumor cells [PDF]

, 2016
The number of Circulating Tumor Cells (CTCs) that can be isolated from blood of cancer patients is prognostic for the course of the disease. A higher number of CTCs correlates with a worse prognosis. A change from a higher number to a lower number of CTCs indicates a benefit of the current treatment for the patient and vice versa.
openaire   +3 more sources

Cell-free circulating tumor DNA in cancer

Chinese Journal of Cancer, 2016
Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in
Zhen Qin, Vladimir A. Ljubimov, Cuiqi Zhou, Yunguang Tong, Jimin Liang   +4 more
doaj   +1 more source

Regulation of CD4+NKG2D+ Th1 cells in patients with metastatic melanoma treated with sorafenib : role of IL-15Rα and NKG2D triggering [PDF]

, 2014
Beyond cancer-cell intrinsic factors, the immune status of the host has a prognostic impact on patients with cancer and influences the effects of conventional chemotherapies.
Auperin, Anne, Ayyoub, Maha, Caignard, Anne, Caillat-Zucman, Sophie, Chaba, Kariman, Chaput, Nathalie, Dessen, Philippe, Eggermont, Alexander, Flament, Caroline, Jacquelot, Nicolas, Jacques, Yannick, Mateus, Christine, Messaoudene, Meriem, Mortier, Erwan, Poirier-Colame, Vichnou, Porta, Camillo, Robert, Caroline, Romero, Ana I., Rusakiewicz, Sylvie, Valmor, Danila, Vielh, Philippe, Zitvogel, Laurence   +21 more
core   +2 more sources

Alone you go faster, together you go farther

Molecular Oncology
The metastatic process is an extraordinarily complex step‐by‐step procedure, characterized by many analogies with migratory patterns of humans or animals across our planet. The ongoing interrogation of circulating tumor cells (CTCs), caught in the act of
Nicola Aceto
doaj   +1 more source

Deterministic Capture of Individual Circulating Tumor Cells Using a Flow-Restricted Microfluidic Trap Array

Micromachines, 2018
Circulating tumor cells (CTCs) are regarded as a strong biomarker which includes clinically valuable information. However, CTCs are very rare and require precise separation and detection for effective clinical applications.
Yousang Yoon, Jusin Lee, Ki-Chun Yoo, Onejae Sul, Su-Jae Lee, Seung-Beck Lee   +5 more
doaj   +1 more source