Results 101 to 110 of about 6,225,689 (197)
A scalable workflow for sensitive detection and genomic profiling of tumour cells in lymph nodes from FFPE tissue
The Journal of Pathology, EarlyView.Abstract
Accurate detection of lymph node (LN) metastases is critical for prognosis and surgical decision‐making in head and neck squamous cell carcinoma (HNSCC) and other epithelial cancers. Standard histopathology examines only a small fraction of LN tissue, limiting sensitivity for micrometastases and isolated tumour cells.Tristan Bergmann, Marianne Hölbling, Monica Sudarsanam, Christiane Driemel, Maximilian E Daniels, Joanna Swierz, Sandra Jaschinski, Maximilian Seidl, Norbert R Kübler, Wolfram T Knoefel, Rui PL Neves, Karl C Sproll, Nikolas H Stoecklein +12 morewiley +1 more sourceLiquid Biopsy: Current Status and Future Perspective in Gastric Cancer and Helicobacter Infection
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2018 Precision medicine stands for 4Ps – precise, preventive, participatory, and personal; in which “precision” is important because the current modern medicine starts from “trial and error,” and “one does not fit all”.Eun A Kang, Young Min Han, Jong Min Park, In Kyung Yoo, Sung Pyo Hong, Ki Baik Hahm +5 moredoaj +1 more sourceCirculating Tumor Cell Synaptophysin and Androgen Receptor Expression Reflect Prostate Cancer Phenotypes in Metastatic Disease
The Prostate, EarlyView.ABSTRACT Background
Chronic exposure to androgen receptor (AR)‐targeted therapies can drive lineage plasticity, leading to treatment resistance and neuroendocrine prostate cancer (NEPC), characterized by loss of AR expression and acquisition of neuroendocrine (NE) markers including synaptophysin (SYP). We evaluated concordance between circulating tumor Ethan Lo, Alisa Clein, Michael Tam, Sara Trimble, Michael Hardin, Arturo Ramirez, Eric Kaldjian, Evan Y. Yu, Heather H. Cheng, Todd A. Yezefski, Andrew C. Hsieh, Petros Grivas, Bruce Montgomery, Peter S. Nelson, Michael T. Schweizer, Daniel E. Sabath, Steven Blinka +16 morewiley +1 more sourceThe nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain +6 morewiley +1 more sourceCirculating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis.
, 2018 We conducted a meta-analysis in nonmetastatic breast cancer patients treated by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (CTC) detection as a prognostic marker.SCOPUS: ar.jinfo:eu-repo/semantics ...Viens, Patrice, Ignatiadis, Michail, Jessica B. Bauldry, Françoise Rothé, Sibylle Loibl, Smerage, Jeffrey, Lucci, Anthony, Jaco Kraan, Maestro, Marisa, Jessica B Bauldry, Meddis, Alessandra, Karhade, Mandar MG, Michiels, Stefan, Daisuke Takata, Borgen, Elin, Laura Muinelo-Romay, Mandar G. Karhade, Fabien Reyal, Pantel, Klaus, Karsten Weber, Rafael Gisbert-Criado, Nagaoka, Rin, Naume, Bjørn, Muinelo-Romay, Laura, Daniele Generali, Bjørn Naume, Michail Ignatiadis, François-Clément Bidard, Antonio Llombart-Cussac, Mandar G Karhade, Takata, Daisuke, Koenraad d'Hollander, Kraan, Jaco, Wolf, Denise M, Laura J. Esserman, Dominic Amara, Pierga, Jean-Yves, Proudhon, Charlotte, Randi R Mathiesen, Mathiesen, Randi R, Mathiesen, Randi