Results 131 to 140 of about 6,225,689 (197)

Regulating chemoresistance and cancer stemness: the CDH17-YAP pathway in distinct cellular states of lung cancer CTC clusters

Cellular & Molecular Biology Letters
Background Drug resistance in metastatic lung cancer significantly contributes to patient mortality. This study explores the role of circulating tumor cells (CTCs), the precursors to metastasis, in driving this resistance.
Zujun Que, Dan Qi, Yun Yang, Wang Yao, Jiajun Liu, Yan Li, Yuanyuan Yu, Luyao Wang, Fangfei Li, Ge Zhang, Erxi Wu, Jianhui Tian   +11 more
doaj   +1 more source

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

Journal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo, Françoise Illien, Fabienne Burlina, Barbara Biondi   +3 more
wiley   +1 more source

Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients

Scientific Reports
Cell lines derived from circulating tumor cells (CTCs) in the blood provide important biological information on cancer metastasis. CTC-ITB-01 is a CTC cell line derived from a patient with metastatic estrogen receptor-alpha (ER-alpha) positive breast ...
Kai Bartkowiak, Parinaz Mossahebi Mohammadi, Paula Nissen, Stefan Werner, David Agorku, Antje Andreas, Maria Geffken, Sven Peine, Karl Verpoort, Thomas M. Deutsch, Laura L. Michel, Andreas Schneeweiss, Verena Thewes, Andreas Trumpp, Olaf Hardt, Volkmar Müller, Sabine Riethdorf, Hartmut Schlüter, Klaus Pantel   +18 more
doaj   +1 more source

Evaluation of triplet therapy combined with robot‐assisted cytoreductive prostatectomy for high‐volume metastatic prostate cancer: a multicentre randomised controlled trial protocol

BJU International, Volume 138, Issue 5, Page 807-814, November 2026.
Background Prostate cancer (PCa) is the second most common cancer in men. For patients with high‐volume metastatic PCa (mPCa) who are fit for docetaxel, a triplet therapy regimen consisting of androgen deprivation therapy (ADT), chemotherapy, and an androgen receptor pathway inhibitor (ARPI) is recommended.
Xiangwei Yang, Zhuobin He, Jian Chen, Hanqi Lei, Binyuan Yan, Linze Chen, Hong Liu, Jun Pang   +7 more
wiley   +1 more source

Circulating Tumor Cells

, 2018
Circulating tumor cells (CTC) play a central role in tumor dissemination and metastases, which are ultimately responsible for most cancer deaths. Technologies that allow for identification and enumeration of rare CTC from cancer patients’ blood have ...
Richard J. Cote, El-Ashry, Dorraya, Cote, Richard J, Agarwal, Ashutosh, Dorraya El-Ashry, Ashutosh Agarwal, Marija Balic, Balic, Marija   +7 more
core   +1 more source

Circulating Tumor Cells in Glioblastoma

Glioblastoma multiforme (GBM) remains a devastating brain tumor with poor prognosis, traditionally viewed as non-metastatic. The recent detection of circulating tumor cells (CTCs) in glioblastoma challenges this long-held view and opens new opportunities
Markus Schneemann, Robert H. Eibl
core   +1 more source

Performance comparison of streptavidin magnetic beads for epcam expressing cancer cell lines for circulating tumor cell (CTC) enrichment in a flow-through immunomagnetic system. [PDF]

PLoS One
Liu P, He S, Hart P, van Kleef A, Boxum S, Mentink A, Wu Y, Terstappen LWMM, Jonkheijm P, Stevens M.   +9 more
europepmc   +1 more source

Primary-Tumor Transcriptomic Signatures Associated with Circulating Tumor Cells Status in Breast Cancer: From CTC-Negative Remodeling to CTC-Associated Metastatic Programs. [PDF]

Biomedicines
Budak B, Ozay S, Yilmaz B, Arga KY.
europepmc   +1 more source

Clinical evaluation of size-based circulating tumor cell enumeration lab-on-a-disc

, 2015
Circulating tumor cell (CTC) is a critical component of metastasis. Here, we suggest a lab-on-a-disc for CTC enumeration from whole blood. The disc allows gentle yet efficient size-based filtration, achieving high recovery rate (95%) and log depletion of
Park, Juhee, Lim, Minji, Kim, Tae-Hyeong, Cho, Yoon-Kyoung   +3 more
core  

Clinical utility of circulating tumor-derived endothelial cells in lung cancer detection and prognosis prediction. [PDF]

Oncol Lett
Li X, Yang J, Chen B, Zhang Z, Zhao J, Zhao M, Wang Z.   +6 more
europepmc   +1 more source