Results 111 to 120 of about 6,850,236 (255)

Implications of the hybrid epithelial/mesenchymal phenotype in metastasis

Frontiers in Oncology, 2015
Understanding cell-fate decisions during tumorigenesis and metastasis is a major challenge in modern cancer biology. One canonical cell-fate decision that cancer cells undergo is Epithelial-to-Mesenchymal Transition (EMT) and its reverse Mesenchymal-to ...
Mohit Kumar eJolly, Marcelo eBoareto, Bin eHuang, Dongya eJia, Mingyang eLu, José N Onuchic, Herbert eLevine, Eshel eBen-Jacob   +7 more
doaj   +1 more source

Additional file 10: of Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer

, 2018
Table S8. Complete blood counts in patients with single circulating tumor cells and circulating tumor cell clusters. The table shows complete blood counts in patients in whom only single circulating tumor cells (single CTC) or also clustered circulating ...
Viola Heinzelmann-Schwarz (390410), Barbara Szczerba (5997695), Walter Weber (5997716), Christoph Rochlitz (190083), Ramona Scherrer (5997704), Christian Kurzeder (5997713), Marcus Vetter (3422660), Alfred Zippelius (805066), Ilona Krol (5997701), Julia Landin (5997692), Cinzia Donato (5997698), Alexandra Malinovska (5997710), Sofia Gkountela (191896), Francesc Castro-Giner (5659600), Catharina Balmelli (5997707), Nicola Aceto (5997719)   +15 more
core   +1 more source

Spearman correlation for CCT2 tumor stain score, circulating tumor cell (CTC) count, and time gap.

, 2022
Spearman correlation for CCT2 tumor stain score, circulating tumor cell (CTC) count, and time gap.
Carlos Alemany (12937026), Elizabeth Griffith (1323738), Louis Barr (12937023), Annette R. Khaled (181666), Heba Ghozlan (10169090), Eunkyung Lee (1862767), Na’im Fanaian (8987786), S. A. Litherland (12937032), Amr S. Khaled (8987783), Xiang Zhu (135451), Amanda Cox (5073860), Rebecca Moroose (12937020), Ryan Sause (12937029), Ana Martini (12937017)   +13 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Defining Cell Cluster Size by Dielectrophoretic Capture at an Array of Wireless Electrodes of Several Distinct Lengths

Micromachines, 2019
Clusters of biological cells play an important role in normal and disease states, such as in the release of insulin from pancreatic islets and in the enhanced spread of cancer by clusters of circulating tumor cells.
Joseph T. Banovetz, Min Li, Darshna Pagariya, Sungu Kim, Baskar Ganapathysubramanian, Robbyn K. Anand   +5 more
doaj   +1 more source

Microfluidic cell isolation technology for drug testing of single tumor cells and their clusters [PDF]

, 2017
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the ...
Bithi, Swastika S., Vanapalli, Siva A.
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology
Tumor‐associated macrophages (TAMs) in brain tumors contain two types of macrophages: tumor‐associated microglia and infiltrating macrophages. This study explored whether these two populations have the same role in brain tumor progression. In an in vitro
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
doaj   +1 more source