RR, Latouche, Aurelien, John W. Park, Hideaki Tokiniwa, Bauldry, Jessica JB, Vicente Carañana, Stefan Michiels, Tokiniwa, Hideaki, Paul Cottu, Carolyn S Hall, Diaz-Rubio, Eduardo, José Vidal-Martínez, Noriyoshi Fujisawa, Jean-Yves Pierga, Jun Horiguchi, Justin Stebbing, Alessandra Meddis, d'Hollander, Koenraad, Naume, Bjorn, Horiguchi, Jun, Cappelletti, M L, Taran, Florin-Andrei, Anthony Lucci, Stebbing, Justin, John W Park, Jose A Garcia-Saenz, Denise M. Wolf, Reyal, Fabien, Cappelletti, Maria Rosa, Paul Blanche, Fujisawa, Noriyoshi, Marisa Maestro, Toi, Masakazu, Onstenk, Wendy, Engebraaten, Olav, Weber, Karsten, Eduardo Diaz-Rubio, Volkmar Mueller, Garcia-Saenz, Jose A, Jose A. Garcia-Saenz, Florin-Andrei Taran, Laura J Esserman, Generali, Daniele, Gisbert-Criado, Rafael, Charlotte Proudhon, Magbanua, Mark Jesus M, Denise M Wolf, Sleijfer, Stefan, Park, John W, Sabine Riethdorf, Wendy Onstenk, Carañana, Vicente, Masakazu Toi, Sara Yvonne Brucker, Riethdorf, Sabine, Vidal-Martínez, José, Brucker, Sara Yvonne, Borgen, E, Rothé, Françoise, Hartkopf, Andreas, Llombart-Cussac, Antonio, Rin Nagaoka, Olav Engebraaten, Maria Rosa Cappelletti, Karhade, Mandar G, Magbanua, Mark Jesus MJM, Bidard, François-Clément, Elin Borgen, Mueller, Volkmar, Randi R. Mathiesen, Esserman, Laura J, Klaus Pantel, Jeffrey Smerage, Stefan Sleijfer, Mark Jesus M. Magbanua, Mark Jesus M Magbanua, Tarantino, Franca, Hall, Carolyn S, Bauldry, Jessica B, Amara, Dominic, Patrice Viens, Blanche, Paul, Cottu, Paul, Loibl, Sibylle, Aurélien Latouche, Carolyn S. Hall, Andreas Hartkopf, Caranana, V, Rothe, F, Magbanua, MJM, Takata, D, Riethdorf, S, Lucci, A, Wolf, DM, Muinelo-Romay, L, Kraan, Jaco; id_orcid, Karhade, MG, Mathiesen, RR, Pantel, K, Michiels, S, Diaz-Rubio, E, Taran, FA, Stebbing, J, Meddis, A, Naume, B, Maestro, M, Hall, CS, Amara, D, Viens, P, Ignatiadis, M, Blanche, P, Reyal, F, Vidal-Martinez, J, Llombart-Cussac, A, Brucker, SY, d'Hollander, K, Weber, K, Engebraaten, O, Hartkopf, A, Bauldry, JB, Esserman, LJ, Horiguchi, J, Tokiniwa, H, Mueller, V, Gisbert-Criado, R, Toi, M, Bidard, FC, Generali, D, Fujisawa, N, Garcia-Saenz, JA, Cappelletti, MR, Smerage, J, Proudhon, C, Nagaoka, R +173 morecore +1 more sourceLiquid Biopsy and Multi‐Cancer Early Detection Tests for Cancer Screening: A Scoping Review
Clinical Genetics, EarlyView.There is a large body of evidence on liquid biopsy and multi‐cancer detection tests for cancer screening. Most studies addressed test performance outcomes, while fewer addressed clinical outcomes, implementation, and cost‐effectiveness. No studies evaluated cancer mortality.Tessa Robinson, Marian Saab, Lily Thao Nguyen, Pooja Kochar, Olivia Meggetto, Jill Tinmouth, Meghan J. Walker +6 morewiley +1 more sourceCurrent status of liquid biopsies for the detection and management of prostate cancer
Cancer Management and Research, 2019 Yi-Tsung Lu, Kevin Delijani, Andrew Mecum, Amir GoldkornDivision of Medical Oncology, Department of Medicine, Keck School of Medicine and Translational and Clinical Science Program, USC Norris Comprehensive Cancer Center, University of Southern ...Lu YT, Delijani K, Mecum A, Goldkorn Adoaj