Results 111 to 120 of about 6,225,689 (197)

Circulating and Disseminated Tumor Cells in the Management of Advanced Prostate Cancer

Advances in Urology, 2012
Management of prostate cancer is recognized as one of the most important medical problems. Latest findings concerning the role of circulating (CTC) and disseminated tumor cells (DTC) have provided new insights into the biology of metastasis with ...
Stephan Kruck, Georgios Gakis, Arnulf Stenzl   +2 more
doaj   +1 more source

Proteomic Analysis of Serum Extracellular Vesicles Revealed Fibulin‐3 as a Novel Predictive Biomarker for Hepatocellular Carcinoma in Patients With Chronic Hepatitis B

Hepatology Research, EarlyView.
We carried out proteomic analysis of serum extracellular vesicles to identify biomarkers predictive of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B receiving nucleos(t)ide analog therapy. Candidate proteins identified through proteomic analysis were subsequently quantified in serum by ELISA.
Emi Sometani, Kazuhiro Murai, Hayato Hikita, Jihyun Sung, Satoshi Muraoka, Hidenori Toyoda, Satoshi Tanaka, Takayuki Miyake, Shinji Kuriki, Kenji Fukumoto, Satoshi Shigeno, Yuta Myojin, Kazuki Maesaka, Kumiko Shirai, Yuki Makino, Yuki Tahata, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Jun Adachi, Tomomi Yamada, Tetsuo Takehara   +21 more
wiley   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Distribution of circulating tumor cell phenotype in early cervical cancer

Cancer Management and Research, 2019
Li Pan, Gaoshu Yan, Wenli Chen, Lei Sun, Jichuan Wang, Jialin YangRadiotherapy Department, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610041, People’s Republic of ...
Pan L, Yan G, Chen W, Sun L, Wang J, Yang J   +5 more
doaj  

microRNA‐145‐5p regulates P‐glycoprotein and breast cancer resistance protein in primary human fetal brain endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend Drug transporters P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) at the blood–brain barrier (BBB) protect the rapidly developing fetal brain. We investigated the role of microRNA‐145‐5p (miR‐145‐5p) microRNA (miRNA) in regulating these key transporters in primary human fetal brain endothelial cells in vitro. We
Phetcharawan Lye, Enrrico Bloise, Nikola Ivanovski, Lubna Nadeem, Christopher Casciaro, Stephen G. Matthews   +5 more
wiley   +1 more source

Abstract 1720: Circulating tumor cell (CTC) enrichment and DNA mutation detection by sequencing

, 2017
Molecular analysis of circulating tumor cells (CTCs) is hindered by low sensitivity and high level of background leukocytes of currently available CTC enrichment technologies.
Yixin Wang, Conrad Leung, Eric Zhao, Will Chow, Priya Gogoi, Ruqin Kou   +5 more
core   +1 more source

De‐Escalation of Neoadjuvant Treatment for HER2‐Positive Breast Cancer

International Journal of Cancer, Volume 159, Issue 10, Page 2393-2402, 15 November 2026.
ABSTRACT With improved prognosis in early HER2‐positive breast cancer, safely de‐escalating treatment is increasingly investigated to minimize overtreatment. This article focuses on neoadjuvant de‐escalation strategies for HER2‐positive breast cancer.
Yiyin Ma, Dedian Chen, Sheng Huang
wiley   +1 more source

Gastroesophageal circulating tumor cell crosstalk with peripheral immune system guides CTC survival and proliferation [PDF]

Tumor dissemination is a key event in tumor progression. During this event, a main role is played by circulating tumor cells (CTCs), immune cells, and their interaction.
Bandini, Erika, Gallerani, Giulia, Ivan Vannini, Michele Zanoni, Vannini, Ivan, Ilaria Pace, Cristian Bassi, Ferracin, Manuela, Chiara Arienti, Maurizio Puccetti, Milena Urbini, Pace, Ilaria, Massimo Negrini, Martina Valgiusti, Massimiliano Bonafè, Zanoni, Michele, Bonafé, Massimiliano, Angeli, Davide, Melloni, Mattia, Urbini, Milena, Miserocchi, Giacomo, Giulia Gallerani, Puccetti, Maurizio, Manuela Ferracin, Negrini, Massimo, Bassi, Cristian, Mattia Melloni, Arienti, Chiara, Tania Rossi, Giacomo Miserocchi, Rossi, Tania, Davide Angeli, Valgiusti, Martina, Erika Bandini   +33 more
core   +1 more source

Harnessing the Horse for Human Osteoarthritis: microRNA‐181a‐5p Antisense Oligonucleotides in Clinically Normal Equine Fetlock Joints Are Safe and Well Tolerated

Journal of Orthopaedic Research, Volume 44, Issue 11, November 2026.
ABSTRACT Horses serve as a translational model for human osteoarthritis (OA) due to their comparable joint size, cartilage thickness, and incidence of naturally occurring disease. Overexpression of microRNA‐181a‐5p has been implicated in cartilage degradation in OA, and its inhibition using locked nucleic acid antisense oligonucleotides (LNA‐miR‐181a ...
T. Connor McCorkell, Narman Mortagy, Rodrigo Munevar Luque, Thomas G. Koch, Janet Beeler‐Marfisi, Y. Raja Rampersaud, Jonathan Lamarre, Mohit Kapoor, Judith B. Koenig   +8 more
wiley   +1 more source

Development and verification of a three-dimensional (3D) breast cancer tumor model composed of circulating tumor cell (CTC) subsets

, 2019
Breast cancer is one of the most common cancer types among women in which early tumor invasion leads to metastases and death. EpCAM (epithelial cellular adhesion molecule) and HER2 (human epidermal growth factor receptor 2) are two main circulating tumor
Saglam-Metiner, Pelin, Kabak, Evrim Ceren, Anil-Inevi, Muge, Gulce-Iz, Sultan, 4. Kabak, Evrim Ceren, 5. Gülce İz, Sultan, 1. Anıl İnevi, Müge, 3. Sağlam Metiner, Pelin   +7 more
core   +1 more source